Areas of Focus
- Statistical methods development for multi-omics data
- Application in cancer research
Work Experience
- 2013-2015 - Dana-Farber Cancer Institute - Postdoctoral Researcher
- 2015-2020 - Dana-Farber Cancer Institute - Research Associate
- 2020-2021 - Dana-Farber Cancer Institute - Scientist
- 2021-present - Peking University, Precision Medicine Multi-Omics Research Center - Researcher
Academic Background & Achievements
- 2001-2005 Bachelor: Beijing Normal University
- 2007-2012 PhD: Institute of Genetics and Developmental Biology, Chinese Academy of Sciences
Publications
- Topological isolation of developmental regulators in mammalian genomes, Wu HJ, Landshammer A, Stamenova E, Bolondi A, Kretzmer H, Meissner A, Michor F, 2021
- A computational strategy to adjust for copy number in tumor Hi-C data, Wu HJ, Michor F, 2016
- KDM5 histone demethylase activity links cellular transcriptomic heterogeneity to therapeutic resistance, Hinohara K, Wu HJ, Vigneau S, McDonald TO, Igarashi KJ, Yamamoto KN, Madsen T, Fassl A, Egri SB, Papanastasiou M, Ding L, Peluffo G, Cohen O, Kales SC, Lal-Nag M, Rai G, Maloney DJ, Jadhav A, Simeonov A, Wagle N, Brown M, Meissner A, Sicinski P, Jaffe JD, Jeselsohn R, Gimelbrandt AA, Michor F, Polyak K, 2018
- Synthetic lethal and resistance interactions with BET bromodomain inhibitors in triple-negative breast cancer, Shu S, Wu HJ, Ge JY, Zeid R, Harris IS, Jovanovic B, Murphy K, Wang B, Qiu X, Endress JE, Reyes J, Lim K, Font-Tello A, Syamala S, Xiao T, Chilamakuri CSR, Papachristou EK, D'Santos C, Anand J, Hinohara K, Li W, McDonald TO, Luoma A, Modiste RJ, Nguyen Q-D, Michel B, Cejas P, Kadoch C, Jaffe JD, Wucherpfennig KW, Qi J, Liu XS, Long H, Brown M, Carroll JS, Brugge JS, Bradner J, Michor F, Polyak K, 2020
- A PDGFRalpha-driven mouse model of glioblastoma reveals a stathmin1-mediated mechanism of sensitivity to vinblastine, Jun HJ, Appleman VA, Wu HJ, Rose CM, Pineda JJ, Yeo AT, Delcuze B, Lee C, Gyuris A, Zhu H, Woolfenden S, Bronisz A, Nakano I, Chiocca EA, Bronson RT, Ligon KL, Sarkaria JN, Gygi SP, Michor F, Mitchison TJ, Charest A, 2018