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Xue-Mei Zhang
Laboratory Medicine
Chongqing Medical University
Chongqing
Language: Chinese, English
Bacterial Virulence
Molecular Mechanisms
Regulation
Immunomodulation
Microbial Proteins
Antimicrobial
Antitumor
Mechanisms
Research
Study
Areas of Focus
- Research on the molecular mechanisms regulating bacterial virulence factors
- Study on the immunomodulatory effects of microbial proteins in antimicrobial and antitumor mechanisms
Work Experience
- 1995.07-2000.09 Assistant Lecturer at Basic Medical College, Chongqing Medical University
- 2000.09-present Lecturer, Associate Professor, Professor at School of Laboratory Medicine, Chongqing Medical University
Academic Background & Achievements
- 1991.09-1995.07 Bachelor in Pharmaceutical Chemistry: West China University of Medical Sciences
- 1997.09-2000.07 Master in Biochemistry and Molecular Biology: West China University of Medical Sciences
- 2000.09-2003.07 Doctorate in Clinical Laboratory Diagnostics: Chongqing Medical University
Publications
- Detoxified pneumolysin derivative ΔA146Ply inhibits autophagy and induces apoptosis in acute myeloid leukemia cells by activating mTOR signaling., Zhu T, Zhang H, Li S, Wu K, Yin Y, Zhang X*, 2022
- IL-6 Prevents Lung Macrophage Death and Lung Inflammation Injury by Inhibiting GSDME- and GSDMD-Mediated Pyroptosis during Pneumococcal Pneumosepsis., Gou X, Xu W, Liu Y, Peng Y, Xu W, Yin Y, Zhang X*, 2022
- Inactivation of Transcriptional Regulator FabT Influences Colony Phase Variation of Streptococcus pneumoniae., Zhang J, Ye W, Wu K, Xiao S, Zheng Y, Shu Z, Yin Y, Zhang X*, 2021
- Progranulin Decreases Susceptibility to Streptococcus pneumoniae in Influenza and Protects against Lethal Coinfection., Wang X, Yuan J, Wang H, Gan N, Zhang Q, Liu B, Wang J, Shu Z, Rao L, Gou X, Zhang H, Yin Y, Zhang X*, 2019
- Engineering detoxified pneumococcal pneumolysin derivativeΔA146PLY for self-biomineralization of calcium phosphate: Assessment of their protective efficacy in murine infection models., Wu J, Wu K, Xu W, Yuan T, Wang X, Zhang J, Min Y, Yin Y, Zhang X*, 2018
