Professor | Bo Wen | Asia Growth Partners

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Name	Bo Wen
Contact Information	bowen@cqmu.edu.cn
Language ability	English, Chinese
Province	Chongqing

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Name

Bo Wen

Contact Information

bowen@cqmu.edu.cn

Language ability

English, Chinese

Province

Chongqing

University/Lab Affiliation and Title	Chongqing Medical University
Faculty	Basic Medical Sciences
Academic Background & Achievements	1993-1997 Bachelor: Yunnan University, Biology 1997-2000 Master: Yunnan University, Biology, Supervisor: Chun-Jie Xiao 2000-2004 PhD: Fudan University, Genetics, Supervisor: Li Jin 2005-2009 Postdoctoral: Johns Hopkins University, Medicine, Supervisor: Andrew Feinberg Published over 48 academic papers with more than 7500 citations Published over 20 research papers as first or corresponding author in journals like Nature, Nature Genetics, Molecular Cell, Genome Research
Work Experience	2009-2010 - Johns Hopkins University, Lecturer 2010-2017 - Fudan University, Researcher at Biomedical Research Institute 2017-2023 - Fudan University, Researcher at Basic Medical Sciences 2023.7-present - Chongqing Medical University, Dean of Basic Medical Sciences
Awards	2005: First Prize in Natural Science, Yunnan Province 2006: National Excellent Doctoral Dissertation 2010: Shanghai Shuguang Scholar 2011: Shanghai Pujiang Talent 2011: Outstanding Young Talent in Shanghai Health System 2015: Chief Scientist of National Major Scientific Research Program (973) 2022: Bayu Scholar Lecture 2023: Leading Expert of Chongqing Chief Expert Studio 2023: Changjiang Scholar Distinguished Professor

University/Lab Affiliation and Title

Chongqing Medical University

Faculty

Basic Medical Sciences

Academic Background & Achievements

1993-1997 Bachelor: Yunnan University, Biology
1997-2000 Master: Yunnan University, Biology, Supervisor: Chun-Jie Xiao
2000-2004 PhD: Fudan University, Genetics, Supervisor: Li Jin
2005-2009 Postdoctoral: Johns Hopkins University, Medicine, Supervisor: Andrew Feinberg
Published over 48 academic papers with more than 7500 citations
Published over 20 research papers as first or corresponding author in journals like Nature, Nature Genetics, Molecular Cell, Genome Research

Work Experience

2009-2010 - Johns Hopkins University, Lecturer
2010-2017 - Fudan University, Researcher at Biomedical Research Institute
2017-2023 - Fudan University, Researcher at Basic Medical Sciences
2023.7-present - Chongqing Medical University, Dean of Basic Medical Sciences

Awards

2005: First Prize in Natural Science, Yunnan Province
2006: National Excellent Doctoral Dissertation
2010: Shanghai Shuguang Scholar
2011: Shanghai Pujiang Talent
2011: Outstanding Young Talent in Shanghai Health System
2015: Chief Scientist of National Major Scientific Research Program (973)
2022: Bayu Scholar Lecture
2023: Leading Expert of Chongqing Chief Expert Studio
2023: Changjiang Scholar Distinguished Professor

