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佟伟民
010-69156945\nwmtong(AT)ibms.pumc.edu.cn
中文, 英文
北京
北京协和医学院
Medical Laboratory Animal Research Institute
  • 1994-1996 理学博士:维也纳大学
  • 1988-1991 病理学硕士:白求恩医科大学
  • 1981-1986 法医学学士:中国医科大学
  • 2007年至今 - 中国医学科学院基础医学研究所暨北京协和医学院基础学院 - 教授
  • 2000-2007 - 世界卫生组织国际癌症研究署 - 研究员
  • 1997-2000 - 世界卫生组织国际癌症研究署 - 博士后
表观转录标记RNA m6A甲基化在重大疾病中的功能与机制
蛋白磷酸酶在神经发育与神经退行性病变中的作用与机制
  • Mic60 is essential to maintain mitochondrial integrity and to prevent encephalomyopathy., Dong, T., Zhang, Z.Q., Sun, L.H., Zhang, W., Zhu, Z., Lin, L., Yang, L., Lv, A., Liu, C., Li, Q., Yang, R.F., Zhang, X., Niu, Y., Chen, H.Z., Liu, D.P.*, and Tong, W.M.*, 2023
  • METTL3 regulates m(6)A methylation of PTCH1 and GLI2 in Sonic hedgehog signaling to promote tumor progression in SHH-medulloblastoma., Zhang, Z.W.#, Teng, X.#, Zhao, F.#, Ma, C.#, Zhang, J., Xiao, L.F., Wang, Y., Chang, M., Tian, Y., Li, C., Zhang, Z., Song, S*., Tong, W.M. *, Liu, P*., and Niu, Y.*, 2022
  • Airway administration of bisphosphate and dexamethasone inhibits SARS-CoV-2 variant infection by targeting alveolar macrophages., Wang, Z.#, Zhou, Y.#, Bao, L., Li, D., Lv, J., Wang, D., Li, S., Liu, J., Qin, C.*, Tong, W.M.*, and Huang, B.*, 2022
  • Rare and misincorporated DNA N(6)-methyladenine is a hallmark of cytotoxic stresses for selectively stimulating the stemness and proliferation of glioblastoma cells., Lyu, C.#, Niu, Y.#, Lai, W., Wang, Y., Wang, Y., Dai, P., Ma, C., Chen, S., Li, Y., Jiang, G., Liang, Z., Ma, W., Gao, Z.*, Tong, W.M.*, and Wang, H.*, 2022
  • Differential transcriptomic landscapes of multiple organs from SARS-CoV-2 early infected rhesus macaques., Gao, C.C.#, Li, M.#, Deng, W.#, Ma, C.H., Chen, Y.S., Sun, Y.Q., Du, T., Liu, Q.L., Li, W.J., Zhang, B., Sun, L., Liu, S.M., Li, F., Qi, F., Qu, Y., Ge, X., Liu, J., Wang, P., Niu, Y., Liang, Z., Zhao, Y.L., Huang, B., Peng, X.Z., Yang, Y.*, Qin, C.*, Tong, W.M.*, and Yang, Y.G.*, 2022
  • ALKBH5 in mouse testicular Sertoli cells regulates Cdh2 mRNA translation to maintain blood-testis barrier integrity., Cai, Z., Zhang, Y., Yang, L., Ma, C., Fei, Y., Ding, J., Song, W., Tong, W.M.*, Niu, Y.*, and Li, H.*, 2022
  • Genome-wide 5-Hydroxymethylcytosine Profiling Analysis Identifies MAP7D1 as A Novel Regulator of Lymph Node Metastasis in Breast Cancer., Wu, S.L.#, Zhang, X.#, Chang, M., Huang, C., Qian, J., Li, Q., Yuan, F., Sun, L., Yu, X., Cui, X., Jiang, J., Cui, M., Liu, Y., Wu, H.W., Liang, Z.Y., Wang, X., Niu, Y.*, Tong, W.M.*, and Jin, F.*, 2021
  • RNA N6-methyladenosine modification, spermatogenesis, and human male infertility., Cai, Z., Niu, Y.*, and Li, H.*, 2021
  • RNA m(6)A Methylation Regulators Subclassify Luminal Subtype in Breast Cancer., Yang, L., Wu, S., Ma, C., Song, S., Jin, F., Niu, Y.*, and Tong, W.M.*, 2020
  • RNA m(6)A methylation participates in regulation of postnatal development of the mouse cerebellum., Ma, C.#, Chang, M.#, Lv, H.#, Zhang, Z.W., Zhang, W., He, X., Wu, G., Zhao, S., Zhang, Y., Wang, D., Teng, X., Liu, C., Li, Q., Klungland, A., Niu, Y.*, Song, S.*, and Tong, W.M.*, 2018
  • Region-specific RNA m(6)A methylation represents a new layer of control in the gene regulatory network in the mouse brain., Chang, M.#, Lv, H.#, Zhang, W., Ma, C., He, X., Zhao, S., Zhang, Z.W., Zeng, Y.X., Song, S., Niu, Y.*, and Tong, W.M.*, 2017
  • Long noncoding RNA MIR31HG exhibits oncogenic property in pancreatic ductal adenocarcinoma and is negatively regulated by miR-193b., Yang, H., Liu, P., Zhang, J., Peng, X., Lu, Z., Yu, S., Meng, Y., Tong, W.M.*, and Chen, J.*, 2016
  • ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility., Zheng, G.#, Dahl, J.A.#, Niu, Y.#, Fedorcsak, P., Huang, C.M., Li, C.J., Vågbø, C.B., Shi, Y., Wang, W.L., Song, S.H., Lu, Z., Bosmans, R.P., Dai, Q., Hao, Y.J., Yang, X., Zhao, W.M., Tong, W.M., Wang, X.J., Bogdan, F., Furu, K., Fu, Y., Jia, G., Zhao, X., Liu, J., Krokan, H.E., Klungland, A.*, Yang, Y.G.*, and He, C.*, 2013
  • N6-methyl-adenosine (m6A) in RNA: an old modification with a novel epigenetic function., Niu, Y., Zhao, X., Wu, Y.S., Li, M.M., Wang, X.J., and Yang, Y.G.*, 2013
  • A distinct response to endogenous DNA damage in the development of Nbs1-deficient cortical neurons., Li, R., Yang, Y.G., Gao, Y., Wang, Z.Q., and Tong, W.M.*, 2012
  • Neuronal regeneration and protection by collagen-binding BDNF in the rat middle cerebral artery occlusion model., Guan, J.#, Tong, W.M.#, Ding, W.#, Du, S., Xiao, Z., Han, Q., Zhu, Z., Bao, X., Shi, X., Wu, C., Cao, J., Yang, Y., Ma, W., Li, G., Yao, Y., Gao, J., Wei, J., Dai, J.*, and Wang, R.*, 2012
表观转录组学 Rna M6A 甲基化 癌症 神经退行性 蛋白磷酸酶 神经发育 疾病模型 基因工程

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