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Personal Information

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Yu Yu
yuyu@bjmu.edu.cn
Chinese, English
Beijing

Academic Information

Peking University
Basic Medical Sciences
  • Hosted multiple research projects including National Natural Science Foundation of China and Beijing Natural Science Foundation
  • Published over 20 SCI papers
  • Second Prize of Chinese Medical Science and Technology Award (Fifth Contributor)
  • Beijing University Outstanding Talent Award Plan
  • Beijing Colleges 'Young Talent' Plan

Research

Epigenetic mechanisms of tumor development and progression
Post-translational modifications in development and tumor metastasis
  • The DNMT1-PAS1-PH20 axis drives breast cancer growth and metastasis, Yenan Fu, Xi Zhang, Xiao Liu, Peng Wang, Wenhui Chu, Wei Zhao, Yunling Wang, Guangbiao Zhou, Yu Yu*, Hongquan Zhang*, 2022
  • The EZH2–PHACTR2–AS1–Ribosome Axis induces Genomic Instability and Promotes Growth and Metastasis in Breast Cancer, Wenhui Chu, Xi Zhang, Lihua Qi, Yenan Fu, Peng Wang, Wei Zhao, Juan Du, Jing Zhang, Jun Zhan, Yunling Wang, Wei-Guo Zhu, Yu Yu*, Hongquan Zhang*, 2020
  • Kindlin-2 suppresses transcription factor GATA4 through interaction with SUV39H1 to attenuate hypertrophy, Lihua Qi, Xiaochun Chi, Xueqian Feng, Shengchang Zhang, Junzhou Wu, Yao Song, Youyi Zhang, Wei kong, Yu Yu*, Hongquan Zhang*, 2019
  • Kindlin-2 interacts with and stabilizes DNMT1 to promote breast cancer development, Peng Wang, Wenhui Chu, Xi Zhang, Bing Li, Junzhou Wu, Lihua Qi, Yu Yu*, Hongquan Zhang*, 2018
  • Kindlin-2 forms a transcriptional complex with β-catenin and TCF4 to enhance Wnt signaling, Yu Yu, Junzhou Wu, Yunling Wang, Ting Zhao, Bo Ma, Yuqing Liu, Weigang Fang, Wei-Guo Zhu & Hongquan Zhang, 2012
  • Kindlin 2 promotes breast cancer invasion via epigenetic silencing of the microRNA200 gene family, Yu Yu, Junzhou Wu, Lizhao Guan, Lihua Qi, Yan Tang, Bo Ma, Jun Zhan, Yunling Wang, Weigang Fang, and Hongquan Zhang, 2013
Keywords
Epigenetics Tumor Development Progression Post-Translational Modifications Metastasis Regulation Cancer Mechanisms
Related Professors
Shang Yongfeng - Peking University
Area of Focus
Epigenetics | Gene Transcription | Regulation | Breast Cancer | Endometrial Cancer | Molecular Mechanisms | Cancer Development | Transcriptional Complexes | Gene Promoters | Therapeutic Targets
Xiaojuan Du - Peking University
Area of Focus
Tumor | Proteins | Cell Division | Metabolism | Drug Resistance | Metastasis | Dna Damage | Acetylation | Autophagy | Microtubule
Genze Shao - Peking University
Area of Focus
Brca1 | Tumor Suppressor | Gene | Breast Cancer | Ovarian Cancer | Dna Damage | Cell Cycle | Molecular Mechanisms | Protein Degradation | Cancer Research | Metastasis | K63 Ubiquitination | Chromatin Remodeling | Epigenetics | Rnf8 | Tumor Progression | Molecular Biology | Cancer Therapy | Protein Interactions | Biomarkers | Early Diagnosis | Therapeutic Evaluation | Prognosis | Serum Markers | Tumor Specific | Sensitive Markers | Cancer Detection | Clinical Applications | Molecular Diagnostics | Cell Division | Mitosis | Spindle Assembly | Checkpoint Mechanisms | Protein Ubiquitination | Deubiquitinating Enzymes | Genetic Stability
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