Areas of Focus
- Cancer Genomics
- Somatic Genetic Alterations
- Cancer Evolution
Work Experience
- 2021-09 to Present - Harbin Medical University, School of Bioinformatics Science and Technology - Professor
- 2016-07 to 2021-09 - Harbin Medical University, School of Bioinformatics Science and Technology - Associate Professor
- 2016-05 to 2020-08 - Harbin Medical University Third Affiliated Hospital - Postdoctoral Researcher
- 2014-07 to 2016-09 - Harbin Medical University, School of Bioinformatics Science and Technology - Lecturer
Academic Background & Achievements
- 2008-09 to 2014-06 PhD in Biomedical Engineering: Harbin Medical University
- 2003-09 to 2008-06 Bachelor's in Biotechnology: Harbin Medical University
- Published 32 SCI research papers in international journals
Publications
- Identifying core gene modules in glioblastoma based on multilayer factor-mediated dysfunctional regulatory networks through integrating multi-dimensional genomic data, First Author, 2015
- Dissecting the Functional Mechanisms of Somatic Copy-Number Alterations Based on Dysregulated ceRNA Networks across Cancers, First Author, 2020
- Prioritizing Gene Cascading Paths to Model Colorectal Cancer Through Engineered Organoids, First Author, 2020
- Identifying Key Somatic Copy Number Alterations Driving Dysregulation of Cancer Hallmarks in Lower-Grade Glioma, Corresponding Author, 2021
- Systematic investigation of the prognostic impact of clonal status of somatic mutations across multiple cancer types, Corresponding Author, 2022
- Prognostic impact of a lymphocyte activation-associated gene signature in GBM based on transcriptome analysis, Corresponding Author, 2021
- Revealing the functions of clonal driver gene mutations in patients based on evolutionary dependencies, Co-corresponding Author, 2022
- Identifying dysfunctional miRNA-mRNA regulatory modules by inverse activation, cofunction, and high interconnection of target genes: A case study of glioblastoma, Co-first Author, 2013
- IndividualizedPath: identifying genetic alterations contributing to the dysfunctional pathways in glioblastoma individuals, First Author, 2014
Awards
- Chinese Medical Science and Technology Award Third Prize (2015): Identification of cancer risk miRNA and co-regulatory risk pathways
- Harbin City Natural Science and Technology Academic Achievement Second Prize (2014): Identification of dysfunctional miRNA-mRNA regulatory modules in glioblastoma