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Shuanghu Yuan
Mayo Clinic College of Medicine
University of Science and Technology of China
Anhui
Language: Chinese, English
Radiation Therapy
Proton Therapy
Precision Radiotherapy
Radiation Immunotherapy
Molecular Imaging
Ai In Oncology
Genomics
Proteomics
Tumor Diagnosis
Treatment Prediction
Areas of Focus
- Radiation Oncology
- Oncology
- Medical Imaging and Nuclear Medicine
Work Experience
- 1995-10 to 2000-08 - Hebei Hengshui Friendship Hospital - Oncology Department
- 1996-09 to 1997-09 - Peking University Cancer Hospital - Oncology Internal Medicine (Advanced Study)
- 2002-08 to 2003-02 - Tianjin Medical University Cancer Hospital - Breast Surgery (Advanced Study)
- 2003-07 to 2023-12 - Shandong Cancer Hospital - Radiotherapy Department
- 2024-01 to Present - University of Science and Technology of China - Professor
- 2024-02 to Present - First Affiliated Hospital of USTC - Vice President and Dean
Academic Background & Achievements
- 1992-09 to 1995-07 Clinical Medicine: Zhangjiakou Medical College
- 2000-09 to 2003-06 Physiology, Master's: Jiangxi Medical College
- 2004-09 to 2007-06 Oncology, PhD: Tianjin Medical University
- 2008-11 to 2010-12 Postdoctoral in Radiation Oncology: University of Michigan
Publications
- Recurrence/prognosis estimation using a molecularly positive surgical margin-based model calls for alternative curative strategies in pIIIA/N2 NSCLC., Li L, He K, Zhou T, Xu Y, Pang J, Yu Q, Gao Y, Shi H, Zhu H, Li M, Yu J*, Yuan S*., 2024
- Multi-omics predictive model based on clinical, radiomic and genomic features for predicting the response of limited-stage small cell lung cancer to definitive chemoradiotherapy., Li L, Duan J, Gao Y, Yin Y, Yang F, Tang W, Song X, Hu T, Cui J, Yu J, Yuan S*., 2024
- Value of [18F]AlF-NOTA-FAPI-04 PET/CT for differential diagnosis of malignant and various inflammatory lung lesions: comparison with [18F]FDG PET/CT., Qiao K, Qin X, Fu S, Ren J, Jia J, Hu X, Tao Y, Yuan S*, Wei Y*., 2024
- Compound Kushen Injection Reduces Severe Toxicity and Symptom Burden Associated With Curative Radiotherapy in Patients With Lung Cancer., Liu J, Yu Q, Wang XS, Shi Q, Wang J, Wang F, Ren S, Jin J, Han B, Zhang W, Su X, Yuan S*, Lin H*., 2023
- Early and Accurate Detection of Radiation-induced Heart Damage by Cardiodynamicsgram., Tao Y, Sun Q, Wei Y, Liang C, Tang S, Li J, Pei J, Li Y, Wang C*, Yuan S*., 2023
- Genomic features, evolutionary patterns and minimal residual disease at surgical margins as novel prognostic/predictive biomarkers in locally advanced rectal cancer., He K, Li L, Li A, Xu Y, Pang J, Mu D, Ma J, Ge H, Maleki A, Qin X, Zhang X, Ou Q, Shao Y, Yu J, Yuan S*., 2023
- Model integrating CT-based radiomics and genomics for survival prediction in esophageal cancer patients receiving definitive chemoradiotherapy., Cui J, Li L, Liu N, Hou W, Dong Y, Yang F, Zhu S, Li J*, Yuan S*., 2023
- Correlation of Mean Heart Dose and Cardiac Biomarkers with Electrocardiographic Changes in Patients Receiving Thoracic Radiation Therapy., Tao Y, Lu J, Deng W, Ma R, Tang S, Wei Y*, Yuan S*., 2023
- Response Prediction Using 18F-FAPI-04 PET/CT in Patients with Esophageal Squamous Cell Carcinoma Treated with Concurrent Chemoradiotherapy., Hu X, Zhou T, Ren J, Duan J, Wu H, Liu X, Mu Z, Liu N, Wei Y*, Yuan S*., 2023
- Early diagnosis of brain metastases using cerebrospinal fluid cell-free DNA-based breakpoint motif and mutational features in lung cancer., Qin X, Bai Y, Zhou S, Shi H, Liu X, Wang S, Wu X, Pang J, Song X, Fan X, Ou Q, Xu Y, Bao H, Li L, Li J, Shao Y, Yuan S*., 2023
- Clinical Outcome-Related Cancer Pathways and Mutational Signatures in Patients With Unresectable Esophageal Squamous Cell Carcinoma Treated With Chemoradiotherapy., Li L, Sun J, Liu N, Yu R, Zhang J, Pang J, Ou Q, Yin Y, Cui J, Yao X, Zhao R, Shao Y*, Yuan S*, Yu J*., 2023