Areas of Focus	Ultrastructure of Cell Nucleus and Disease Occurrence Human Genetics and Epigenetics
Publications	The Nuclear Matrix Protein SAFB Cooperates with Major Satellite RNAs to Stabilize Heterochromatin Architecture Partially through Phase Separation, Huo X, Ji L, Zhang Y, Lv P, Cao X, Wang Q, Yan Z, Dong S, Du D, Zhang F, Wei G, Liu Y, Wen B, 2020 The nuclear matrix protein HNRNPU maintains 3D genome architecture globally in mouse hepatocytes, Fan H#, Lv P#, Huo X, Wu J, Wang Q, Cheng L, Liu Y, Tang QQ, Zhang L, Zhang F, Zheng X, Wu H, Wen B, 2018 MATR3-antisense LINE1 RNA meshwork scaffolds higher-order chromatin organization, Zhang Y#, Cao X#, Gao Z#, Ma X#, Wang Q, Xu X, Cai X, Zhang Y, Zhang Z, Wei G,Wen B, 2023 The nuclear bodies formed by histone demethylase KDM7A, Ming H#, Wang Q#, Zhang Y, Ji L, Cheng L, Huo X, Yan Z, Dang Y and Wen B, 2021 The Lysine Demethylase KDM7A Regulates Immediate Early Genes in Neurons, Wang Y#, Hong Q, Xia Y#, Zhang Z, Wen B, 2023 The Long Noncoding RNA Lncenc1 Maintains Naive States of Mouse ESCs by Promoting the Glycolysis Pathway, Sun Z#, Zhu M#, Lv P, Cheng L, Wang Q, Tian P, Yan Z, Wen B, 2018 Disruption of nuclear speckles reduces chromatin interactions in active compartments, Hu S#, Lv P#, Yan Z, Wen B, 2019 Large histone H3 lysine-9 dimethylated chromatin blocks distinguish differentiated from embryonic stem cells, Wen B, Wu H, Shinkai Y, Irizarry R and Feinberg AP, 2009 Differential methylation of tissue- and cancer specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts, Doi A#, Park IH#, Wen B#, Murakami P, Aryee M, Irizarry R, Herb B, Ladd-Acosta C, Rho J, Loewer S, Miller J, Schlaeger T, Daley GQ and Feinberg AP, 2009 Analyses of genetic structure of Tibeto-Burman populations reveals sex-biased admixture in southern Tibeto-Burmans, Wen B, Xie X, Gao S, Li H, Shi H, Song X, Qian T, Xiao C, Jin J, Su B, Lu D, Chakraborty R, Jin L*, 2004

Areas of Focus

Ultrastructure of Cell Nucleus and Disease Occurrence
Human Genetics and Epigenetics

Publications

The Nuclear Matrix Protein SAFB Cooperates with Major Satellite RNAs to Stabilize Heterochromatin Architecture Partially through Phase Separation, Huo X, Ji L, Zhang Y, Lv P, Cao X, Wang Q, Yan Z, Dong S, Du D, Zhang F, Wei G, Liu Y, Wen B*, 2020
The nuclear matrix protein HNRNPU maintains 3D genome architecture globally in mouse hepatocytes, Fan H#, Lv P#, Huo X, Wu J, Wang Q, Cheng L, Liu Y, Tang QQ, Zhang L, Zhang F, Zheng X, Wu H, Wen B*, 2018
MATR3-antisense LINE1 RNA meshwork scaffolds higher-order chromatin organization, Zhang Y#, Cao X#, Gao Z#, Ma X#, Wang Q, Xu X, Cai X, Zhang Y, Zhang Z, Wei G*,Wen B*, 2023
The nuclear bodies formed by histone demethylase KDM7A, Ming H#, Wang Q#, Zhang Y, Ji L, Cheng L, Huo X, Yan Z, Dang Y and Wen B*, 2021
The Lysine Demethylase KDM7A Regulates Immediate Early Genes in Neurons, Wang Y#, Hong Q, Xia Y#, Zhang Z*, Wen B*, 2023
The Long Noncoding RNA Lncenc1 Maintains Naive States of Mouse ESCs by Promoting the Glycolysis Pathway, Sun Z#, Zhu M#, Lv P, Cheng L, Wang Q, Tian P, Yan Z, Wen B*, 2018
Disruption of nuclear speckles reduces chromatin interactions in active compartments, Hu S#, Lv P#, Yan Z, Wen B*, 2019
Large histone H3 lysine-9 dimethylated chromatin blocks distinguish differentiated from embryonic stem cells, Wen B, Wu H, Shinkai Y, Irizarry R and Feinberg AP*, 2009
Differential methylation of tissue- and cancer specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts, Doi A#, Park IH#, Wen B#, Murakami P, Aryee M, Irizarry R, Herb B, Ladd-Acosta C, Rho J, Loewer S, Miller J, Schlaeger T, Daley GQ and Feinberg AP*, 2009
Analyses of genetic structure of Tibeto-Burman populations reveals sex-biased admixture in southern Tibeto-Burmans, Wen B*, Xie X, Gao S, Li H, Shi H, Song X, Qian T, Xiao C, Jin J, Su B, Lu D, Chakraborty R, Jin L*, 2004

Cell Nucleus Ultrastructure Disease Chromatin Nuclear Matrix Nuclear Bodies Epigenetics Genetics Molecular Mechanisms Research

Shang Yongfeng - Peking University

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