Professor | Tong Weimin | Asia Growth Partners

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Name	Tong Weimin
Contact Information	010-69156945\nwmtong(AT)ibms.pumc.edu.cn
Language ability	Chinese, English
Province	Beijing

Upload Avatar (500 x 500)

Name

Tong Weimin

Contact Information

010-69156945\nwmtong(AT)ibms.pumc.edu.cn

Language ability

Chinese, English

Province

Beijing

University/Lab Affiliation and Title	Peking Union Medical College
Faculty	Medical Laboratory Animal Research Institute
Academic Background & Achievements	1994-1996 PhD in Science: University of Vienna 1988-1991 Master's in Pathology: Bethune Medical University 1981-1986 Bachelor's in Forensic Medicine: China Medical University
Work Experience	2007-present - Chinese Academy of Medical Sciences & Peking Union Medical College - Professor 2000-2007 - IARC/WHO - Researcher 1997-2000 - IARC/WHO - Postdoctoral Researcher

University/Lab Affiliation and Title

Peking Union Medical College

Faculty

Medical Laboratory Animal Research Institute

Academic Background & Achievements

1994-1996 PhD in Science: University of Vienna
1988-1991 Master's in Pathology: Bethune Medical University
1981-1986 Bachelor's in Forensic Medicine: China Medical University

Work Experience

2007-present - Chinese Academy of Medical Sciences & Peking Union Medical College - Professor
2000-2007 - IARC/WHO - Researcher
1997-2000 - IARC/WHO - Postdoctoral Researcher

Areas of Focus	Epitranscriptomic RNA m6A methylation in major diseases Role of protein phosphatases in neurodevelopment and neurodegenerative diseases
Publications	Mic60 is essential to maintain mitochondrial integrity and to prevent encephalomyopathy., Dong, T., Zhang, Z.Q., Sun, L.H., Zhang, W., Zhu, Z., Lin, L., Yang, L., Lv, A., Liu, C., Li, Q., Yang, R.F., Zhang, X., Niu, Y., Chen, H.Z., Liu, D.P., and Tong, W.M., 2023 METTL3 regulates m(6)A methylation of PTCH1 and GLI2 in Sonic hedgehog signaling to promote tumor progression in SHH-medulloblastoma., Zhang, Z.W.#, Teng, X.#, Zhao, F.#, Ma, C.#, Zhang, J., Xiao, L.F., Wang, Y., Chang, M., Tian, Y., Li, C., Zhang, Z., Song, S., Tong, W.M. , Liu, P., and Niu, Y., 2022 Airway administration of bisphosphate and dexamethasone inhibits SARS-CoV-2 variant infection by targeting alveolar macrophages., Wang, Z.#, Zhou, Y.#, Bao, L., Li, D., Lv, J., Wang, D., Li, S., Liu, J., Qin, C., Tong, W.M., and Huang, B., 2022 Rare and misincorporated DNA N(6)-methyladenine is a hallmark of cytotoxic stresses for selectively stimulating the stemness and proliferation of glioblastoma cells., Lyu, C.#, Niu, Y.#, Lai, W., Wang, Y., Wang, Y., Dai, P., Ma, C., Chen, S., Li, Y., Jiang, G., Liang, Z., Ma, W., Gao, Z., Tong, W.M., and Wang, H., 2022 Differential transcriptomic landscapes of multiple organs from SARS-CoV-2 early infected rhesus macaques., Gao, C.C.#, Li, M.