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Qing Lu
Bio-X Research Institute
Shanghai Jiao Tong University
Hong Kong
Language: Chinese, English
Structural Biology
Biochemistry
Cell Biology
Myosins
Neural Networks
Brain Development
Pathogenic Genes
Genetic Diseases
Structural Basis
Biochemical Basis
Areas of Focus
- Integration of modern structural biology, biochemistry, and cell biology techniques
- Detailed mechanisms of various myosins in neural network formation and development
- Pathogenic genes related to brain developmental disorders
- Structural and biochemical basis for the pathogenesis of various human genetic diseases
Work Experience
- 2014-2015 - Hong Kong University of Science and Technology - Postdoctoral Researcher
- 2015-2016 - Hong Kong University of Science and Technology - Research Assistant Professor
Academic Background & Achievements
- 2005-2009 Bachelor: Nanjing University
- 2009-2014 Doctorate: Hong Kong University of Science and Technology
- 2015 Hong Kong Young Scientist Award
Publications
- Temporal and spatial assembly of inner ear hair cell ankle link condensate through phase separation., Wang H, Du H, Ren R, Du T, Lin L, Feng Z, Zhao D, Wei X, Zhai X, Wang H, Dong T, Sun JP, Wu H, Xu Z, Lu Q., 2023
- A novel heterozygous missense variant of the ARID4A gene identified in Han Chinese families with schizophrenia-diagnosed siblings that interferes with DNA-binding activity., Ren D, Wei X, Lin L, Yuan F, Bi Y, Guo Z, Liu L, Ji L, Yang X, Han K, Yang F, Wu X, Li X, Yi Z, Xu Y, Cai C, Wang P, Li W, He L, Zhou D, Yu T, Shi Y, Lu Q*, He G*., 2022
- Deafness-related protein PDZD7 forms complex with the C-terminal tail of FCHSD2., Huang Wang, Dange Zhao, Haibo Du, Xiaoyan Zhai, Shaoxuan Wu, Lin Lin, Zhigang Xu, Qing Lu., 2022
- FCHSD2 cooperates with CDC42 and N-WASP to regulate cell protrusion formation., Xiaoyan Zhai, Yuxin Shen, Xiujuan Zhang, Tianhao Li, Qing Lu, Zhigang Xu., 2022
- Structure and Membrane Targeting of the PDZD7 Harmonin Homology Domain (HHD) Associated With Hearing Loss., Lin L, Wang H, Ren D, Xia Y, He G*, Lu Q*., 2021
- Phase separation-mediated condensation of Whirlin-Myo15-Eps8 stereocilia tip complex., Lin L, Shi Y, Wang M, Wang C, Lu Q, Zhu J*, Zhang R*., 2021
- Generation and characterization of an iPSC line (SHCMDLi001-A) from a 12-year-old Chinese Han patient with TRAF7 syndrome and of an iPSC line (SHCMDLi002-A) from a control individual., Song X, Feng J, Lan X, Tang X, Xu W, Shen J, Yu G, Jia J, Zhang H, Lu Q*, Wu S*., 2021
- Mechanistic Basis of Organization of the Harmonin/USH1C-Mediated Brush Border Microvilli Tip-Link Complex., Jianchao Li, Yunyun He, Qing Lu, Mingjie Zhang., 2016
- Structure of myosin-1c tail bound to calmodulin provides insights into calcium-mediated conformational coupling., Lu Q, Li J, Ye F, Zhang M., 2015
- Cargo recognition and cargo-mediated regulation of unconventional myosins., Lu Q, Li J, Zhang M*., 2014
Awards
- 2015: Hong Kong Young Scientist Award
