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Yangguang Shao
Life Science
China Medical University
Liaoning
Language: Chinese, English
Epigenetics
Tumorigenesis
Transcriptional Regulation
Histone Modification
Alternative Splicing
Protein Ubiquitination
Cancer
Cell Biology
Molecular Biology
Genetics
Areas of Focus
- Epigenetics and Tumorigenesis Mechanisms
Work Experience
- 2005-present - China Medical University - Professor
Academic Background & Achievements
- 1998 - Bachelor's Degree in Biotechnology: Northeast Normal University
- 2001 - Master's Degree in Cell Biology: Northeast Normal University
- 2005 - Doctorate in Cell Biology: Northeast Normal University
- 2014 - Participated in winning the Second Prize of Liaoning Provincial Science and Technology Progress Award
Publications
- MORC2 regulates RBM39-mediated CDK5RAP2 alternative splicing to promote EMT and metastasis in colon cancer., He Y, Shao Y, Zhou Z, Li T, Gao Y, Liu X, Yuan G, Yang G, Zhang L, Li F, 2024
- Histone demethylase Jumonji domain-containing 1A inhibits proliferation and progression of gastric cancer by upregulating runt-related transcription factor 3., Ning K, Shao Y, He Y, Wang F, Cui X, Liu F, Li D, Li F, 2020
- MORC2 promotes development of an aggressive colorectal cancer phenotype through inhibition of NDRG1., Liu J, Shao Y, He Y, Ning K, Cui X, Liu F, Wang Z, Li F, 2019
- Group II p21-activated kinases as therapeutic targets in gastrointestinal cancer., Shao Y, Ning K, Li F, 2016
- Nucleo-cytoplasmic shuttling of PAK4 modulates β-catenin intracellular translocation and signaling., Li Y, Shao Y, Tong Y, Shen T, Zhang J, Li Y, Gu H, Li F, 2012
- Involvement of histone deacetylation in MORC2-mediated down-regulation of carbonic anhydrase IX., Shao Y, Li Y, Zhang J, Liu D, Liu F, Zhao Y, Shen T, Li F, 2010
- Reversible histone acetylation involved in transcriptional regulation of WT1 gene., Shao Y, Lu J, Cheng C, Cui L, Zhang G, Huang B, 2007
- Histone acetyltransferase p300 promotes the activation of human WT1 promoter and intronic enhancer., Shao Y, Lu J, Zhang G, Liu C, Huang B, 2005
Awards
- 2014: Third Prize in the Young Teacher Lecture Competition by the Chinese Society for Cell Biology
