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Tao Yuyong
Life Science
University of Science and Technology of China
Anhui
Language: English, Chinese
Membrane Proteins
Structural Biology
Signal Transduction
Antibody Design
Protein Engineering
Synthetic Biology
Cell Signaling
Transmembrane Transport
Molecular Mechanisms
Therapeutic Development
Areas of Focus
- Membrane Protein Structure and Function Research
- Antibody Design and Protein Engineering
- Synthetic Biology
Work Experience
- 2013-2016 - Stanford University School of Medicine, Department of Molecular and Cellular Physiology - Postdoctoral Research
- 2016-2017 - University of Toronto, Donnelly Centre - Postdoctoral Research
Academic Background & Achievements
- 2012 - PhD: University of Science and Technology of China
- Selected for the National Overseas High-Level Talent Youth Program
Publications
- A method for structure determination of GPCRs in various states, Guo Q, He B, Zhong Y, Jiao H, Ren Y, Wang Q, Ge Q, Gao Y, Liu X, Du Y, Hu H, Tao Y., 2023
- Engineering a modular double-transmembrane synthetic receptor system for customizing cellular programs, Zhou J, Ge Q, Wang D, Guo Q, Tao Y., 2023
- An epitope-directed selection strategy facilitating the identification of Frizzled receptor selective antibodies, Ge Q, Teng M, Li X, Guo Q, Tao Y., 2023
- Structural basis of the ligand binding and signaling mechanism of melatonin receptors, Wang Q, Lu Q, Guo Q, Teng M, Gong Q, Li X, Du Y, Liu Z, Tao Y., 2022
- Interface switch mediates signal transmission in a two-component system, Wang M, Guo Q, Zhu K, Fang B, Yang Y, Teng M, Li X, Tao Y., 2020
- A potent synthetic nanobody with broad-spectrum activity neutralizes SARS-CoV-2 virus and the Omicron variant BA.1 through a unique binding mode, Zhao D, Liu L, Liu X, Zhang J, Yin Y, Luan L, Jiang D, Yang X, Li L, Xiong H, Xing D, Zheng Q, Xia N, Tao Y, Li S, Huang H., 2022
- Structure of a eukaryotic SWEET transporter in a homo-trimeric complex, Tao Y, Cheung L, Li S, Eom J, Chen L, Xu Y, Perry K, Frommer W, Feng L., 2015
- Tailored tetravalent antibodies potently and specifically activate Wnt/Frizzled pathways in cells, organoids and mice, Tao Y, Mis M, Blazer L, Ustav M Jnr, Steinhart Z, Chidiac R, Kubarakos E, O'Brien S, Wang X, Jarvik N, Patel N, Adams J, Moffat J, Angers S, Sidhu SS., 2019
- Structures of bacterial homologues of SWEET transporters in two distinct conformations, Xu Y, Tao Y, Cheung L, Fan C, Chen L, Xu S, Perry K, Frommer W, Feng L., 2014
Awards
- Selected for the National Overseas High-Level Talent Youth Program
