Foreign Academician of the German Academy of Sciences
Foreign Academician of the French Academy of Medical Sciences
Foreign Academician of the British Academy of Medical Sciences
Published over 230 SCI papers as corresponding author
President of the Chinese Academy of Medical Sciences
President of Peking Union Medical College
Chairman of the Chinese Society of Biomedical Engineering
Chairman of the Life Sciences Union of the Chinese Association for Science and Technology
Secretary-General of the Asia-Pacific Immunology Association
National Natural Science Second Prize (2003)
First Prize of Chinese Medical Science and Technology Award
First Prize of Military and Shanghai Science and Technology Progress Award
First Prize of Shanghai Natural Science Award
Guanghua Engineering Award of the Chinese Academy of Engineering (2012)
Chen Jiageng Life Science Award of the Chinese Academy of Sciences (2016)
China Youth Science and Technology Award
Research
Innate Immunity and Inflammation Tumor Immunotherapy
The RNA helicase DDX46 inhibits innate immunity by entrapping m6A-demethylated antiviral transcripts in the nucleus., Zheng Q, Hou J, Zhou Y, Li Z, Cao X., 2017
Methyltransferase SETD2-mediated methylation of STAT1 is critical for interferon antiviral activity., Chen K, Liu J, Liu S, Xia M, Zhang X, Han D, Jiang Y, Wang C, Cao X., 2017
Tumor Exosomal RNAs promote lung pre-metastatic niche formation by activating alveolar epithelial TLR3 to recruit neutrophils., Liu Y, Gu Y, Han Y, Zhang Q, Jiang Z, Zhang X, Huang B, Xu X, Zheng J, Cao X., 2016
The lectin Siglec-G inhibits dendritic cell cross-presentation by impairing MHC class I-peptide complex formation., Ding Y, Guo Z, Liu Y, Li X, Zhang Q, Xu X, Gu Y, Zhang Y, Zhao D, Cao X., 2016
Methyltransferase Dnmt3a upregulates HDAC9 to deacetylate the kinase TBK1 for activation of antiviral innate immunity., Li X, Zhang Q, Ding Y, Liu Y, Zhao D, Zhao K, Shen Q, Liu X, Zhu X, Li N, Cheng Z, Fan G, Wang Q, Cao X., 2016
K33-linked polyubiquitination of Zap70 by Nrdp1 controls CD8+ T cell activation., Yang M, Chen T, Li X, Yu Z, Tang S, Wang C, Gu Y, Liu Y, Xu S, Li W, Zhang X, Wang J, Cao X., 2015
Tet2 is required to resolve inflammation by recruiting Hdac2 to specifically repress IL-6., Zhang Q, Zhao K, Shen Q, Han Y, Gu Y, Li X, Zhao D, Liu Y, Wang C, Zhang X, Su X, Liu J, Ge W, Levine RL, Li N, Cao X., 2015
Rhbdd3 controls autoimmunity by suppressing the production of IL-6 by dendritic cells via K27-linked ubiquitination of the regulator NEMO., Liu J, Han C, Xie B, Wu Y, Liu S, Chen K, Xia M, Zhang Y, Song L, Li Z, Zhang T, Ma F, Wang Q, Wang J, Deng K, Zhuang Y, Wu X, Yu Y, Xu T, Cao X., 2014
Small GTPase RBJ mediates nuclear entrapment of MEK1/MEK2 in tumor progression., Chen T, Yang M, Yu Z, Tang S, Wang C, Zhu X, Guo J, Li N, Zhang W, Hou J, Liu H, Han C, Liu Q, Gu Y, Qian C, Wan T, Cui L, Zhu M, Zheng W, Cao X., 2014
Hepatic RIG-I predicts survival and interferon-α therapeutic response in hepatocellular carcinoma., Hou J, Zhou Y, Zheng Y, Fan J, Zhou W, Ng IO, Sun H, Qin L, Qiu S, Lee JM, Lo CM, Man K, Yang Y, Yang Y, Yang Y, Zhang Q, Zhu X, Li N, Wang Z, Ding G, Zhuang SM, Zheng L, Luo X, Xie Y, Liang A, Wang Z, Zhang M, Xia Q, Liang T, Yu Y, Cao X., 2014
The STAT3-binding long noncoding RNA lnc-DC controls human dendritic cell differentiation., Wang P, Xue Y, Han Y, Lin L, Wu C, Xu S, Jiang Z, Xu J, Liu Q, Cao X., 2014
Induction of Siglec-G by RNA viruses inhibits the innate immune response by promoting RIG-I degradation., Chen W, Han C, Xie B, Hu X, Yu Q, Shi L, Wang Q, Li D, Wang J, Zheng P, Liu Y, Cao X., 2013
Histone Methyltransferase Ash1l Suppresses Interleukin-6 Production and Inflammatory Autoimmune Diseases by Inducing the Ubiquitin-Editing Enzyme A20., Xia M, Liu J, Wu X, Liu S, Li G, Han C, Song L, Li Z, Wang Q, Wang J, Xu T, Cao X., 2013
Constitutive MHC class I molecules negatively regulate TLR-triggered inflammatory responses via the Fps-SHP-2 pathway., Xu S, Liu X, Bao Y, Zhu X, Han C, Zhang P, Zhang X, Li W, Cao X., 2012
Intracellular MHC class II molecules promote TLR-triggered innate immune responses by maintaining Btk activation., Liu X, Zhan Z, Li D, Xu L, Ma F, Zhang P, Yao H, Cao X., 2011
The microRNA miR-29 controls innate and adaptive immune responses to intracellular bacterial infection by targeting interferon-γ., Ma F, Xu S, Liu X, Zhang Q, Xu X, Liu M, Hua M, Li N, Yao H, Cao X., 2011
Identification of miRNomes in human liver and hepatocellular carcinoma reveals miR-199a/b-3p as a therapeutic target for hepatocellular carcinoma., Hou J, Lin L, Zhou W, Wang Z, Ding G, Dong Q, Qin L, Wu X, Zheng Y, Yang Y, Tian W, Zhang Q, Wang C, Zhang Q, Zhuang S, Zheng L, Liang A, Tao W, and Cao X., 2011
The cytosolic nucleic acid sensor LRRFIP1 mediates the production of type I interferon via a beta-catenin-dependent pathway., Yang P, An H, Liu X, Wen M, Zheng Y, Rui Y, Cao X., 2010
Integrin CD11b negatively regulates TLR-triggered inflammatory response by activating Syk and promoting MyD88 and TRIF degradation via cbl-b., Han C, Jin J, Xu S, Liu H, Li N, Cao X., 2010
The E3 ubiquitin ligase Nrdp1 preferentially promotes TLR-mediated type I interferon production., Wang C, Chen T, Zhang J, Yang M, Li N, Xu X, Cao X., 2009
Phosphatase SHP-1 promotes TLR- and RIG-I-activated production of type I interferon by inhibiting kinase IRAK-1., An H, Hou J, Zhou J, Zhao Y, Xu H, Zheng Y, Yu Y, Liu S and Cao X., 2008
