Professor | 刘强 | 数字化转型顾问

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Name	刘强
Contact Information	liuq2012@ustc.edu.cn
Language ability	英语, 中文
Province	安徽

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Name

刘强

Contact Information

liuq2012@ustc.edu.cn

Language ability

英语, 中文

Province

安徽

University/Lab Affiliation and Title	中国科学技术大学
Faculty	Life Sciences
Academic Background & Achievements	2005 - 博士: 中国科学院生物物理研究所国家杰出青年科学基金获得者（2021）国家创新人才计划（2012）国家优秀青年科学基金获得者（2014）中科院动物进化与遗传前沿交叉卓越创新中心骨干（2019）
Work Experience	博士后研究 - 华盛顿大学医学院博士后研究 - 宾夕法尼亚大学医学院副主任 - 中科院脑功能与脑疾病重点实验室副主任 - 衰老生物医学安徽省重点实验室
Awards	国家杰出青年科学基金获得者（2021）国家创新人才计划（2012）国家优秀青年科学基金获得者（2014）

University/Lab Affiliation and Title

中国科学技术大学

Faculty

Life Sciences

Academic Background & Achievements

2005 - 博士: 中国科学院生物物理研究所
国家杰出青年科学基金获得者（2021）
国家创新人才计划（2012）
国家优秀青年科学基金获得者（2014）
中科院动物进化与遗传前沿交叉卓越创新中心骨干（2019）

Work Experience

博士后研究 - 华盛顿大学医学院
博士后研究 - 宾夕法尼亚大学医学院
副主任 - 中科院脑功能与脑疾病重点实验室
副主任 - 衰老生物医学安徽省重点实验室

Awards

国家杰出青年科学基金获得者（2021）
国家创新人才计划（2012）
国家优秀青年科学基金获得者（2014）

Areas of Focus	脑衰老和阿尔茨海默病的分子细胞机制探索大脑脂代谢在神经退行性疾病以及衰老过程中的作用机制研究表观遗传调控在学习记忆中的作用机制解析
Publications	Aging-induced tRNAGlu-derived fragment impairs glutamate biosynthesis by targeting mitochondrial translation-dependent cristae organization., Li D, Gao X, Ma X, Wang M, Cheng C, Xue T, Gao F, Shen Y, Zhang J, Liu Q., 2024 Nucleolus assembly impairment leads to two-cell transcriptional repression via NPM1-mediated PRC2 recruitment., Li D, Cao R, Li Q, Yang Y, Tang A, Zhang J, Liu Q., 2023 Astrocytic ApoE reprograms neuronal cholesterol metabolism and histone acetylation-mediated memory., Li XH, Zhang J, Li DF, He C, He K, Xue T, Wan L, Zhang C and Liu Q., 2021 Brain cell type-specific cholesterol metabolism and implications for learning and memory., Li D, Zhang J, Liu Q., 2022 Activity dependent LoNA Regulates Translation by Coordinating rRNA Transcription and Methylation., Li D, Zhang J, Wang M, Li X, Gong H, Tang H, Chen L, Wan L and Liu Q., 2018 SFRS11 loss leads to aging-associated cognitive decline by modulating LRP8 and ApoE., Raihan O, Brishti A, Li Q, Zhang Q, Li D, Li X, Zhang Q, Xie Z, Li J, Zhang J, Liu Q., 2019 Nuclear speckle specific hnRNP D-like prevents age- and AD-related cognitive decline by modulating RNA splicing., Zhang Q, Zhang J, Ye J, Li X, Liu H, Ma X, Wang C, He K, Zhang W, Yuan J, Zhao Y, Xu H, Liu Q., 2021 Age- and disease-related memory decline: epigenetic biomarker and treatment., Zhang J, Liu Q., 2023 Aging-induced YTHDF aggregates impair mitochondrial function by trapping mitochondrial RNAs and suppressing their expression in the brain., Zhang J, Li D, He K, Liu Q, Xie Z., 2024 Mechanistic insights on non-coding RNAs in learning and memory., Li D, Zhang J, Liu Q., 2023 Cholesterol metabolism and homeostasis in the brain., Zhang J, Liu Q., 2015

Areas of Focus

脑衰老和阿尔茨海默病的分子细胞机制探索
大脑脂代谢在神经退行性疾病以及衰老过程中的作用机制研究
表观遗传调控在学习记忆中的作用机制解析

Publications

Aging-induced tRNAGlu-derived fragment impairs glutamate biosynthesis by targeting mitochondrial translation-dependent cristae organization., Li D, Gao X, Ma X, Wang M, Cheng C, Xue T, Gao F, Shen Y, Zhang J, Liu Q., 2024
Nucleolus assembly impairment leads to two-cell transcriptional repression via NPM1-mediated PRC2 recruitment., Li D, Cao R, Li Q, Yang Y, Tang A, Zhang J, Liu Q., 2023
Astrocytic ApoE reprograms neuronal cholesterol metabolism and histone acetylation-mediated memory., Li XH, Zhang J, Li DF, He C, He K, Xue T, Wan L, Zhang C and Liu Q., 2021
Brain cell type-specific cholesterol metabolism and implications for learning and memory., Li D, Zhang J, Liu Q., 2022
Activity dependent LoNA Regulates Translation by Coordinating rRNA Transcription and Methylation., Li D, Zhang J, Wang M, Li X, Gong H, Tang H, Chen L, Wan L and Liu Q., 2018
SFRS11 loss leads to aging-associated cognitive decline by modulating LRP8 and ApoE., Raihan O, Brishti A, Li Q, Zhang Q, Li D, Li X, Zhang Q, Xie Z, Li J, Zhang J, Liu Q., 2019
Nuclear speckle specific hnRNP D-like prevents age- and AD-related cognitive decline by modulating RNA splicing., Zhang Q, Zhang J, Ye J, Li X, Liu H, Ma X, Wang C, He K, Zhang W, Yuan J, Zhao Y, Xu H, Liu Q., 2021
Age- and disease-related memory decline: epigenetic biomarker and treatment., Zhang J, Liu Q., 2023
Aging-induced YTHDF aggregates impair mitochondrial function by trapping mitochondrial RNAs and suppressing their expression in the brain., Zhang J, Li D, He K, Liu Q*, Xie Z*., 2024
Mechanistic insights on non-coding RNAs in learning and memory., Li D, Zhang J, Liu Q., 2023
Cholesterol metabolism and homeostasis in the brain., Zhang J, Liu Q., 2015

脑衰老阿尔茨海默病分子机制细胞机制脂代谢神经退行性疾病表观遗传调控学习记忆研究

孙方霖 - 同济大学

Area of Focus
表观遗传学 | 分子机制 | 调控 | 异染色质 | 结构 | 功能 | 干细胞 | 衰老 | 网络 | 研究

李丹 - 上海交通大学

平勇 - 上海交通大学

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