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Jun Yang
jy270@ibms.pumc.edu.cn
Chinese, English
Beijing
Peking Union Medical College
Basic Medical Sciences
  • 2014 - Present - Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences - Researcher
  • 2016: Outstanding Researcher of the Institute
  • 2009: Pfizer Pulmonary Vascular Disease European Young Researcher Award First Prize
  • 2007: British Association of Lung Research-British Thoracic Society Young Investigator First Prize
BMP signaling pathways in cardiopulmonary vascular diseases
Stem cell differentiation and cardiovascular cell research
Pathogenic mutations and stem cell drug screening
Inflammatory factors in pulmonary hypertension
  • A novel piperidine identified by stem cell based screening attenuates pulmonary arterial hypertension via regulating BMP2 and PTGS2 levels., Yanjiang Xing, Shuang Zhao, Qingxia Wei, Shiqiang Gong, Xin Zhao, Fang Zhou, Rafia AI-Lamki, Daniel Ortmann, Mingxia Du, Roger Pedersen, Guangdong Shang, Shuyi Si, Nicholas W Morrell, Jun Yang, 2018
  • Identification of Id genes as major functional targets of BMP signalling in endothelial cells: Potential for screening and therapy., Qingxia Wei, Shuang Zhao, Fang Zhou, Yanjiang Xing, Shiqiang Gong, Jiakuan Zhao, Rafia Ai-Lamki, Daniel Ortmann, Xin Zhao, Mingxia Du, Mariaestela Ortiz, Roger Pedersen, Shuyi Si, Morrell W Nicholas, Jun Yang, 2017
  • Endovascular treatment of ectopic bronchial artery aneurysm with brachiocephalic artery stent placement and coil embolization: A case report and literature review., Xiao Di, Dong Hua Ji, Yu Chen, Chang Wei Liu, Bao Liu, Jun Yang, 2016
  • Tumor necrosis factor receptor 2-signaling in CD133-expressing cells in renal clear cell carcinoma., Rafia S. Al-Lamki, Jun Wang, Jun Yang, Simon Pacey, Timothy Eisen, and John R. Bradley, 2016
  • Development of a high-throughput screening strategy for up-regulators of the OPG/RANKL ratio with the potential for anti-osteoporosis effects., Shiqiang Gong, Xiaowan Han, Xuehong Li, Xiaobo He, Jun Yang, Shuyi Si, 2016
  • Id proteins in the vasculature: from molecular biology to cardiopulmonary medicine., Jun Yang, Li X, Morrell NW, 2014
  • Sildenafil Potentiates Bone Morphogenetic Protein Signaling in Pulmonary Arterial Smooth Muscle Cells and in Experimental Pulmonary Hypertension., Jun Yang, Xiaohui Li, Changxin Wu, Astrid Weiss, Ralph Schermuly, and Nicholas Morrell, 2013
  • Id proteins are critical downstream effectors of BMP signaling in human pulmonary arterial smooth muscle cells., Jun Yang, Xiaohui Li, Mark Southwood, Ye Linying, Nicholas W. Morrell, 2013
  • TNF, Acting through inducibly expressed TNFR2, drives activation and cell cycle entry of c-kit+ cardiac stem cells in ischemic heart disease., Rafia S. Al-Lamki, Wanhua Lu, Jun Wang, Jun Yang, John R. Brdaley, 2013
  • Inhibition of overactive TGF-β signaling by prostacyclin analogues in pulmonary arterial hypertension (PAH)., Takeshi Ogo, H. M. Chowdhury, Jun Yang, Lu Long, Xiaohui Li, Yamila N. Torres Cleuren, Nicholas W Morrell, Ralph T. Schermuly, Richard C. Trembath and Md. Talat Nasim, 2013
  • Induction Of Id1 by Prostacyclin Analogues Inhibits Proliferation Of Pulmonary Artery Smooth Muscle Cells In Vitro And In Vivo., Jun Yang, Xiaohui Li, Rafia Al-Lamki, Andrew lever, Nicholas W. Morrell, 2010
  • Identification of a lysosomal pathway regulating degradation of the bone morphogenetic protein receptor type-II., Hannah J. Durrington, Paul D. Upton, Simon Hoer, Jessica Boname, Benjamin Dunmore, Jun Yang, Nicholas W. Morrell, 2010
  • Identification of BMP2 Up-regulators via High-Throughput Screening of a Synthetic and Natural Compound Library., Xue Li, Jun Yang, Xiaobo He, Zhangyong Yang, Yan Ding, Huayi Shao, Zhuorong Li, Yueqin Zhang, Shuyi Si, 2009
  • Evidence for Dysfunction of Endothelial Progenitors in Pulmonary Arterial Hypertension., Mark Toshner, Robert Voswinkel, Mark Southwood, Rafia Al-Lamki, Jun Yang, Nicholas W. Morrell et al., 2009
  • Mutations in BMPRII cause dysregulation of Id gene expression in pulmonary arterial smooth muscle cells: Implication for familial pulmonary arterial hypertension., Jun Yang, Rachel Davies, Lu Long, Xudong Yang, Paul Upton, Anastasia Sobolewski, Richard Trembath and Nick Morrell, 2008
  • Functional rescue of mutant bone morphogenetic protein receptor type II in pulmonary arterial hypertension., Anastasia Sobolewski, Nung Rudarakanchana, Jun Yang, Trina K. Jeffery, Richard Trembath, Nicholas W. Morrell, 2008
  • Study on a novel anti-osteoporosis drug screening model targeted on Cathepsin K., Jun Yang, Yueqin Zhang, 2004
  • The regulation of SMAD in TGF-β superfamily signaling pathway [review]., Jun Yang, Shuyi Si, Yueqin Zhang, 2003
  • The mechanism of Statins upregulate BMP-2 expression in osteoblast., Yan Ding, Jun Yang, Shuyi Si, Li Ruan, 2005
  • Study on the screening model of anti-osteoporosis drugs targeting on cathepsin L., Jun Yang, Bin Liu, Yueqin Zhang, 2002
  • Establishment and application of screening model for anti-bacteria drugs with lipoteichoic acid as a target., Jun Yang, Shan Cen, Yueqin Zhang, 2002
Bmp Signaling Cardiopulmonary Vascular Diseases Stem Cells Differentiation Cardiovascular Mutations Drug Screening Inflammation Pulmonary Hypertension

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