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Wenchao Zhou
wzaz@ustc.edu.cn
English, Chinese
Anhui
University of Science and Technology of China
Life Sciences
  • 1997-2001: Bachelor of Science in Biochemistry, Zhejiang University
  • 2001-2009: Doctor of Science in Biochemistry and Molecular Biology, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences
  • Published over 20 papers in journals like Cell, Cell Stem Cell, Nature Cell Biology, Science Translational Medicine
  • Total citations exceed 3000
  • 2009-2011: Postdoctoral Researcher, Ohio State University Medical Center, USA
  • 2011-2018: Postdoctoral Researcher, Cleveland Medical Center, USA
  • 2018-present: Special Researcher, School of Life Sciences and First Affiliated Hospital, University of Science and Technology of China
Glioma stem cells and tumor-associated macrophage interaction molecular mechanisms
Molecular regulation mechanisms of differentiation and maintenance of glioma tumor perivascular cells
Signaling pathways related to the maintenance of glioma stem cell stemness
  • Stabilization of Pin1 by USP34 promotes Ubc9 isomerization and protein sumoylation in glioma stem cells., Qiuhong Zhu, Panpan Liang, Hao Meng, Fangzhen Li, Wei Miao, Cuiying Chu, Wei Wang, Dongxue Li, Cong Chen, Yu Shi, Xingjiang Yu, Yifang Ping, Chaoshi Niu, Hai-Bo Wu, Aili Zhang, Xiu-Wu Bian, Wenchao Zhou, 2024
  • USP33 deubiquitinates and stabilizes HIF‐2alpha to promote hypoxia response in glioma stem cells., Aili Zhang, Zhi Huang, Weiwei Tao, Kui Zhai, Qiulian Wu, Jeremy N Rich, Wenchao Zhou, Shideng Bao, 2022
  • Protein sumoylation with SUMO1 promoted by Pin1 in glioma stem cells augments glioblastoma malignancy., Aili Zhang, Weiwei Tao, Kui Zhai, Xiaoguang Fang, Zhi Huang, Jennifer S Yu, Andrew E Sloan, Jeremy N Rich, Wenchao Zhou, Shideng Bao, 2020
  • Low level of tumor necrosis factor α in tumor microenvironment maintains self-renewal of glioma stem cells by Vasorin-mediated glycolysis., Yang Zhang, Tianxu Kang, Yuxi Wang, Chao Song, Huan Li, Hailong Mi, Yachao Li, Minhai Dong, Xiaoyu Ma, Hongtao Zhu, Lidong Cheng, Po Zhang, Zhiye Chen, Lin Zhou, Qiulian Wu, Feng Mao, Baofeng Wang, Suojun Zhang, Kai Shu, Feng Wan, Wenchao Zhou, Jeremy N Rich, Jianying Shen, Qungen Xiao, Xingjiang Yu, 2024
  • Phosphocreatine promotes epigenetic reprogramming to facilitate glioblastoma growth through stabilizing BRD2., Lishu Chen, Qinghui Qi, Xiaoqing Jiang, Jin Wu, Yuanyuan Li, Zhaodan Liu, Yan Cai, Haowen Ran, Songyang Zhang, Cheng Zhang, Huiran Wu, Shuailiang Cao, Lanjuan Mi, Dake Xiao, Haohao Huang, Shuai Jiang, Jiaqi Wu, Bohan Li, Jiong Xie, Ji Qi, Fangye Li, Panpan Liang, Qiuying Han, Min Wu, Wenchao Zhou, Chenhui Wang, Weina Zhang, Xin Jiang, Kun Zhang, Huiyan Li, Xuemin Zhang, Ailing Li, Tao Zhou, Jianghong Man, 2024