- [18F]AlF-NOTA-FAPI-04: FAP-targeting specificity, biodistribution, and PET/CT imaging of various cancers., Wei Y, Zheng J, Ma L, Liu X, Xu S, Wang S, Pei J, Cheng K*, Yuan S*, Yu J*., 2022
- [18F]AlF-NOTA-FAPI-04 PET/CT uptake in metastatic lesions on PET/CT imaging might distinguish different pathological types of lung cancer., Wei Y, Cheng K, Fu Z, Zheng J, Mu Z, Zhao C, Liu X, Wang S, Yu J*, Yuan S*., 2022
- Pre-treatment 18F-RGD Uptake may Predict Adverse Events during Apatinib Antiangiogenic Therapy., Li L, Zheng J, Liu Z, Huang Y, Xiao J, Wang S, Yu Q, Zhang Q, Hu X, Zhao W, Hou W, Spring Kong FM, Yu J, Yuan S*., 2022
- Upfront brain radiotherapy improves intracranial progression-free survival but not overall survival in lung adenocarcinoma patients with brain metastases: a retrospective, single-institutional analysis from China., Jiang A, Ni M, Li L, Zhao F, Yao Y, Ding X, Yu Q, Zhang L, Yuan S*., 2022
- Genomic Correlates of Unfavorable Outcome in Locally Advanced Cervical Cancer Treated with Neoadjuvant Chemoradiation., Wei Y, Wei C, Chen L, Liu N, Ou Q, Yin JC, Pang J, Fang Z, Wu X, Wang X, Mu D, Shao Y, Yu J*, Yuan S*., 2022
- Comprehensive Next-Generation Sequencing Reveals Novel Predictive Biomarkers of Recurrence and Thoracic Toxicity Risks After Chemoradiation Therapy in Limited Stage Small Cell Lung Cancer., Li L, Tang S, Yin JC, Dong L, Yang Z, Liu Y, Ma J, Chang P, Pang J, Bao H, Mu D, Zheng X, Aishajiang R, He K, Zhang S, Ni M, Wu X, Wang X, Shao Y*, Wang J*, Ge H*, Yu J*, Yuan S*., 2022
- CT-based radiomics signatures can predict the tumor response of non-small cell lung cancer patients treated with first-line chemotherapy and targeted therapy., Yang F, Zhang J, Zhou L, Xia W, Zhang R, Wei H, Feng J, Zhao X, Jian J, Gao X*, Yuan S*., 2021
- F-18-RGD PET/CT imaging reveals characteristics of angiogenesis in non-small cell lung cancer., Li L, Zhao W, Sun X, Liu N, Zhou Y, Luan X, Gao S, Zhao S, Yu J, Yuan S*., 2020
- Developing more sensitive genomic approaches to detect radioresponse in precision radiation oncology: From tissue DNA analysis to circulating tumor DNA., He K, Zhang S, Shao L, Yin J, Wu X, Shao Y, Yuan S*, Yu J*., 2020
- Association of twice-daily radiotherapy with subsequent brain metastases in adults with small cell lung cancer., Zeng H, Li R, Hu C, Qiu G, Ge H, Yu H, Zhang K, Hu M, Zeng P, Xiao D, Miao C, Wei C, Ni M, Shen J, Li H, Yue J, Lu H, Fan B, Zhu H, Hu X, Kong FS, Yu J*, Yuan S*., 2019
- Dosimetric evaluation of four whole brain radiation therapy approaches with hippocampus and inner ear avoidance and simultaneous integrated boost for limited brain metastases., Jiang A, Sun W, Zhao F, Wu Z, Shang D, Yu Q, Wang S, Zhu J, Yang F, Yuan S*., 2019
- Pretreatment PET/CT imaging of angiogenesis based on 18F-RGD tracer uptake may predict antiangiogenic response., Li L, Ma L, Shang D, Liu Z, Yu Q, Wang S, Teng X, Zhang Q, Hu X, Zhao W, Hou W, Jin J, Kong FS, Yu J, Yuan S*., 2019
Awards
- Chinese Medical Science Award (2022): Third Prize
- National Science and Technology Progress Award (2009): Second Prize
- Shandong Science and Technology Progress Award (2016): Second Prize
- National Science and Technology Progress Award (2017): Second Prize
- Chinese Medical Science Award (2017): Third Prize
- Shandong Science and Technology Progress Award (2012): Second Prize
- High Impact Respiratory Academic Paper Award (2016): High Impact Respiratory Academic Paper Award
- International Abstract Award (2015): Corresponding Author
- Best of ASTRO (2020): Best Paper Award
- Best of ASTRO (2020): Best Paper Award
- Best Abstract Award (2018): Corresponding Author
- Sichuan Science and Technology Progress Award (2019): Second Prize
- Jiangxi Medical Science Award (2023): First Prize
