Professor | Yue Huang | Asia Growth Partners

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Name	Yue Huang
Contact Information	huangyue@pumc.edu.cn
Language ability	Chinese, English
Province	Beijing

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Name

Yue Huang

Contact Information

huangyue@pumc.edu.cn

Language ability

Chinese, English

Province

Beijing

University/Lab Affiliation and Title	Peking Union Medical College
Faculty	Basic Medical Sciences
Academic Background & Achievements	1994 - Bachelor's Degree in Molecular Biology: Jilin University 1997 - Master's Degree in Molecular Genetics: Sun Yat-sen University 2000 - PhD in Biochemistry and Molecular Biology: Peking Union Medical College 2010 - Selected for the Ministry of Education's New Century Excellent Talents Support Program
Work Experience	2000-2004 - Assistant Researcher at Biochemistry Department, Peking Union Medical College 2001-2002 - Visiting Scholar at Biochemistry Department, University of Hong Kong 2004-2009 - Visiting Scholar and Postdoctoral Researcher at Sanger Institute, Cambridge, UK 2009-present - Researcher and Specially Appointed Professor at Medical Genetics Department, Peking Union Medical College
Awards	2010 - Selected for the Ministry of Education's New Century Excellent Talents Support Program

University/Lab Affiliation and Title

Peking Union Medical College

Faculty

Basic Medical Sciences

Academic Background & Achievements

1994 - Bachelor's Degree in Molecular Biology: Jilin University
1997 - Master's Degree in Molecular Genetics: Sun Yat-sen University
2000 - PhD in Biochemistry and Molecular Biology: Peking Union Medical College
2010 - Selected for the Ministry of Education's New Century Excellent Talents Support Program

Work Experience

2000-2004 - Assistant Researcher at Biochemistry Department, Peking Union Medical College
2001-2002 - Visiting Scholar at Biochemistry Department, University of Hong Kong
2004-2009 - Visiting Scholar and Postdoctoral Researcher at Sanger Institute, Cambridge, UK
2009-present - Researcher and Specially Appointed Professor at Medical Genetics Department, Peking Union Medical College

Awards

2010 - Selected for the Ministry of Education's New Century Excellent Talents Support Program

Areas of Focus	Stem Cell Differentiation and Development Genetic Therapy for Hereditary Diseases Aneuploidy and Tumorigenesis Non-coding RNA and Epigenetic Factors in Pluripotency
Publications	Aneuploid embryonic stem cells drive teratoma metastasis, Xiao R, Xu D, Zhang M, Chen Z, Cheng L, Du S, Lu M, Zhou T, Li R, Bai F, Huang Y, 2024 The effect of trisomic chromosomes on spatial genome organization and global transcription in embryonic stem cells, Li M, Yang J, Xiao R, Liu Y, Hu J, Li T, Wu P, Zhang M, Huang Y, Sun Y, Li C, 2024 Klf4 methylated by Prmt1 restrains the commitment of primitive endoderm, Zuo ZY, Yang GH, Wang HY, Liu SY, Zhang YJ, Cai Y, Chen F, Dai H, Xiao Y, Cheng MB, Huang Y, Zhang Y, 2022 hnRNPLL controls pluripotency exit of embryonic stem cells by modulating alternative splicing of Tbx3 and Bptf, Wang X, Ping C, Tan P, Wang D, Yu J, Ma Y, Huang Y, 2021 A genetic screen identifies Etl4-deficiency capable of stabilizing the haploidy in embryonic stem cells, Zhang GZ, Li XW, Sun Y, Wang X, Liu G, Huang Y, 2021 CDK5RAP3 Deficiency Restrains Liver Regeneration after Partial Hepatectomy Triggering Endoplasmic Reticulum Stress, Yang S, Yang R, Wang H, Huang Y, Jia Y, 2020 CDK5RAP3, a UFL1 substrate adaptor, is crucial for liver development, Rui Yang, Huanmin Wang, Yuyan Jia, Yue Huang, 2019 Arrayed mutant haploid embryonic stem cell libraries facilitate phenotype-driven genetic screens, Gaung Liu, Xue Wang, Yufang Liu, Meili Zhang, Tao Cai, Zhirong Shen, Yuyan Jia and Yue Huang, 2017 Aneuploid embryonic stem cells exhibit impaired differentiation and increased neoplastic potential, Meili Zhang, Li Cheng, Yuyan Jia, Guang Liu, Cuiping Li, Shuhui Song, Allan Bradley & Yue Huang, 2016 Functional screen reveals essential roles of miR-27a/24 in differentiation of embryonic stem cells, Yanni Ma, Nan Yao, Guang Liu, Yue Huang & Jia Yu, 2015 Rapidly Generating Knockout Mice from H19-Igf2 Engineered Androgenetic Haploid Embryonic Stem Cells, Meili Zhang, Yufang Liu, Guang Liu, Xin Li, Yuyan Jia, Lihong Sun, Liu Wang, Qi Zhou & Yue Huang, 2015 Isolation of homozygous mutant mouse embryonic stem cells using a dual selection system, Yue Huang, Stephen J. Pettitt, Ge Guo, et al, 2012 A PiggyBac transposon-based genome-wide library of insertionally mutated Blm-deficient murine ES cells, Wei Wang, Allan Bradley and Yue Huang, 2009