  • Transgelin Promotes Glioblastoma Stem Cell Hypoxic Responses and Maintenance Through p53 Acetylation., Huan Li, Chao Song, Yang Zhang, Guohao Liu, Hailong Mi, Yachao Li, Zhiye Chen, Xiaoyu Ma, Po Zhang, Lidong Cheng, Peng Peng, Hongtao Zhu, Zirong Chen, Minhai Dong, Sui Chen, Hao Meng, QunGen Xiao, Honglian Li, Qiulian Wu, Baofeng Wang, Suojun Zhang, Kai Shu, Feng Wan, Dongsheng Guo, Wenchao Zhou, Lin Zhou, Feng Mao, Jeremy N Rich, Xingjiang Yu, 2024
  • Voluntary-Opsonization-Enabled Precision Nanomedicines for Inflammation Treatment., Shuya Li, Min Li, Shaohu Huo, Qin Wang, Jing Chen, Shenggang Ding, Zhutian Zeng, Wenchao Zhou, Yucai Wang, Jun Wang, 2021
  • SATB2 drives glioblastoma growth by recruiting CBP to promote FOXM1 expression in glioma stem cells., Weiwei Tao, Aili Zhang, Kui Zhai, Zhi Huang, Haidong Huang, Wenchao Zhou, Qian Huang, Xiaoguang Fang, Briana C Prager, Xiuxing Wang, Qiulian Wu, Andrew E Sloan, Manmeet S Ahluwalia, Justin D Lathia, Jennifer S Yu, Jeremy N Rich, Shideng Bao, 2020
  • Dual Role of WISP1 in maintaining glioma stem cells and tumor-supportive macrophages in glioblastoma., Weiwei Tao, Chengwei Chu, Wenchao Zhou, Zhi Huang, Kui Zhai, Xiaoguang Fang, Qian Huang, Aili Zhang, Xiuxing Wang, Xingjiang Yu, Haidong Huang, Qiulian Wu, Andrew E Sloan, S Yu Jennifer, Xiaoxia Li, George R Stark, Jeremy N Rich, Shideng Bao, 2020
  • Nano Lett., Shuya Li, Qin Wang, Yanqiong Shen, Muhammad Hassan, Jizhou Shen, Wei Jiang, Yitan Su, Jing Chen, Li Bai, Wenchao Zhou, Yucai Wang, 2020
  • Cancer Discov., Zhen Dong, Guoxin Zhang, Meng Qu, Ryan C Gimple, Qiulian Wu, Zhixin Qiu, Briana C Prager, Xiuxing Wang, Leo JY Kim, Andrew R Morton, Deobrat Dixit, Wenchao Zhou, Haidong Huang, Bin Li, Zhe Zhu, Shideng Bao, Stephen C Mack, Lukas Chavez, Steve A Kay, Jeremy N Rich, 2019
  • Targeting pyrimidine synthesis accentuates molecular therapy response in glioblastoma stem cells., Xiuxing Wang, Kailin Yang, Qiulian Wu, Leo JY Kim, Andrew R Morton, Ryan C Gimple, Briana C Prager, Yu Shi, Wenchao Zhou, Shruti Bhargava, Zhe Zhu, Li Jiang, Weiwei Tao, Zhixin Qiu, Linjie Zhao, Guoxing Zhang, Xiqing Li, Sameer Agnihotri, Paul S Mischel, Stephen C Mack, Shideng Bao, Jeremy N Rich, 2019
  • Chromatin landscapes reveal developmentally encoded transcriptional states that define human glioblastoma., Stephen C Mack, Irtisha Singh, Xiuxing Wang, Rachel Hirsch, Quilian Wu, Rosie Villagomez, Jean A Bernatchez, Zhe Zhu, Ryan C Gimple, Leo JY Kim, Andrew Morton, Sisi Lai, Zhixin Qiu, Briana C Prager, Kelsey C Bertrand, Clarence Mah, Wenchao Zhou, Christine Lee, Gene H Barnett, Michael A Vogelbaum, Andrew E Sloan, Lukas Chavez, Shideng Bao, Peter C Scacheri, Jair L Siqueira-Neto, Charles Y Lin, Jeremy N Rich, 2019
Glioma Stem Cells Macrophages Tumor Microenvironment Molecular Mechanisms Differentiation Maintenance Signaling Pathways Tumor Progression Therapeutic Targets

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