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Jian Zhou
zhoujian@cqmu.edu.cn
Chinese, English
Chongqing
Chongqing Medical University
Basic Medical Sciences
  • 2000-2004 Bachelor in Chemistry Education: Hunan Normal University
  • 2004-2009 Master in Biochemistry and Molecular Biology: Hunan Normal University
  • Published over 30 SCI papers as corresponding or first author
  • 2009-2012 - Chongqing Medical University, Neuroscience Research Center - Assistant Researcher
  • 2012-2020 - Chongqing Medical University, Neuroscience Research Center - Associate Researcher
  • 2020-present - Chongqing Medical University, Neuroscience Research Center - Researcher
  • 6th Asia-Pacific Human Proteome Organization Young Scientist Travel Award
  • Third Prize of Chinese Medical Science and Technology Award
Molecular research related to neuropsychiatric diseases
  • Serum metabolomics study of narcolepsy type 1 based on ultra-performance liquid chromatography-tandem mass spectrometry., Zhan Q, Wang L, Liu N, Yuan Y, Deng L, Ding Y, Wang, Zhou J, Xie L, 2023
  • A strategy can be used to analyze intracellular interaction proteomics of cell-surface receptors., Liu Y, Zhang M, Liu Z, Li S, Liu H, Huang R, Yi F, Zhou J, 2023
  • Effects of Camk2b Overexpression and Underexpression on the Proteome of Rat Hippocampal Neurons., Yang C, Zhang M, Li S, Yi F, Huang H, Xie H, Liu H, Huang R, Zhou J, 2022
  • Proteomic Insights Into Susceptibility and Resistance to Chronic-Stress-Induced Depression or Anxiety in the Rat Striatum., Cai X, Yang C, Chen J, Gong W, Yi F, Liao W, Huang R, Xie L, Zhou J, 2021
  • Proteomic Response of Rat Pituitary Under Chronic Mild Stress Reveals Insights Into Vulnerability and Resistance to Anxiety or Depression., Tian F, Liu D, Chen J, Liao W, Gong W, Huang R, Xie L, Yi F, Zhou J, 2021
  • Comparative Proteomics of Rat Olfactory Bulb Reveal Insights into Susceptibility and Resiliency to Chronic-stress-induced Depression or Anxiety., Liu D, Cai X, Wang L, Yi F, Liao W, Huang R, Fang C, Chen J, Zhou J, 2021
  • Global effects of RAB3GAP1 dysexpression on the proteome of mouse cortical neurons., Liu Y, Tian F, Li S, Chen W, Gong W, Xie H, Liu D, Huang R, Liao W, Yi F, Zhou J, 2021
  • Intersectional analysis of chronic mild stress-induced lncRNA-mRNA interaction networks in rat hippocampus reveals potential anti-depression/anxiety drug targets., Liao W, Liu Y, Huang H, Xie H, Gong W, Liu D, Tian F, Huang R, Yi F, Zhou J, 2021
  • Analysis of Chronic Mild Stress-Induced Hypothalamic Proteome: Identification of Protein Dysregulations Associated With Vulnerability and Resiliency to Depression or Anxiety., Gong W, Liao W, Fang C, Liu Y, Xie H, Yi F, Huang R, Wang L, Zhou J, 2021
  • Chronic mild stress-induced protein dysregulations correlated with susceptibility and resiliency to depression or anxiety revealed by quantitative proteomics of the rat prefrontal cortex., Liao W, Liu Y, Wang L, Cai X, Xie H, Yi F, Huang R, Fang C, Xie P, Zhou J, 2021
  • Triggering receptor expressed on myeloid cells 2 activation downregulates toll-like receptor 4 expression and ameliorates cognitive impairment in the Abeta(1-42)-induced Alzheimer's disease mouse model., Qin Z, Gu M, Zhou J, Zhang W, Zhao N, Lü Y, Yu W, 2020
  • Hippocampal proteomic changes of susceptibility and resilience to depression or anxiety in a rat model of chronic mild stress., Tang M, Huang H, Li S, Zhou M, Liu Z, Huang R, Liao W, Xie P, Zhou J, 2019
  • Imbalance of Microglial TLR4/TREM2 in LPS-Treated APP/PS1 Transgenic Mice: A Potential Link Between Alzheimer's Disease and Systemic Inflammation., Zhou J, Yu W, Zhang M, Tian X, Li Y, Lü Y, 2019
  • iTRAQ-Based Quantitative Proteomics Suggests Synaptic Mitochondrial Dysfunction in the Hippocampus of Rats Susceptible to Chronic Mild Stress., Xie H, Huang H, Tang M, Wu Y, Huang R, Liu Z, Zhou M, Liao W, Zhou J, 2018