Areas of Focus

Stem Cell Differentiation and Development
Genetic Therapy for Hereditary Diseases
Aneuploidy and Tumorigenesis
Non-coding RNA and Epigenetic Factors in Pluripotency

Publications

Aneuploid embryonic stem cells drive teratoma metastasis, Xiao R, Xu D, Zhang M, Chen Z, Cheng L, Du S, Lu M, Zhou T, Li R, Bai F, Huang Y, 2024
The effect of trisomic chromosomes on spatial genome organization and global transcription in embryonic stem cells, Li M, Yang J, Xiao R, Liu Y, Hu J, Li T, Wu P, Zhang M, Huang Y, Sun Y, Li C, 2024
Klf4 methylated by Prmt1 restrains the commitment of primitive endoderm, Zuo ZY, Yang GH, Wang HY, Liu SY, Zhang YJ, Cai Y, Chen F, Dai H, Xiao Y, Cheng MB, Huang Y, Zhang Y, 2022
hnRNPLL controls pluripotency exit of embryonic stem cells by modulating alternative splicing of Tbx3 and Bptf, Wang X, Ping C, Tan P, Wang D, Yu J, Ma Y, Huang Y, 2021
A genetic screen identifies Etl4-deficiency capable of stabilizing the haploidy in embryonic stem cells, Zhang GZ, Li XW, Sun Y, Wang X, Liu G, Huang Y, 2021
CDK5RAP3 Deficiency Restrains Liver Regeneration after Partial Hepatectomy Triggering Endoplasmic Reticulum Stress, Yang S, Yang R, Wang H, Huang Y, Jia Y, 2020
CDK5RAP3, a UFL1 substrate adaptor, is crucial for liver development, Rui Yang, Huanmin Wang, Yuyan Jia, Yue Huang, 2019
Arrayed mutant haploid embryonic stem cell libraries facilitate phenotype-driven genetic screens, Gaung Liu, Xue Wang, Yufang Liu, Meili Zhang, Tao Cai, Zhirong Shen, Yuyan Jia and Yue Huang, 2017
Aneuploid embryonic stem cells exhibit impaired differentiation and increased neoplastic potential, Meili Zhang, Li Cheng, Yuyan Jia, Guang Liu, Cuiping Li, Shuhui Song, Allan Bradley & Yue Huang, 2016
Functional screen reveals essential roles of miR-27a/24 in differentiation of embryonic stem cells, Yanni Ma, Nan Yao, Guang Liu, Yue Huang & Jia Yu, 2015
Rapidly Generating Knockout Mice from H19-Igf2 Engineered Androgenetic Haploid Embryonic Stem Cells, Meili Zhang, Yufang Liu, Guang Liu, Xin Li, Yuyan Jia, Lihong Sun, Liu Wang, Qi Zhou & Yue Huang, 2015
Isolation of homozygous mutant mouse embryonic stem cells using a dual selection system, Yue Huang, Stephen J. Pettitt, Ge Guo, et al, 2012
A PiggyBac transposon-based genome-wide library of insertionally mutated Blm-deficient murine ES cells, Wei Wang, Allan Bradley and Yue Huang, 2009

Stem Cells Differentiation Development Genetic Therapy Hereditary Diseases Aneuploidy Tumorigenesis Non-Coding Rna Epigenetics Pluripotency

Jing Liang - Peking University

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