Professor | 林霖 | 数字化转型顾问

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Name

林霖

Contact Information

linlin_8626@sjtu.edu.cn

Language ability

中文, 英文

Province

上海

University/Lab Affiliation and Title	上海交通大学
Faculty	Bio-X Research Institute
Academic Background & Achievements	2004-2008 学士: 南开大学 2008-2011 硕士: 南开大学 2011-2015 博士: 中国科学院大学中科院生物物理研究所 2019 国家自然科学基金青年科学基金项目主持人
Work Experience	2015-2019 - 中科院上海生物化学与细胞生物学研究所 - 助理研究员 2019-至今 - Bio-X研究院 - 研究员

University/Lab Affiliation and Title

上海交通大学

Faculty

Bio-X Research Institute

Academic Background & Achievements

Work Experience

Areas of Focus	神经发育及信号转导的生化与结构基础神经疾病相关重要蛋白复合物的组装和调控机制
Publications	BubR1 phosphorylates CENP-E as a switch enabling the transition from lateral association to end-on capture of spindle microtubules., Y. Huang, L. Lin, X. Liu, S. Ye, P. Y. Yao, W. Wang, F. Yang, X. Gao, J. Li, Y. Zhang, J. Zhang, Z. Yang, X. Liu, J. Zang, M. Teng, Z. Wang, K. Ruan, X. Ding, L. Li, D. W. Cleveland, R. Zhang, and X. Yao, 2019 Rab35/ACAP2 and Rab35/RUSC2 Complex Structures Reveal Molecular Basis for Effector Recognition by Rab35 GTPase., L. Lin, Y. Shi, M. Wang, J. Zhu, and R. Zhang, 2019 Structure of BAI1/ELMO2 complex reveals an action mechanism of adhesion GPCRs via ELMO family scaffolds., Z. Weng, C. Situ, L. Lin, Z. Wu, J. Zhu, and R. Zhang, 2019 Structural Basis of Highly Specific Interaction between Nephrin and MAGI1 in Slit Diaphragm Assembly and Signaling., Z. Weng, Y. Shang, Z. Ji, F. Ye, L. Lin, R. Zhang and J. Zhu, 2018 Structural study on two tandem helix bundles of the ROD domain of talin, an integrin activator., L. Lin, X. Song, S. Ye, and R. Zhang, 2015

Areas of Focus

神经发育及信号转导的生化与结构基础
神经疾病相关重要蛋白复合物的组装和调控机制

Publications

BubR1 phosphorylates CENP-E as a switch enabling the transition from lateral association to end-on capture of spindle microtubules., Y. Huang, L. Lin, X. Liu, S. Ye, P. Y. Yao, W. Wang, F. Yang, X. Gao, J. Li, Y. Zhang, J. Zhang, Z. Yang, X. Liu, J. Zang, M. Teng, Z. Wang, K. Ruan, X. Ding, L. Li, D. W. Cleveland, R. Zhang, and X. Yao, 2019
Rab35/ACAP2 and Rab35/RUSC2 Complex Structures Reveal Molecular Basis for Effector Recognition by Rab35 GTPase., L. Lin, Y. Shi, M. Wang, J. Zhu, and R. Zhang, 2019
Structure of BAI1/ELMO2 complex reveals an action mechanism of adhesion GPCRs via ELMO family scaffolds., Z. Weng, C. Situ, L. Lin, Z. Wu, J. Zhu, and R. Zhang, 2019
Structural Basis of Highly Specific Interaction between Nephrin and MAGI1 in Slit Diaphragm Assembly and Signaling., Z. Weng, Y. Shang, Z. Ji, F. Ye, L. Lin, R. Zhang and J. Zhu, 2018
Structural study on two tandem helix bundles of the ROD domain of talin, an integrin activator., L. Lin, X. Song, S. Ye, and R. Zhang, 2015

神经发育信号转导生物化学结构生物学蛋白复合物神经疾病组装调控机制研究

张曼菲 - 上海交通大学

Area of Focus
颅面 | 表型 | 量化 | 数据库 | 遗传学 | 进化 | 外貌 | 精神健康 | 调控 | 机制

刘慧娟 - 上海交通大学

Area of Focus
干细胞 | 自我更新 | 分化 | 衰老 | 调控 | 间充质 | Dna损伤 | 肿瘤发生 | 应激反应 | 机制

郭熙志 - 上海交通大学

Area of Focus
骨质疏松 | 骨关节炎 | 机理 | 脂肪代谢 | 糖尿病 | 调控 | 基因治疗 | 代谢疾病 | 研究 | 开发

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