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Yu Yu
Basic Medical Sciences
Peking University
Beijing
Language: Chinese, English
Epigenetics
Tumor
Development
Progression
Post-Translational
Modifications
Metastasis
Regulation
Cancer
Mechanisms
Areas of Focus
- Epigenetic mechanisms of tumor development and progression
- Post-translational modifications in development and tumor metastasis
Academic Background & Achievements
- Hosted multiple research projects including National Natural Science Foundation of China and Beijing Natural Science Foundation
- Published over 20 SCI papers
Publications
- The DNMT1-PAS1-PH20 axis drives breast cancer growth and metastasis, Yenan Fu, Xi Zhang, Xiao Liu, Peng Wang, Wenhui Chu, Wei Zhao, Yunling Wang, Guangbiao Zhou, Yu Yu*, Hongquan Zhang*, 2022
- The EZH2–PHACTR2–AS1–Ribosome Axis induces Genomic Instability and Promotes Growth and Metastasis in Breast Cancer, Wenhui Chu, Xi Zhang, Lihua Qi, Yenan Fu, Peng Wang, Wei Zhao, Juan Du, Jing Zhang, Jun Zhan, Yunling Wang, Wei-Guo Zhu, Yu Yu*, Hongquan Zhang*, 2020
- Kindlin-2 suppresses transcription factor GATA4 through interaction with SUV39H1 to attenuate hypertrophy, Lihua Qi, Xiaochun Chi, Xueqian Feng, Shengchang Zhang, Junzhou Wu, Yao Song, Youyi Zhang, Wei kong, Yu Yu*, Hongquan Zhang*, 2019
- Kindlin-2 interacts with and stabilizes DNMT1 to promote breast cancer development, Peng Wang, Wenhui Chu, Xi Zhang, Bing Li, Junzhou Wu, Lihua Qi, Yu Yu*, Hongquan Zhang*, 2018
- Kindlin-2 forms a transcriptional complex with β-catenin and TCF4 to enhance Wnt signaling, Yu Yu, Junzhou Wu, Yunling Wang, Ting Zhao, Bo Ma, Yuqing Liu, Weigang Fang, Wei-Guo Zhu & Hongquan Zhang, 2012
- Kindlin 2 promotes breast cancer invasion via epigenetic silencing of the microRNA200 gene family, Yu Yu, Junzhou Wu, Lizhao Guan, Lihua Qi, Yan Tang, Bo Ma, Jun Zhan, Yunling Wang, Weigang Fang, and Hongquan Zhang, 2013
Awards
- Second Prize of Chinese Medical Science and Technology Award (Fifth Contributor)
- Beijing University Outstanding Talent Award Plan
- Beijing Colleges 'Young Talent' Plan
