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Yunlong Lei
Basic Medical Sciences
Chongqing Medical University
Chongqing
Language: Chinese, English
Tumor
Resistance
Radiotherapy
Chemotherapy
Mechanisms
Oncology
Cancer
Treatment
Biochemistry
Molecular Biology
Areas of Focus
- Research on mechanisms of tumor resistance to radiotherapy and chemotherapy
Work Experience
- 2013-2018 - Chongqing Medical University, School of Basic Medicine, Lecturer
- 2018-2021 - Chongqing Medical University, School of Basic Medicine, Associate Professor
- 2021-present - Chongqing Medical University, School of Basic Medicine, Professor
Academic Background & Achievements
- 2004-2008 Bachelor: Sichuan University, College of Life Sciences, Biotechnology
- 2008-2013 Doctorate: Sichuan University, West China School of Life Sciences, Biochemistry and Molecular Biology
- Achievement: Published over 20 SCI papers as corresponding/first author
Publications
- ROS generation attenuates the anti-cancer effect of CPX on cervical cancer cells by inducing autophagy and inhibiting glycophagy., Fan H, He Y, Xiang J, Zhou J, Wan X, You J, Du K, Li Y, Cui L, Wang Y, Zhang C, Bu Y, Lei Y*., 2022
- B-Myb accelerates colorectal cancer progression through reciprocal feed-forward transactivation of E2F2., Fan X, Wang Y, Jiang T, Liu T, Jin Y, Du K, Niu Y, Zhang C, Liu Z, Lei Y*, Bu Y*., 2021
- CPX Targeting DJ-1 Triggers ROS-induced Cell Death and Protective Autophagy in Colorectal Cancer., Zhou J#, Zhang L#, Wang M#, Zhou L, Feng XP, Yu LL, Lan J, Gao W, Zhang CD, Bu YQ, Huang CH, Zhang HY*, Lei YL*., 2019
- Tubeimoside-I sensitizes colorectal cancer cells to chemotherapy by inducing ROS-mediated impaired autophagolysosomes accumulation., Yan, JH; Dou, XY; Zhou, J; Xiong, YF; Mo, L; Li, LH*; Lei, YL*., 2019
- Identification of ANXA2 (annexin A2) as a specific bleomycin target to induce pulmonary fibrosis by impeding TFEB-mediated autophagic flux., Wang K#, Zhang T#, Lei Y#, Li X#, Jiang J, Lan J, Liu Y, Chen H, Gao W, Xie N, Chen Q, Zhu X, Liu X, Xie K, Peng Y, Nice EC, et al., 2018
- DJ-1 promotes colorectal cancer progression through activating PLAGL2/Wnt/BMP4 axis., Zhou J, Liu H, Zhang L, Liu X, Zhang C, Wang Y, He Q, Zhang Y, Li Y, Chen Q, Zhang L, Wang K, Bu Y and Lei Y., 2018
- Tubeimoside I induces accumulation of impaired autophagolysosome against cervical cancer cells by both initiating autophagy and inhibiting lysosomal function., Feng X, Zhou J, Li J, Hou X, Li L, Chen Y, Fu S, Zhou L, Li C and Lei Y., 2018
- Ciclopirox Olamine Induces Proliferation Inhibition and Protective Autophagy in Hepatocellular Carcinoma., Wan, X., J. Xiang, H. Fan, Y. Jiang, Y. Lu, C. Zhang, Y. Zhang, Q. Chen*, and Y. Lei*., 2023
- Cell-surface translocation of annexin A2 contributes to bleomycin-induced pulmonary fibrosis by mediating inflammatory response in mice., Lei YL#, Wang K#, Li XF#, Li Y, Feng XP, Zhou J, Zhang Z, Huang CH and Zhang T., 2019
Awards
- 2021: First Prize in Natural Science by the Ministry of Education for research on redox signaling in tumor development
