Professor | Qing Lu | Asia Growth Partners

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Name	Qing Lu
Contact Information	luqingtc@connect.ust.hk
Language ability	Chinese, English
Province	Hong Kong

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Name

Qing Lu

Contact Information

luqingtc@connect.ust.hk

Language ability

Chinese, English

Province

Hong Kong

University/Lab Affiliation and Title	Shanghai Jiao Tong University
Faculty	Bio-X Research Institute
Academic Background & Achievements	2005-2009 Bachelor: Nanjing University 2009-2014 Doctorate: Hong Kong University of Science and Technology 2015 Hong Kong Young Scientist Award
Work Experience	2014-2015 - Hong Kong University of Science and Technology - Postdoctoral Researcher 2015-2016 - Hong Kong University of Science and Technology - Research Assistant Professor
Awards	2015: Hong Kong Young Scientist Award

University/Lab Affiliation and Title

Shanghai Jiao Tong University

Faculty

Bio-X Research Institute

Academic Background & Achievements

2005-2009 Bachelor: Nanjing University
2009-2014 Doctorate: Hong Kong University of Science and Technology
2015 Hong Kong Young Scientist Award

Work Experience

2014-2015 - Hong Kong University of Science and Technology - Postdoctoral Researcher
2015-2016 - Hong Kong University of Science and Technology - Research Assistant Professor

Awards

2015: Hong Kong Young Scientist Award

Areas of Focus	Integration of modern structural biology, biochemistry, and cell biology techniques Detailed mechanisms of various myosins in neural network formation and development Pathogenic genes related to brain developmental disorders Structural and biochemical basis for the pathogenesis of various human genetic diseases
Publications	Temporal and spatial assembly of inner ear hair cell ankle link condensate through phase separation., Wang H, Du H, Ren R, Du T, Lin L, Feng Z, Zhao D, Wei X, Zhai X, Wang H, Dong T, Sun JP, Wu H, Xu Z, Lu Q., 2023 A novel heterozygous missense variant of the ARID4A gene identified in Han Chinese families with schizophrenia-diagnosed siblings that interferes with DNA-binding activity., Ren D, Wei X, Lin L, Yuan F, Bi Y, Guo Z, Liu L, Ji L, Yang X, Han K, Yang F, Wu X, Li X, Yi Z, Xu Y, Cai C, Wang P, Li W, He L, Zhou D, Yu T, Shi Y, Lu Q, He G., 2022 Deafness-related protein PDZD7 forms complex with the C-terminal tail of FCHSD2., Huang Wang, Dange Zhao, Haibo Du, Xiaoyan Zhai, Shaoxuan Wu, Lin Lin, Zhigang Xu, Qing Lu., 2022 FCHSD2 cooperates with CDC42 and N-WASP to regulate cell protrusion formation., Xiaoyan Zhai, Yuxin Shen, Xiujuan Zhang, Tianhao Li, Qing Lu, Zhigang Xu., 2022 Structure and Membrane Targeting of the PDZD7 Harmonin Homology Domain (HHD) Associated With Hearing Loss., Lin L, Wang H, Ren D, Xia Y, He G, Lu Q., 2021 Phase separation-mediated condensation of Whirlin-Myo15-Eps8 stereocilia tip complex., Lin L, Shi Y, Wang M, Wang C, Lu Q, Zhu J, Zhang R., 2021 Generation and characterization of an iPSC line (SHCMDLi001-A) from a 12-year-old Chinese Han patient with TRAF7 syndrome and of an iPSC line (SHCMDLi002-A) from a control individual., Song X, Feng J, Lan X, Tang X, Xu W, Shen J, Yu G, Jia J, Zhang H, Lu Q, Wu S., 2021 Mechanistic Basis of Organization of the Harmonin/USH1C-Mediated Brush Border Microvilli Tip-Link Complex., Jianchao Li, Yunyun He, Qing Lu, Mingjie Zhang., 2016 Structure of myosin-1c tail bound to calmodulin provides insights into calcium-mediated conformational coupling., Lu Q, Li J, Ye F, Zhang M., 2015 Cargo recognition and cargo-mediated regulation of unconventional myosins., Lu Q, Li J, Zhang M*., 2014

Areas of Focus

Integration of modern structural biology, biochemistry, and cell biology techniques
Detailed mechanisms of various myosins in neural network formation and development
Pathogenic genes related to brain developmental disorders
Structural and biochemical basis for the pathogenesis of various human genetic diseases

Publications

Temporal and spatial assembly of inner ear hair cell ankle link condensate through phase separation., Wang H, Du H, Ren R, Du T, Lin L, Feng Z, Zhao D, Wei X, Zhai X, Wang H, Dong T, Sun JP, Wu H, Xu Z, Lu Q., 2023
A novel heterozygous missense variant of the ARID4A gene identified in Han Chinese families with schizophrenia-diagnosed siblings that interferes with DNA-binding activity., Ren D, Wei X, Lin L, Yuan F, Bi Y, Guo Z, Liu L, Ji L, Yang X, Han K, Yang F, Wu X, Li X, Yi Z, Xu Y, Cai C, Wang P, Li W, He L, Zhou D, Yu T, Shi Y, Lu Q*, He G*., 2022
Deafness-related protein PDZD7 forms complex with the C-terminal tail of FCHSD2., Huang Wang, Dange Zhao, Haibo Du, Xiaoyan Zhai, Shaoxuan Wu, Lin Lin, Zhigang Xu, Qing Lu., 2022
FCHSD2 cooperates with CDC42 and N-WASP to regulate cell protrusion formation., Xiaoyan Zhai, Yuxin Shen, Xiujuan Zhang, Tianhao Li, Qing Lu, Zhigang Xu., 2022
Structure and Membrane Targeting of the PDZD7 Harmonin Homology Domain (HHD) Associated With Hearing Loss., Lin L, Wang H, Ren D, Xia Y, He G*, Lu Q*., 2021
Phase separation-mediated condensation of Whirlin-Myo15-Eps8 stereocilia tip complex., Lin L, Shi Y, Wang M, Wang C, Lu Q, Zhu J*, Zhang R*., 2021
Generation and characterization of an iPSC line (SHCMDLi001-A) from a 12-year-old Chinese Han patient with TRAF7 syndrome and of an iPSC line (SHCMDLi002-A) from a control individual., Song X, Feng J, Lan X, Tang X, Xu W, Shen J, Yu G, Jia J, Zhang H, Lu Q*, Wu S*., 2021
Mechanistic Basis of Organization of the Harmonin/USH1C-Mediated Brush Border Microvilli Tip-Link Complex., Jianchao Li, Yunyun He, Qing Lu, Mingjie Zhang., 2016
Structure of myosin-1c tail bound to calmodulin provides insights into calcium-mediated conformational coupling., Lu Q, Li J, Ye F, Zhang M., 2015
Cargo recognition and cargo-mediated regulation of unconventional myosins., Lu Q, Li J, Zhang M*., 2014

Structural Biology Biochemistry Cell Biology Myosins Neural Networks Brain Development Pathogenic Genes Genetic Diseases Structural Basis Biochemical Basis

Xuechun Xia - Shanghai Jiao Tong University

Chunling Wan - Shanghai Jiao Tong University

Lin Lin - Shanghai Jiao Tong University

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