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Kuangyu Yen
Basic Medical Sciences
Southern Medical University
Guangdong
Language: Chinese, English
Gene Expression
Chromatin
Stem Cells
Disease
Nucleosome Positioning
Genomics
Bioinformatics
Biochemical Systems
Hematopoietic Development
Transcriptional Network
Areas of Focus
- Transcription regulation
- Nucleosome
- Hematopoiesis
Work Experience
- 2005-2012 - Postdoctoral Researcher: University of Washington, Penn State University
- 2012-2014 - Research Assistant Professor: Penn State University
- 2014-present - Full-time Professor: Southern Medical University
Academic Background & Achievements
- 1998 - Bachelor of Science: National Taiwan University
- 2005 - PhD in Molecular Biology: University of Manchester
Publications
- Targeting of apoptosis gene loci by reprogramming factors leads to selective eradication of leukemia cells, Yajie Wang, Ting Lu, Guohuan Sun, Yawei Zheng, Shangda Yang, Hongyan Zhang, Sha Hao, Yanfeng Liu, Shihui Ma, Houyu Zhang, Yongxin Ru, Shaorong Gao, Kuangyu Yen, Hui Cheng, and Tao Cheng, 2019
- Asxl1 C-terminal mutation perturbs neutrophil differentiation in zebrafish, Fang X, Xu S, Zhang Y, Xu J, Huang Z, Liu W, Wang S, Yen K, Zhang W, 2021
- Prognostic prediction of cytogenetically normal acute myeloid leukemia based on a gene expression model, Yang L, Zhang H, Yang X, Lu T, Ma S, Cheng H, Yen K, Cheng T, 2021
- RUNX1 upregulates CENPE to promote leukemic cell proliferation, Liu S, Yang J, Sun G, Zhang Y, Cheng C, Xu J, Yen K, Lu T, 2021
- Genome-wide nucleosome specificity and function of chromatin remodellers in ES cells, de Dieuleveult, M, Yen K, Hmitou I, Depaux A, Boussouar F, Dargham DB, Jounier S, Humbertclaude H, Ribierre F, Baulard C, Farrell NP, Park B, Keime C, Carriere L, Merlivet S, Gut M, Gut I, Werner M, Deleuze JF, Olaso R, Aude JC, Chantalat S, Pugh BF and Gerard M, 2016
- Genome-wide structural integration of SWR-C and INO80 chromatin remodelers at +1 nucleosomes, Yen K, Vinayachandran V and Pugh BF, 2013
- Genome-wide nucleosome specificity and directionality of chromatin remodelers, Yen K, Vinayachandran V, Batta K, Koerber RT and Pugh BF, 2012
Awards
- 2015 - National High-level Talent
- 2015 - National Natural Science Foundation Excellent Youth Project
