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Lin Lin
Bio-X Research Institute
Shanghai Jiao Tong University
Shanghai
Language: Chinese, English
Neurodevelopment
Signal Transduction
Biochemistry
Structural Biology
Protein Complexes
Neurological Diseases
Assembly
Regulation
Mechanisms
Research
Areas of Focus
- Biochemical and structural basis of neurodevelopment and signal transduction
- Assembly and regulation mechanisms of important protein complexes related to neurological diseases
Work Experience
- 2015-2019 - Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences - Assistant Researcher
- 2019-present - Bio-X Institute - Researcher
Academic Background & Achievements
- 2004-2008 Bachelor: Nankai University
- 2008-2011 Master: Nankai University
- 2011-2015 PhD: University of Chinese Academy of Sciences, Institute of Biophysics
- 2019 National Natural Science Foundation of China Youth Science Fund Project Leader
Publications
- BubR1 phosphorylates CENP-E as a switch enabling the transition from lateral association to end-on capture of spindle microtubules., Y. Huang, L. Lin, X. Liu, S. Ye, P. Y. Yao, W. Wang, F. Yang, X. Gao, J. Li, Y. Zhang, J. Zhang, Z. Yang, X. Liu, J. Zang, M. Teng, Z. Wang, K. Ruan, X. Ding, L. Li, D. W. Cleveland, R. Zhang, and X. Yao, 2019
- Rab35/ACAP2 and Rab35/RUSC2 Complex Structures Reveal Molecular Basis for Effector Recognition by Rab35 GTPase., L. Lin, Y. Shi, M. Wang, J. Zhu, and R. Zhang, 2019
- Structure of BAI1/ELMO2 complex reveals an action mechanism of adhesion GPCRs via ELMO family scaffolds., Z. Weng, C. Situ, L. Lin, Z. Wu, J. Zhu, and R. Zhang, 2019
- Structural Basis of Highly Specific Interaction between Nephrin and MAGI1 in Slit Diaphragm Assembly and Signaling., Z. Weng, Y. Shang, Z. Ji, F. Ye, L. Lin, R. Zhang and J. Zhu, 2018
- Structural study on two tandem helix bundles of the ROD domain of talin, an integrin activator., L. Lin, X. Song, S. Ye, and R. Zhang, 2015