  • Effective lock-in strategy for proteomic analysis of corona complexes bound to amino-free ligands of gold nanoparticles., Zhou M, Tang M, Li S, Peng L, Huang H, Fang Q, Liu Z, Xie P, Li G, Zhou J, 2018
  • Sec23a mediates miR-200c augmented oligometastatic to polymetastatic progression., Sun Z, Zhou S, Tang J, Ye T, Li J, Liu D, Zhou J, Wang J, Rosie Xing H, 2018
  • Quantitative Proteomic Analysis Reveals Synaptic Dysfunction in the Amygdala of Rats Susceptible to Chronic Mild Stress., Zhou M, Liu Z, Yu J, Li S, Tang M, Zeng L, Wang H, Xie H, Peng L, Huang H, Zhou C, Xie P, Zhou J, 2018
  • Proteomic and network analysis of human serum albuminome by integrated use of quick crosslinking and two-step precipitation., Liu Z, Li S, Wang H, Tang M, Zhou M, Yu J, Bai S, Li P, Zhou J, Xie P, 2017
  • In-depth analysis of the synaptic plasma membrane proteome of small hippocampal slices using an integrated approach., Qiao R, Li S, Zhou M, Chen P, Liu Z, Tang M, Zhou J, 2017
  • Quantitative Proteomic Analysis Reveals Molecular Adaptations in the Hippocampal Synaptic Active Zone of Chronic Mild Stress-Unsusceptible Rats., Zhou J, Liu Z, Yu J, Han X, Fan S, Shao W, Chen J, Qiao R, Xie P, 2016
  • Enhanced Detection of Low-Abundance Human Plasma Proteins by Integrating Polyethylene Glycol Fractionation and Immunoaffinity Depletion., Liu Z, Fan S, Liu H, Yu J, Qiao R, Zhou M, Yang Y, Zhou J, Xie P, 2016
  • Identification and validation of argininosuccinate synthase as a candidate urinary biomarker for major depressive disorder., Wu D, Peng Y, Zhou J, Yang YT, Rao CL, Bai SJ, Zhou XY, Chen J, Liao L, Liang ZH, Yang DY, Xie P, 2015
  • iTRAQ-based quantitative analysis of hippocampal postsynaptic density-associated proteins in a rat chronic mild stress model of depression., Han X, Shao W, Liu Z, Fan S, Yu J, Chen J, Qiao R, Zhou J, Xie P, 2015
  • Ipsilateral hippocampal proteomics reveals mitochondrial antioxidative stress impairment in corticallesioned chronic mild stressed rats., Pan J, Liu H, Zhou J, Liu Z, Yang Y, Peng Y, You H, Yang D, Xie P, 2014
  • Acute tryptophan depletion reduces nitric oxide synthase in the rat hippocampus., Liu H, Zhou J, Fang L, Liu Z, Fan S, Xie P, 2013
  • Hippocampal synaptic dysregulation of exo/endocytosis-associated proteins induced in a chronic mild stressed rat model., Hu Y, Zhou J, Fang L, Liu H, Zhan Q, Luo D, Zhou C, Chen J, Li Q, Xie P, 2013
  • Shotgun proteomics and network analysis of ubiquitin-related proteins from human breast carcinoma epithelial cells., Zhou J, Bi D, Lin Y, Chen P, Wang X, Liang S, 2012
  • Preparation and application of a partially degradable gel in mass spectrometry-based proteomic analysis., Zhou J, Hu Y, Lin Y, Liu H, Xie P, 2011
  • Dried polyacrylamide gel absorption: A method for efficient elimination of the interferences from SDS-solubilized protein samples in mass spectrometry-based proteome analysis., Zhou J, Li J, Li J, Chen P, Wang X, Liang S, 2010
  • Gel absorption-based sample preparation for the analysis of membrane proteome by mass spectrometry., Zhou J, Xiong J, Li J, Huang S, Zhang H, He Q, Lin Y, Chen P, Wang X, Liang S, 2010
  • Analysis of integral membrane proteins by heat gel-embedment combined with improved in-gel digestions., Zhou J, Huang S, Bi D, Zhang H, Li J, Lin Y, Chen P, Wang X, Liang S, 2009
  • Development and application of a two-phase, on-membrane digestion method in the analysis of membrane proteome., Zhou J, Lin Y, Deng X, Shen J, He Q, Chen P, Wang X, Liang S, 2008
  • Evaluation of the application of sodium deoxycholate to proteomic analysis of rat hippocampal plasma membrane., Zhou J, Zhou T, Cao R, Liu Z, Shen J, Chen P, Wang X, Liang S, 2006
Neuropsychiatric Molecular Research Diseases Neuroscience Proteomics Depression Anxiety Biomarkers Synaptic

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