Professor | Zhe Chen | Asia Growth Partners

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Name	Zhe Chen
Contact Information	chenzhe925@cqmu.edu.cn
Language ability	Chinese, English
Province	Chongqing

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Name

Zhe Chen

Contact Information

chenzhe925@cqmu.edu.cn

Language ability

Chinese, English

Province

Chongqing

University/Lab Affiliation and Title	Chongqing Medical University
Faculty	Basic Medical Sciences
Academic Background & Achievements	2009-2013 Bachelor in Bioengineering: Wuhan University of Science and Technology 2013-2016 Master in Biomedical Engineering: Chongqing University 2017-2020 PhD in Biomedical Engineering: Chongqing University Published 10 SCI papers as first or corresponding author Granted two national invention patents Contributed to the textbook 'Biomechanics of Tissue Repair'
Work Experience	2016-2017 - Research Intern - Department of Hematology, First Affiliated Hospital of Army Medical University 2020-2022 - Associate Researcher - Department of Hematology, First Affiliated Hospital of Army Medical University 2022-present - Associate Researcher - Chongqing Medical University

University/Lab Affiliation and Title

Chongqing Medical University

Faculty

Basic Medical Sciences

Academic Background & Achievements

2009-2013 Bachelor in Bioengineering: Wuhan University of Science and Technology
2013-2016 Master in Biomedical Engineering: Chongqing University
2017-2020 PhD in Biomedical Engineering: Chongqing University
Published 10 SCI papers as first or corresponding author
Granted two national invention patents
Contributed to the textbook 'Biomechanics of Tissue Repair'

Work Experience

2016-2017 - Research Intern - Department of Hematology, First Affiliated Hospital of Army Medical University
2020-2022 - Associate Researcher - Department of Hematology, First Affiliated Hospital of Army Medical University
2022-present - Associate Researcher - Chongqing Medical University

Areas of Focus	Epigenetic regulation mechanisms in hematopoietic stem cell homeostasis Molecular mechanisms and targeted interventions in fusion gene-driven leukemia stem cell formation
Publications	Targeting FTO suppresses hepatocellular carcinoma by inhibiting ERBB3 and TUBB4A expression., Lingli Jiang, Lui Liang, Qing Luo, Zhe Chen, Guanbin Song, 2024 Overcoming adaptive resistance in AML by synergistically targeting FOXO3A-GNG7-mTOR axis with FOXO3A inhibitor Gardenoside and rapamycin., Zhe Chen#, Qian Guo#, Shichen Huang, Lei Li, Feng Wu, Zhilong Liu, Zhigang Li, Tao Chen, Guanbin Song, Shuangnian Xu, Jieping Chen, Yu Hou, 2023 Molecular regulation of hematopoietic stem cell quiescence., Zhe Chen#, Qian Guo#, Guanbin Song, Yu Hou, 2022 Nuclear DEK preserves hematopoietic stem cells potential via NcoR1/HDAC3-Akt1/2-mTOR axis., Zhe Chen, Dawei Huo, Lei Li, Zhilong Liu, Zhigang Li, Shuangnian Xu, Yongxiu Huang, Wei Wu, Chengfang Zhou, Yuanyuan Liu, Mei Kuang, Feng Wu, Hui Li, Pengxu Qian, Guanbin Song, Xudong Wu, Jieping Chen, Yu Hou, 2021 Forkhead Box M1 transcriptionally regulates the expression of long noncoding RNA Snhg8 and Gm26917 to promote proliferation and survival of muscle satellite cells., Zhe Chen, Nuping Bu, Xiaohong Qiao, Zhixiang Zuo, Yahai Shu, Zhilong Liu, Zhijian Qian, Jieping Chen, Yu Hou, 2018

Areas of Focus

Epigenetic regulation mechanisms in hematopoietic stem cell homeostasis
Molecular mechanisms and targeted interventions in fusion gene-driven leukemia stem cell formation

Publications

Targeting FTO suppresses hepatocellular carcinoma by inhibiting ERBB3 and TUBB4A expression., Lingli Jiang, Lui Liang, Qing Luo, Zhe Chen*, Guanbin Song*, 2024
Overcoming adaptive resistance in AML by synergistically targeting FOXO3A-GNG7-mTOR axis with FOXO3A inhibitor Gardenoside and rapamycin., Zhe Chen#, Qian Guo#, Shichen Huang, Lei Li, Feng Wu, Zhilong Liu, Zhigang Li, Tao Chen, Guanbin Song, Shuangnian Xu*, Jieping Chen*, Yu Hou*, 2023
Molecular regulation of hematopoietic stem cell quiescence., Zhe Chen#, Qian Guo#, Guanbin Song*, Yu Hou*, 2022
Nuclear DEK preserves hematopoietic stem cells potential via NcoR1/HDAC3-Akt1/2-mTOR axis., Zhe Chen, Dawei Huo, Lei Li, Zhilong Liu, Zhigang Li, Shuangnian Xu, Yongxiu Huang, Wei Wu, Chengfang Zhou, Yuanyuan Liu, Mei Kuang, Feng Wu, Hui Li, Pengxu Qian, Guanbin Song, Xudong Wu*, Jieping Chen*, Yu Hou*, 2021
Forkhead Box M1 transcriptionally regulates the expression of long noncoding RNA Snhg8 and Gm26917 to promote proliferation and survival of muscle satellite cells., Zhe Chen, Nuping Bu, Xiaohong Qiao, Zhixiang Zuo, Yahai Shu, Zhilong Liu, Zhijian Qian, Jieping Chen*, Yu Hou*, 2018

Hematopoietic Stem Cells Epigenetic Regulation Homeostasis Fusion Genes Leukemia Stem Cell Formation Molecular Mechanisms Targeted Interventions Gene Expression Cellular Biology

Chi Liu - Central South University

Wenbo Liu - Guangzhou Medical University

Xiaoming Wang - Nanjing Medical University

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