Professor | Xiang Lv | Asia Growth Partners

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Name	Xiang Lv
Language ability	Chinese, English
Province	Beijing

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Name

Xiang Lv

Language ability

Chinese, English

Province

Beijing

University/Lab Affiliation and Title	Peking Union Medical College
Faculty	Basic Medical Sciences
Academic Background & Achievements	1991-1995 Bachelor of Science: Shandong University 1995-1998 Master of Science: Institute of Developmental Biology, Chinese Academy of Sciences 1999-2002 PhD in Biochemistry and Molecular Biology: Peking Union Medical College 2002 First Prize of Chinese Medical Science and Technology Award
Work Experience	Post-2002 - Assistant Researcher, Associate Researcher: Peking Union Medical College 2004.11-2006.7 - Postdoctoral Research: INSERM U36, France 2013.7 - Researcher: Department of Biochemistry 2015.10 - Group Leader: Department of Pathophysiology
Awards	2002: First Prize of Chinese Medical Science and Technology Award 2003: Young Scientist travel fellowship for the XIX International Congress of Biochemistry and Molecular Biology 2004-2005: Fellowship from Fondation Franco-Chinois pour Science et ses Applications (FFCSA) 2006: Fellowship from Fondation Treilles 2006: European commission Marie Curie Actions Scholarship (European School of Haematology)

University/Lab Affiliation and Title

Peking Union Medical College

Faculty

Basic Medical Sciences

Academic Background & Achievements

1991-1995 Bachelor of Science: Shandong University
1995-1998 Master of Science: Institute of Developmental Biology, Chinese Academy of Sciences
1999-2002 PhD in Biochemistry and Molecular Biology: Peking Union Medical College
2002 First Prize of Chinese Medical Science and Technology Award

Work Experience

Post-2002 - Assistant Researcher, Associate Researcher: Peking Union Medical College
2004.11-2006.7 - Postdoctoral Research: INSERM U36, France
2013.7 - Researcher: Department of Biochemistry
2015.10 - Group Leader: Department of Pathophysiology

Awards

2002: First Prize of Chinese Medical Science and Technology Award
2003: Young Scientist travel fellowship for the XIX International Congress of Biochemistry and Molecular Biology
2004-2005: Fellowship from Fondation Franco-Chinois pour Science et ses Applications (FFCSA)
2006: Fellowship from Fondation Treilles
2006: European commission Marie Curie Actions Scholarship (European School of Haematology)

Areas of Focus	Multilayered gene expression regulation in hematopoietic differentiation 3D chromatin conformation and transcriptional regulation mechanisms
Publications	Long noncoding RNA LINC00305 promotes inflammation by activating the AHRR-NF-κB pathway in human monocytes., Dan-Dan Zhang, Wen-Tian Wang, Jian Xiong, Xue-Min Xie, Shen-Shen Cui, Zhi-Guo Zhao, Mulin Jun Li, Zhu-Qin Zhang, De-Long Hao, Xiang Zhao, Yong-Jun Li, Jun-Wen Wang, Hou-Zao Chen, Xiang Lv, De-pei Liu, 2017 Netrin-1 suppresses the MEK/ERK pathway and ITGB4 in pancreatic cancer., Xi-Zhou An, Zhi-Guo Zhao, Yu-Xuan Luo, Ran Zhang, Xiao-Qiang Tang, DeLong Hao, Xiang Zhao, Xiang Lv, De-Pei Liu, 2016 The long noncoding RNA Gm15055 represses Hoxa gene expression by recruiting PRC2 to the gene cluster., Guo-You Liu, Guang-Nian Zhao, Xiao-Feng Chen, De-Long Hao, Xiang Zhao, Xiang Lv, De-pei Liu, 2016 CTCF controls HOXA cluster silencing and mediates PRC2-repressive higher-order chromatin structure in NT2/D1 cells., Miao Xu, Guan-gnian Zhao, Xiang Lv, Guo-you Liu, Lily Yan Wang, De-Long Hao, Jun-wen Wang, De-Pei Liu, Chih-Chuan Liang, 2014 PML4 facilitates erythroid differentiation by enhancing the transcriptional activity of GATA-1., Jie Wu, Li-Quan Zhou, Wei Yu, Zhi-Guo Zhao, Xue-Min Xie, Wen-Tian Wang, Jian Xiong, Man Li, Zheng Xue, Xing Wang, Peng Zhang, Bei-Bei Mao, De-Long Hao, Xiang Lv, De-Pei Liu, 2014 The AT-rich DNA-binding protein SATB2 promotes expression and physical association of human Gγ- and Aγ-globin genes., Li-Quan Zhou, Jie Wu, Wen-Tian Wang, Guang-Nian Zhao, Wei Yu, Peng Zhang, Jian Xiong, Man Li, Zheng Xue, Xing Wang, Zhi-Chen Guo, Xiang Lv, De-Pei Liu, 2012 SIRT1 deacetylates SATB1 to facilitate MARHS2- MARε interaction and promote ε-globin expression., Zheng Xue, Xiang Lv, Wei Song, Xing Wang, Guang-Nian Zhao, Wen-Tian Wang, Jian Xiong, Bei-Bei Mao, Wei Yu, Ben Yang, Jie Wu, Li-Quan Zhou, De-Long Hao, Wen-Ji Dong, De-Pei Liu, Chih-Chuan Liang, 2012 Sirt1 deacetylates c-Myc and promotes c-Myc/Max association., Beibei Mao, Guowei Zhao, Xiang Lv, Hou-Zao Chen, Zheng Xue, Ben Yang, De-Pei Liu, Chih-Chuan Liang, 2011 Modulations of hMOF autoacetylation by SIRT1 regulate hMOF recruitment and activities on the chromatin., Lu Lu, Lei Li, Xiang Lv, Xue-Song Wu, De-Pei Liu, Chih-Chuan Liang, 2011 Positive Regulation of Hepatic miR-122 Expression by HNF4α., Zhen-Ya Li, Yang Xi, Wen-Nan Zhu, Chao-Zeng, Zhu-Qin Zhang, Zhi-Chen Guo, De-Long Hao, Guang Liu, Lei Feng, Hou-Zao Chen, Feng Chen, Xiang Lv, De-Pei Liu, Chih-Chuan Liang, 2011 Activation of the UNC5B receptor by Netrin-1 inhibits neovascularization., Bruno Larrivée, Catarina Freitas, Marc Trombe, Xiang Lv, Benjamin DeLafarge, Li Yuan, Karine Bouvrée, Christiane Bréant, Françoise Bono, Filip Claes, Monica Autiero, Peter armeliet, Marc Tessier-Lavigne and Anne Eichmann, 2007

