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Yunlong Lei
Basic Medical Sciences
Chongqing Medical University
Chongqing
Language: Chinese, English
Tumor
Resistance
Radiotherapy
Chemotherapy
Mechanisms
Oncology
Cancer
Biochemistry
Molecular Biology
Research
Areas of Focus
- Research on mechanisms of tumor resistance to radiotherapy and chemotherapy
Work Experience
- 2013-2018 Lecturer at Chongqing Medical University
- 2018-2021 Associate Professor at Chongqing Medical University
- 2021-present Professor at Chongqing Medical University
Academic Background & Achievements
- 2004-2008 Bachelor in Biotechnology: Sichuan University
- 2008-2013 PhD in Biochemistry and Molecular Biology: Sichuan University
- Hosted over 10 national and provincial projects
- Received the first prize of the Ministry of Education's Higher Education Scientific Research Outstanding Achievement Award (Science and Technology)
Publications
- ROS generation attenuates the anti-cancer effect of CPX on cervical cancer cells by inducing autophagy and inhibiting glycophagy., Fan H, He Y, Xiang J, Zhou J, Wan X, You J, Du K, Li Y, Cui L, Wang Y, Zhang C, Bu Y, Lei Y*., 2022
- B-Myb accelerates colorectal cancer progression through reciprocal feed-forward transactivation of E2F2., Fan X, Wang Y, Jiang T, Liu T, Jin Y, Du K, Niu Y, Zhang C, Liu Z, Lei Y*, Bu Y*., 2021
- CPX Targeting DJ-1 Triggers ROS-induced Cell Death and Protective Autophagy in Colorectal Cancer., Zhou J#, Zhang L#, Wang M#, Zhou L, Feng XP, Yu LL, Lan J, Gao W, Zhang CD, Bu YQ, Huang CH, Zhang HY*, Lei YL*., 2019
- Tubeimoside-I sensitizes colorectal cancer cells to chemotherapy by inducing ROS-mediated impaired autophagolysosomes accumulation., Yan, JH; Dou, XY; Zhou, J; Xiong, YF; Mo, L; Li, LH*; Lei, YL*., 2019
- Identification of ANXA2 (annexin A2) as a specific bleomycin target to induce pulmonary fibrosis by impeding TFEB-mediated autophagic flux., Wang K#, Zhang T#, Lei Y#, Li X#, Jiang J, Lan J, Liu Y, Chen H, Gao W, Xie N, Chen Q, Zhu X, Liu X, Xie K, Peng Y, Nice EC, et al., 2018
- DJ-1 promotes colorectal cancer progression through activating PLAGL2/Wnt/BMP4 axis., Zhou J, Liu H, Zhang L, Liu X, Zhang C, Wang Y, He Q, Zhang Y, Li Y, Chen Q, Zhang L, Wang K, Bu Y and Lei Y., 2018
- Tubeimoside I induces accumulation of impaired autophagolysosome against cervical cancer cells by both initiating autophagy and inhibiting lysosomal function., Feng X, Zhou J, Li J, Hou X, Li L, Chen Y, Fu S, Zhou L, Li C and Lei Y., 2018
- Ciclopirox Olamine Induces Proliferation Inhibition and Protective Autophagy in Hepatocellular Carcinoma., Wan, X., J. Xiang, H. Fan, Y. Jiang, Y. Lu, C. Zhang, Y. Zhang, Q. Chen*, and Y. Lei*., 2023
- Cell-surface translocation of annexin A2 contributes to bleomycin-induced pulmonary fibrosis by mediating inflammatory response in mice., Lei YL#, Wang K#, Li XF#, Li Y, Feng XP, Zhou J, Zhang Z, Huang CH and Zhang T., 2019
Awards
- 2021: First Prize in Natural Science by the Ministry of Education for research on redox signaling in tumor development
