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Xu Yan
Bioinformatics Science and Technology
Harbin Medical University
Heilongjiang
Language: Chinese, English
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Cancer Bioinformatics Non-Coding Rna Transcription Factors Co-Regulation Multi-Omics Tumor Drug Resistance Single-Cell Sequencing Mechanisms
Areas of Focus
  • Cancer Bioinformatics
  • Non-coding RNA and Transcription Factors in Cancer
  • Cancer Interaction and Co-regulation Mechanisms
  • Tumor Drug Resistance Molecular Mechanisms
Work Experience
  • Current - Harbin Medical University - Director of the Department of Biomedical Engineering
Publications
  • Upregulation of CXCL1 and LY9 contributes to BRCAness in ovarian cancer and mediates response to PARPi and immune checkpoint blockade, Xu Yan, 2022
  • Strongly preserved modules between cancer tissue and cell line contribute to drug resistance analysis across multiple cancer types, Xu Yan, 2021
  • Identification of Primary and Metastatic Lung Cancer-Related lncRNAs and Potential Targeted Drugs Based on ceRNA Network, Xu Yan, 2021
  • An individualized transcriptional signature to predict the epithelial-mesenchymal transition based on relative expression ordering, Xu Yan, 2020
  • Identification and Characterization of the Copy Number Dosage-Sensitive Genes in Colorectal Cancer, Xu Yan, 2020
  • Systematic identification of dysregulated lncRNAs associated with platinum-based chemotherapy response across 11 cancer types, Xu Yan, 2020
  • Optimization of cell lines as tumour models by integrating multi-omics data, Xu Yan, 2017
  • An integrated approach to reveal miRNAs’ impacts on the functional consequence of copy number alterations in cancer, Xu Yan, 2015
  • CNVD: Text Mining-based Copy Number Variation in Disease Database, Xu Yan, 2012
Awards
  • Heilongjiang Provincial Higher Education Science and Technology Award Second Prize (First)
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