Areas of Focus

Multilayered gene expression regulation in hematopoietic differentiation
3D chromatin conformation and transcriptional regulation mechanisms

Publications

Long noncoding RNA LINC00305 promotes inflammation by activating the AHRR-NF-κB pathway in human monocytes., Dan-Dan Zhang, Wen-Tian Wang, Jian Xiong, Xue-Min Xie, Shen-Shen Cui, Zhi-Guo Zhao, Mulin Jun Li, Zhu-Qin Zhang, De-Long Hao, Xiang Zhao, Yong-Jun Li, Jun-Wen Wang, Hou-Zao Chen, Xiang Lv, De-pei Liu, 2017
Netrin-1 suppresses the MEK/ERK pathway and ITGB4 in pancreatic cancer., Xi-Zhou An, Zhi-Guo Zhao, Yu-Xuan Luo, Ran Zhang, Xiao-Qiang Tang, DeLong Hao, Xiang Zhao, Xiang Lv, De-Pei Liu, 2016
The long noncoding RNA Gm15055 represses Hoxa gene expression by recruiting PRC2 to the gene cluster., Guo-You Liu, Guang-Nian Zhao, Xiao-Feng Chen, De-Long Hao, Xiang Zhao, Xiang Lv, De-pei Liu, 2016
CTCF controls HOXA cluster silencing and mediates PRC2-repressive higher-order chromatin structure in NT2/D1 cells., Miao Xu, Guan-gnian Zhao, Xiang Lv, Guo-you Liu, Lily Yan Wang, De-Long Hao, Jun-wen Wang, De-Pei Liu, Chih-Chuan Liang, 2014
PML4 facilitates erythroid differentiation by enhancing the transcriptional activity of GATA-1., Jie Wu, Li-Quan Zhou, Wei Yu, Zhi-Guo Zhao, Xue-Min Xie, Wen-Tian Wang, Jian Xiong, Man Li, Zheng Xue, Xing Wang, Peng Zhang, Bei-Bei Mao, De-Long Hao, Xiang Lv, De-Pei Liu, 2014
The AT-rich DNA-binding protein SATB2 promotes expression and physical association of human Gγ- and Aγ-globin genes., Li-Quan Zhou, Jie Wu, Wen-Tian Wang, Guang-Nian Zhao, Wei Yu, Peng Zhang, Jian Xiong, Man Li, Zheng Xue, Xing Wang, Zhi-Chen Guo, Xiang Lv, De-Pei Liu, 2012
SIRT1 deacetylates SATB1 to facilitate MARHS2- MARε interaction and promote ε-globin expression., Zheng Xue, Xiang Lv, Wei Song, Xing Wang, Guang-Nian Zhao, Wen-Tian Wang, Jian Xiong, Bei-Bei Mao, Wei Yu, Ben Yang, Jie Wu, Li-Quan Zhou, De-Long Hao, Wen-Ji Dong, De-Pei Liu, Chih-Chuan Liang, 2012
Sirt1 deacetylates c-Myc and promotes c-Myc/Max association., Beibei Mao, Guowei Zhao, Xiang Lv, Hou-Zao Chen, Zheng Xue, Ben Yang, De-Pei Liu, Chih-Chuan Liang, 2011
Modulations of hMOF autoacetylation by SIRT1 regulate hMOF recruitment and activities on the chromatin., Lu Lu, Lei Li, Xiang Lv, Xue-Song Wu, De-Pei Liu, Chih-Chuan Liang, 2011
Positive Regulation of Hepatic miR-122 Expression by HNF4α., Zhen-Ya Li, Yang Xi, Wen-Nan Zhu, Chao-Zeng, Zhu-Qin Zhang, Zhi-Chen Guo, De-Long Hao, Guang Liu, Lei Feng, Hou-Zao Chen, Feng Chen, Xiang Lv, De-Pei Liu, Chih-Chuan Liang, 2011
Activation of the UNC5B receptor by Netrin-1 inhibits neovascularization., Bruno Larrivée, Catarina Freitas, Marc Trombe, Xiang Lv, Benjamin DeLafarge, Li Yuan, Karine Bouvrée, Christiane Bréant, Françoise Bono, Filip Claes, Monica Autiero, Peter armeliet, Marc Tessier-Lavigne and Anne Eichmann, 2007

Hematopoiesis Gene Expression Chromatin 3D Genome Transcription Regulation Differentiation Non-Coding Rna Nuclear Matrix Gene Clusters

Yongguang Tao - Central South University

Kuangyu Yen - Southern Medical University

Bo Wen - Chongqing Medical University

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