Professor | Jingchun Guo | Asia Growth Partners

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Name

Jingchun Guo

Contact Information

jingchunguo@shmu.edu.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Fudan University
Faculty	Brain Science Research Institute
Academic Background & Achievements	2005 - PhD: Fudan University Achievement: Conducted significant research in neurobiology, focusing on molecular mechanisms of neurodegeneration and neuroprotection.

University/Lab Affiliation and Title

Fudan University

Faculty

Brain Science Research Institute

Academic Background & Achievements

2005 - PhD: Fudan University
Achievement: Conducted significant research in neurobiology, focusing on molecular mechanisms of neurodegeneration and neuroprotection.

Areas of Focus	Molecular mechanisms of metabolism-related neurodegeneration and neuroprotection
Publications	High glucose and palmitic acid induces neuronal senescence by NRSF/REST elevation and the subsequent mTOR-related autophagy suppression., Xue WJ, He CF, Zhou RY, Xu XD, Xiang LX, Wang JT, Wang XR, Zhou HG, Guo JC, 2022 Knockdown of NRSF Alleviates Ischemic Brain Injury and Microvasculature Defects in Diabetic MCAO Mice., He CF, Xue WJ, Xu XD, Wang JT, Wang XR, Feng Y, Zhou HG, Guo JC, 2022 9-PAHSA Improves Cardiovascular Complications by Promoting Autophagic Flux and Reducing Myocardial Hypertrophy in Db/Db Mice., Wang YM, Mi SL, Jin H, Guo QL, Yu ZY, Wang JT, Zhang XM, Zhang Q, Wang NN, Huang YY, Zhou HG, Guo JC, 2021 A novel palmitic acid hydroxy stearic acid (5-PAHSA) plays a neuroprotective role by inhibiting phosphorylation of the m-TOR-ULK1 pathway and regulating autophagy., Wang JT, Yu ZY, Tao YH, Liu YC, Wang YM, Guo QL, Xue JZ, Wen XH, Zhang Q, Xu XD, He CF, Xue WJ, Guo JC, Zhou HG, 2021 Increased NRSF/REST in anterior cingulate cortex contributes to diabetes-related neuropathic pain., Xu XD, Wen XH, He CF, Yu ZY, Wang JT, Zhou HG, Guo JC, 2020

Areas of Focus

Molecular mechanisms of metabolism-related neurodegeneration and neuroprotection

Publications

High glucose and palmitic acid induces neuronal senescence by NRSF/REST elevation and the subsequent mTOR-related autophagy suppression., Xue WJ, He CF, Zhou RY, Xu XD, Xiang LX, Wang JT, Wang XR, Zhou HG, Guo JC, 2022
Knockdown of NRSF Alleviates Ischemic Brain Injury and Microvasculature Defects in Diabetic MCAO Mice., He CF, Xue WJ, Xu XD, Wang JT, Wang XR, Feng Y, Zhou HG, Guo JC, 2022
9-PAHSA Improves Cardiovascular Complications by Promoting Autophagic Flux and Reducing Myocardial Hypertrophy in Db/Db Mice., Wang YM, Mi SL, Jin H, Guo QL, Yu ZY, Wang JT, Zhang XM, Zhang Q, Wang NN, Huang YY, Zhou HG, Guo JC, 2021
A novel palmitic acid hydroxy stearic acid (5-PAHSA) plays a neuroprotective role by inhibiting phosphorylation of the m-TOR-ULK1 pathway and regulating autophagy., Wang JT, Yu ZY, Tao YH, Liu YC, Wang YM, Guo QL, Xue JZ, Wen XH, Zhang Q, Xu XD, He CF, Xue WJ, Guo JC, Zhou HG, 2021
Increased NRSF/REST in anterior cingulate cortex contributes to diabetes-related neuropathic pain., Xu XD, Wen XH, He CF, Yu ZY, Wang JT, Zhou HG, Guo JC, 2020

Neurodegeneration Neuroprotection Metabolism Molecular Mechanisms Neurobiology Diabetes Brain Aging Nrsf/Rest Autophagy Lipid Metabolism

Miao Yanying - Fudan University

Gang Peng - Fudan University

Tang Yiquan - Fudan University

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