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Yue Huang
Basic Medical Sciences
Peking Union Medical College
Beijing
Language: Chinese, English
Stem Cells
Differentiation
Development
Genetic Therapy
Hereditary Diseases
Aneuploidy
Tumorigenesis
Non-Coding Rna
Epigenetics
Pluripotency
Areas of Focus
- Stem Cell Differentiation and Development
- Genetic Therapy for Hereditary Diseases
- Aneuploidy and Tumorigenesis
- Non-coding RNA and Epigenetic Factors in Pluripotency
Work Experience
- 2000-2004 - Assistant Researcher at Biochemistry Department, Peking Union Medical College
- 2001-2002 - Visiting Scholar at Biochemistry Department, University of Hong Kong
- 2004-2009 - Visiting Scholar and Postdoctoral Researcher at Sanger Institute, Cambridge, UK
- 2009-present - Researcher and Specially Appointed Professor at Medical Genetics Department, Peking Union Medical College
Academic Background & Achievements
- 1994 - Bachelor's Degree in Molecular Biology: Jilin University
- 1997 - Master's Degree in Molecular Genetics: Sun Yat-sen University
- 2000 - PhD in Biochemistry and Molecular Biology: Peking Union Medical College
- 2010 - Selected for the Ministry of Education's New Century Excellent Talents Support Program
Publications
- Aneuploid embryonic stem cells drive teratoma metastasis, Xiao R, Xu D, Zhang M, Chen Z, Cheng L, Du S, Lu M, Zhou T, Li R, Bai F, Huang Y, 2024
- The effect of trisomic chromosomes on spatial genome organization and global transcription in embryonic stem cells, Li M, Yang J, Xiao R, Liu Y, Hu J, Li T, Wu P, Zhang M, Huang Y, Sun Y, Li C, 2024
- Klf4 methylated by Prmt1 restrains the commitment of primitive endoderm, Zuo ZY, Yang GH, Wang HY, Liu SY, Zhang YJ, Cai Y, Chen F, Dai H, Xiao Y, Cheng MB, Huang Y, Zhang Y, 2022
- hnRNPLL controls pluripotency exit of embryonic stem cells by modulating alternative splicing of Tbx3 and Bptf, Wang X, Ping C, Tan P, Wang D, Yu J, Ma Y, Huang Y, 2021
- A genetic screen identifies Etl4-deficiency capable of stabilizing the haploidy in embryonic stem cells, Zhang GZ, Li XW, Sun Y, Wang X, Liu G, Huang Y, 2021
- CDK5RAP3 Deficiency Restrains Liver Regeneration after Partial Hepatectomy Triggering Endoplasmic Reticulum Stress, Yang S, Yang R, Wang H, Huang Y, Jia Y, 2020
- CDK5RAP3, a UFL1 substrate adaptor, is crucial for liver development, Rui Yang, Huanmin Wang, Yuyan Jia, Yue Huang, 2019
- Arrayed mutant haploid embryonic stem cell libraries facilitate phenotype-driven genetic screens, Gaung Liu, Xue Wang, Yufang Liu, Meili Zhang, Tao Cai, Zhirong Shen, Yuyan Jia and Yue Huang, 2017
- Aneuploid embryonic stem cells exhibit impaired differentiation and increased neoplastic potential, Meili Zhang, Li Cheng, Yuyan Jia, Guang Liu, Cuiping Li, Shuhui Song, Allan Bradley & Yue Huang, 2016
- Functional screen reveals essential roles of miR-27a/24 in differentiation of embryonic stem cells, Yanni Ma, Nan Yao, Guang Liu, Yue Huang & Jia Yu, 2015
- Rapidly Generating Knockout Mice from H19-Igf2 Engineered Androgenetic Haploid Embryonic Stem Cells, Meili Zhang, Yufang Liu, Guang Liu, Xin Li, Yuyan Jia, Lihong Sun, Liu Wang, Qi Zhou & Yue Huang, 2015
- Isolation of homozygous mutant mouse embryonic stem cells using a dual selection system, Yue Huang, Stephen J. Pettitt, Ge Guo, et al, 2012
- A PiggyBac transposon-based genome-wide library of insertionally mutated Blm-deficient murine ES cells, Wei Wang, Allan Bradley and Yue Huang, 2009
Awards
- 2010 - Selected for the Ministry of Education's New Century Excellent Talents Support Program