#, Deng, W.#, Ma, C.H., Chen, Y.S., Sun, Y.Q., Du, T., Liu, Q.L., Li, W.J., Zhang, B., Sun, L., Liu, S.M., Li, F., Qi, F., Qu, Y., Ge, X., Liu, J., Wang, P., Niu, Y., Liang, Z., Zhao, Y.L., Huang, B., Peng, X.Z., Yang, Y., Qin, C., Tong, W.M., and Yang, Y.G., 2022 ALKBH5 in mouse testicular Sertoli cells regulates Cdh2 mRNA translation to maintain blood-testis barrier integrity., Cai, Z., Zhang, Y., Yang, L., Ma, C., Fei, Y., Ding, J., Song, W., Tong, W.M., Niu, Y., and Li, H., 2022 Genome-wide 5-Hydroxymethylcytosine Profiling Analysis Identifies MAP7D1 as A Novel Regulator of Lymph Node Metastasis in Breast Cancer., Wu, S.L.#, Zhang, X.#, Chang, M., Huang, C., Qian, J., Li, Q., Yuan, F., Sun, L., Yu, X., Cui, X., Jiang, J., Cui, M., Liu, Y., Wu, H.W., Liang, Z.Y., Wang, X., Niu, Y., Tong, W.M., and Jin, F., 2021 RNA N6-methyladenosine modification, spermatogenesis, and human male infertility., Cai, Z., Niu, Y., and Li, H., 2021 RNA m(6)A Methylation Regulators Subclassify Luminal Subtype in Breast Cancer., Yang, L., Wu, S., Ma, C., Song, S., Jin, F., Niu, Y., and Tong, W.M., 2020 RNA m(6)A methylation participates in regulation of postnatal development of the mouse cerebellum., Ma, C.#, Chang, M.#, Lv, H.#, Zhang, Z.W., Zhang, W., He, X., Wu, G., Zhao, S., Zhang, Y., Wang, D., Teng, X., Liu, C., Li, Q., Klungland, A., Niu, Y., Song, S., and Tong, W.M., 2018 Region-specific RNA m(6)A methylation represents a new layer of control in the gene regulatory network in the mouse brain., Chang, M.#, Lv, H.#, Zhang, W., Ma, C., He, X., Zhao, S., Zhang, Z.W., Zeng, Y.X., Song, S., Niu, Y., and Tong, W.M., 2017 Long noncoding RNA MIR31HG exhibits oncogenic property in pancreatic ductal adenocarcinoma and is negatively regulated by miR-193b., Yang, H., Liu, P., Zhang, J., Peng, X., Lu, Z., Yu, S., Meng, Y., Tong, W.M., and Chen, J., 2016 ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility., Zheng, G.#, Dahl, J.A.#, Niu, Y.#, Fedorcsak, P., Huang, C.M., Li, C.J., Vågbø, C.B., Shi, Y., Wang, W.L., Song, S.H., Lu, Z., Bosmans, R.P., Dai, Q., Hao, Y.J., Yang, X., Zhao, W.M., Tong, W.M., Wang, X.J., Bogdan, F., Furu, K., Fu, Y., Jia, G., Zhao, X., Liu, J., Krokan, H.E., Klungland, A., Yang, Y.G., and He, C., 2013 N6-methyl-adenosine (m6A) in RNA: an old modification with a novel epigenetic function., Niu, Y., Zhao, X., Wu, Y.S., Li, M.M., Wang, X.J., and Yang, Y.G., 2013 A distinct response to endogenous DNA damage in the development of Nbs1-deficient cortical neurons., Li, R., Yang, Y.G., Gao, Y., Wang, Z.Q., and Tong, W.M., 2012 Neuronal regeneration and protection by collagen-binding BDNF in the rat middle cerebral artery occlusion model., Guan, J.#, Tong, W.M.#, Ding, W.#, Du, S., Xiao, Z., Han, Q., Zhu, Z., Bao, X., Shi, X., Wu, C., Cao, J., Yang, Y., Ma, W., Li, G., Yao, Y., Gao, J., Wei, J., Dai, J., and Wang, R., 2012

