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Qiang Liu
Life Science
University of Science and Technology of China
Anhui
Language: English, Chinese
Brain Aging
Alzheimer'S Disease
Molecular Mechanisms
Cellular Mechanisms
Lipid Metabolism
Neurodegenerative Diseases
Epigenetic Regulation
Learning
Memory
Research
Areas of Focus
- Molecular and cellular mechanisms of brain aging and Alzheimer's disease
- Role of brain lipid metabolism in neurodegenerative diseases and aging
- Epigenetic regulation mechanisms in learning and memory
Work Experience
- Postdoctoral Research - Washington University School of Medicine
- Postdoctoral Research - University of Pennsylvania School of Medicine
- Deputy Director - Key Laboratory of Brain Function and Brain Diseases, CAS
- Deputy Director - Key Laboratory of Aging Biomedical, Anhui Province
Academic Background & Achievements
- 2005 - PhD: Institute of Biophysics, Chinese Academy of Sciences
- National Outstanding Youth Science Fund Recipient (2021)
- National Innovative Talent Program (2012)
- National Excellent Youth Science Fund Recipient (2014)
- Core Member of CAS Center for Excellence in Brain Science and Intelligence Technology (2019)
Publications
- Aging-induced tRNAGlu-derived fragment impairs glutamate biosynthesis by targeting mitochondrial translation-dependent cristae organization., Li D, Gao X, Ma X, Wang M, Cheng C, Xue T, Gao F, Shen Y, Zhang J, Liu Q., 2024
- Nucleolus assembly impairment leads to two-cell transcriptional repression via NPM1-mediated PRC2 recruitment., Li D, Cao R, Li Q, Yang Y, Tang A, Zhang J, Liu Q., 2023
- Astrocytic ApoE reprograms neuronal cholesterol metabolism and histone acetylation-mediated memory., Li XH, Zhang J, Li DF, He C, He K, Xue T, Wan L, Zhang C and Liu Q., 2021
- Brain cell type-specific cholesterol metabolism and implications for learning and memory., Li D, Zhang J, Liu Q., 2022
- Activity dependent LoNA Regulates Translation by Coordinating rRNA Transcription and Methylation., Li D, Zhang J, Wang M, Li X, Gong H, Tang H, Chen L, Wan L and Liu Q., 2018
- SFRS11 loss leads to aging-associated cognitive decline by modulating LRP8 and ApoE., Raihan O, Brishti A, Li Q, Zhang Q, Li D, Li X, Zhang Q, Xie Z, Li J, Zhang J, Liu Q., 2019
- Nuclear speckle specific hnRNP D-like prevents age- and AD-related cognitive decline by modulating RNA splicing., Zhang Q, Zhang J, Ye J, Li X, Liu H, Ma X, Wang C, He K, Zhang W, Yuan J, Zhao Y, Xu H, Liu Q., 2021
- Age- and disease-related memory decline: epigenetic biomarker and treatment., Zhang J, Liu Q., 2023
- Aging-induced YTHDF aggregates impair mitochondrial function by trapping mitochondrial RNAs and suppressing their expression in the brain., Zhang J, Li D, He K, Liu Q*, Xie Z*., 2024
- Mechanistic insights on non-coding RNAs in learning and memory., Li D, Zhang J, Liu Q., 2023
- Cholesterol metabolism and homeostasis in the brain., Zhang J, Liu Q., 2015
Awards
- National Outstanding Youth Science Fund Recipient (2021)
- National Innovative Talent Program (2012)
- National Excellent Youth Science Fund Recipient (2014)
