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雷云龙
Basic Medical Sciences
重庆医科大学
重庆
Language: 中文, 英语
肿瘤
抵抗
放疗
化疗
机制
肿瘤学
癌症
生物化学
分子生物学
研究
Areas of Focus
- 肿瘤放化疗抵抗机制研究
Work Experience
- 2013-2018 重庆医科大学讲师
- 2018-2021 重庆医科大学副教授
- 2021-至今 重庆医科大学教授
Academic Background & Achievements
- 2004-2008 生物技术学士：四川大学
- 2008-2013 生物化学与分子生物学博士：四川大学
- 主持国家及省级项目10余项
- 获得教育部高等学校科学研究优秀成果奖（科学技术）一等奖
Publications
- ROS generation attenuates the anti-cancer effect of CPX on cervical cancer cells by inducing autophagy and inhibiting glycophagy., Fan H, He Y, Xiang J, Zhou J, Wan X, You J, Du K, Li Y, Cui L, Wang Y, Zhang C, Bu Y, Lei Y*., 2022
- B-Myb accelerates colorectal cancer progression through reciprocal feed-forward transactivation of E2F2., Fan X, Wang Y, Jiang T, Liu T, Jin Y, Du K, Niu Y, Zhang C, Liu Z, Lei Y*, Bu Y*., 2021
- CPX Targeting DJ-1 Triggers ROS-induced Cell Death and Protective Autophagy in Colorectal Cancer., Zhou J#, Zhang L#, Wang M#, Zhou L, Feng XP, Yu LL, Lan J, Gao W, Zhang CD, Bu YQ, Huang CH, Zhang HY*, Lei YL*., 2019
- Tubeimoside-I sensitizes colorectal cancer cells to chemotherapy by inducing ROS-mediated impaired autophagolysosomes accumulation., Yan, JH; Dou, XY; Zhou, J; Xiong, YF; Mo, L; Li, LH*; Lei, YL*., 2019
- Identification of ANXA2 (annexin A2) as a specific bleomycin target to induce pulmonary fibrosis by impeding TFEB-mediated autophagic flux., Wang K#, Zhang T#, Lei Y#, Li X#, Jiang J, Lan J, Liu Y, Chen H, Gao W, Xie N, Chen Q, Zhu X, Liu X, Xie K, Peng Y, Nice EC, et al., 2018
- DJ-1 promotes colorectal cancer progression through activating PLAGL2/Wnt/BMP4 axis., Zhou J, Liu H, Zhang L, Liu X, Zhang C, Wang Y, He Q, Zhang Y, Li Y, Chen Q, Zhang L, Wang K, Bu Y and Lei Y., 2018
- Tubeimoside I induces accumulation of impaired autophagolysosome against cervical cancer cells by both initiating autophagy and inhibiting lysosomal function., Feng X, Zhou J, Li J, Hou X, Li L, Chen Y, Fu S, Zhou L, Li C and Lei Y., 2018
- Ciclopirox Olamine Induces Proliferation Inhibition and Protective Autophagy in Hepatocellular Carcinoma., Wan, X., J. Xiang, H. Fan, Y. Jiang, Y. Lu, C. Zhang, Y. Zhang, Q. Chen*, and Y. Lei*., 2023
- Cell-surface translocation of annexin A2 contributes to bleomycin-induced pulmonary fibrosis by mediating inflammatory response in mice., Lei YL#, Wang K#, Li XF#, Li Y, Feng XP, Zhou J, Zhang Z, Huang CH and Zhang T., 2019
Awards
- 2021年：教育部自然科学一等奖，研究氧化还原信号在肿瘤发生发展中的机制