Areas of Focus

Epitranscriptomic RNA m6A methylation in major diseases
Role of protein phosphatases in neurodevelopment and neurodegenerative diseases

Publications

Mic60 is essential to maintain mitochondrial integrity and to prevent encephalomyopathy., Dong, T., Zhang, Z.Q., Sun, L.H., Zhang, W., Zhu, Z., Lin, L., Yang, L., Lv, A., Liu, C., Li, Q., Yang, R.F., Zhang, X., Niu, Y., Chen, H.Z., Liu, D.P.*, and Tong, W.M.*, 2023
METTL3 regulates m(6)A methylation of PTCH1 and GLI2 in Sonic hedgehog signaling to promote tumor progression in SHH-medulloblastoma., Zhang, Z.W.#, Teng, X.#, Zhao, F.#, Ma, C.#, Zhang, J., Xiao, L.F., Wang, Y., Chang, M., Tian, Y., Li, C., Zhang, Z., Song, S*., Tong, W.M. *, Liu, P*., and Niu, Y.*, 2022
Airway administration of bisphosphate and dexamethasone inhibits SARS-CoV-2 variant infection by targeting alveolar macrophages., Wang, Z.#, Zhou, Y.#, Bao, L., Li, D., Lv, J., Wang, D., Li, S., Liu, J., Qin, C.*, Tong, W.M.*, and Huang, B.*, 2022
Rare and misincorporated DNA N(6)-methyladenine is a hallmark of cytotoxic stresses for selectively stimulating the stemness and proliferation of glioblastoma cells., Lyu, C.#, Niu, Y.#, Lai, W., Wang, Y., Wang, Y., Dai, P., Ma, C., Chen, S., Li, Y., Jiang, G., Liang, Z., Ma, W., Gao, Z.*, Tong, W.M.*, and Wang, H.*, 2022
Differential transcriptomic landscapes of multiple organs from SARS-CoV-2 early infected rhesus macaques., Gao, C.C.#, Li, M.#, Deng, W.#, Ma, C.H., Chen, Y.S., Sun, Y.Q., Du, T., Liu, Q.L., Li, W.J., Zhang, B., Sun, L., Liu, S.M., Li, F., Qi, F., Qu, Y., Ge, X., Liu, J., Wang, P., Niu, Y., Liang, Z., Zhao, Y.L., Huang, B., Peng, X.Z., Yang, Y.*, Qin, C.*, Tong, W.M.*, and Yang, Y.G.*, 2022
ALKBH5 in mouse testicular Sertoli cells regulates Cdh2 mRNA translation to maintain blood-testis barrier integrity., Cai, Z., Zhang, Y., Yang, L., Ma, C., Fei, Y., Ding, J., Song, W., Tong, W.M.*, Niu, Y.*, and Li, H.*, 2022
Genome-wide 5-Hydroxymethylcytosine Profiling Analysis Identifies MAP7D1 as A Novel Regulator of Lymph Node Metastasis in Breast Cancer., Wu, S.L.#, Zhang, X.#, Chang, M., Huang, C., Qian, J., Li, Q., Yuan, F., Sun, L., Yu, X., Cui, X., Jiang, J., Cui, M., Liu, Y., Wu, H.W., Liang, Z.Y., Wang, X., Niu, Y.*, Tong, W.M.*, and Jin, F.*, 2021
RNA N6-methyladenosine modification, spermatogenesis, and human male infertility., Cai, Z., Niu, Y.*, and Li, H.*, 2021
RNA m(6)A Methylation Regulators Subclassify Luminal Subtype in Breast Cancer., Yang, L., Wu, S., Ma, C., Song, S., Jin, F., Niu, Y.*, and Tong, W.M.*, 2020
RNA m(6)A methylation participates in regulation of postnatal development of the mouse cerebellum., Ma, C.#, Chang, M.#, Lv, H.#, Zhang, Z.W., Zhang, W., He, X., Wu, G., Zhao, S., Zhang, Y., Wang, D., Teng, X., Liu, C., Li, Q., Klungland, A., Niu, Y.*, Song, S.*, and Tong, W.M.*, 2018
Region-specific RNA m(6)A methylation represents a new layer of control in the gene regulatory network in the mouse brain., Chang, M.#, Lv, H.#, Zhang, W., Ma, C., He, X., Zhao, S., Zhang, Z.W., Zeng, Y.X., Song, S., Niu, Y.*, and Tong, W.M.*, 2017
Long noncoding RNA MIR31HG exhibits oncogenic property in pancreatic ductal adenocarcinoma and is negatively regulated by miR-193b., Yang, H., Liu, P., Zhang, J., Peng, X., Lu, Z., Yu, S., Meng, Y., Tong, W.M.*, and Chen, J.*, 2016
ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility., Zheng, G.#, Dahl, J.A.#, Niu, Y.#, Fedorcsak, P., Huang, C.M., Li, C.J., Vågbø, C.B., Shi, Y., Wang, W.L., Song, S.H., Lu, Z., Bosmans, R.P., Dai, Q., Hao, Y.J., Yang, X., Zhao, W.M., Tong, W.M., Wang, X.J., Bogdan, F., Furu, K., Fu, Y., Jia, G., Zhao, X., Liu, J., Krokan, H.E., Klungland, A.*, Yang, Y.G.*, and He, C.*, 2013
N6-methyl-adenosine (m6A) in RNA: an old modification with a novel epigenetic function., Niu, Y., Zhao, X., Wu, Y.S., Li, M.M., Wang, X.J., and Yang, Y.G.*, 2013
A distinct response to endogenous DNA damage in the development of Nbs1-deficient cortical neurons., Li, R., Yang, Y.G., Gao, Y., Wang, Z.Q., and Tong, W.M.*, 2012
Neuronal regeneration and protection by collagen-binding BDNF in the rat middle cerebral artery occlusion model., Guan, J.#, Tong, W.M.#, Ding, W.#, Du, S., Xiao, Z., Han, Q., Zhu, Z., Bao, X., Shi, X., Wu, C., Cao, J., Yang, Y., Ma, W., Li, G., Yao, Y., Gao, J., Wei, J., Dai, J.*, and Wang, R.*, 2012

Epitranscriptomics Rna M6A Methylation Cancer Neurodegeneration Protein Phosphatases Neurodevelopment Disease Models Gene Engineering

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