Professor | Yangguang Shao | Asia Growth Partners

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Name	Yangguang Shao
Contact Information	ygshao@cmu.edu.cn
Language ability	Chinese, English
Province	Liaoning

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Name

Yangguang Shao

Contact Information

ygshao@cmu.edu.cn

Language ability

Chinese, English

Province

Liaoning

University/Lab Affiliation and Title	China Medical University
Faculty	Life Sciences
Academic Background & Achievements	1998 - Bachelor's Degree in Biotechnology: Northeast Normal University 2001 - Master's Degree in Cell Biology: Northeast Normal University 2005 - Doctorate in Cell Biology: Northeast Normal University 2014 - Participated in winning the Second Prize of Liaoning Provincial Science and Technology Progress Award
Work Experience	2005-present - China Medical University - Professor
Awards	2014: Third Prize in the Young Teacher Lecture Competition by the Chinese Society for Cell Biology

University/Lab Affiliation and Title

China Medical University

Faculty

Life Sciences

Academic Background & Achievements

1998 - Bachelor's Degree in Biotechnology: Northeast Normal University
2001 - Master's Degree in Cell Biology: Northeast Normal University
2005 - Doctorate in Cell Biology: Northeast Normal University
2014 - Participated in winning the Second Prize of Liaoning Provincial Science and Technology Progress Award

Work Experience

2005-present - China Medical University - Professor

Awards

2014: Third Prize in the Young Teacher Lecture Competition by the Chinese Society for Cell Biology

Areas of Focus	Epigenetics and Tumorigenesis Mechanisms
Publications	MORC2 regulates RBM39-mediated CDK5RAP2 alternative splicing to promote EMT and metastasis in colon cancer., He Y, Shao Y, Zhou Z, Li T, Gao Y, Liu X, Yuan G, Yang G, Zhang L, Li F, 2024 Histone demethylase Jumonji domain-containing 1A inhibits proliferation and progression of gastric cancer by upregulating runt-related transcription factor 3., Ning K, Shao Y, He Y, Wang F, Cui X, Liu F, Li D, Li F, 2020 MORC2 promotes development of an aggressive colorectal cancer phenotype through inhibition of NDRG1., Liu J, Shao Y, He Y, Ning K, Cui X, Liu F, Wang Z, Li F, 2019 Group II p21-activated kinases as therapeutic targets in gastrointestinal cancer., Shao Y, Ning K, Li F, 2016 Nucleo-cytoplasmic shuttling of PAK4 modulates β-catenin intracellular translocation and signaling., Li Y, Shao Y, Tong Y, Shen T, Zhang J, Li Y, Gu H, Li F, 2012 Involvement of histone deacetylation in MORC2-mediated down-regulation of carbonic anhydrase IX., Shao Y, Li Y, Zhang J, Liu D, Liu F, Zhao Y, Shen T, Li F, 2010 Reversible histone acetylation involved in transcriptional regulation of WT1 gene., Shao Y, Lu J, Cheng C, Cui L, Zhang G, Huang B, 2007 Histone acetyltransferase p300 promotes the activation of human WT1 promoter and intronic enhancer., Shao Y, Lu J, Zhang G, Liu C, Huang B, 2005

Areas of Focus

Epigenetics and Tumorigenesis Mechanisms

Publications

MORC2 regulates RBM39-mediated CDK5RAP2 alternative splicing to promote EMT and metastasis in colon cancer., He Y, Shao Y, Zhou Z, Li T, Gao Y, Liu X, Yuan G, Yang G, Zhang L, Li F, 2024
Histone demethylase Jumonji domain-containing 1A inhibits proliferation and progression of gastric cancer by upregulating runt-related transcription factor 3., Ning K, Shao Y, He Y, Wang F, Cui X, Liu F, Li D, Li F, 2020
MORC2 promotes development of an aggressive colorectal cancer phenotype through inhibition of NDRG1., Liu J, Shao Y, He Y, Ning K, Cui X, Liu F, Wang Z, Li F, 2019
Group II p21-activated kinases as therapeutic targets in gastrointestinal cancer., Shao Y, Ning K, Li F, 2016
Nucleo-cytoplasmic shuttling of PAK4 modulates β-catenin intracellular translocation and signaling., Li Y, Shao Y, Tong Y, Shen T, Zhang J, Li Y, Gu H, Li F, 2012
Involvement of histone deacetylation in MORC2-mediated down-regulation of carbonic anhydrase IX., Shao Y, Li Y, Zhang J, Liu D, Liu F, Zhao Y, Shen T, Li F, 2010
Reversible histone acetylation involved in transcriptional regulation of WT1 gene., Shao Y, Lu J, Cheng C, Cui L, Zhang G, Huang B, 2007
Histone acetyltransferase p300 promotes the activation of human WT1 promoter and intronic enhancer., Shao Y, Lu J, Zhang G, Liu C, Huang B, 2005

Epigenetics Tumorigenesis Transcriptional Regulation Histone Modification Alternative Splicing Protein Ubiquitination Cancer Cell Biology Molecular Biology Genetics

Hua Zhou - Southern University of Science and Technology

Feng Ying - University of Chinese Academy of Sciences

Hui Jingyi - University of Chinese Academy of Sciences

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