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Yang Cao
Basic Medical Sciences
University of Science and Technology of China
Anhui
Language: English, Chinese
Cardiovascular
Metabolism
Heart Failure
Genetics
Molecular Biology
Physiology
Organ Interaction
Liver
Microbiota
Mitochondria
Areas of Focus
- Cardiovascular metabolic diseases
- Organ interaction in heart failure
- Genetic mechanisms of cardiac diastolic function
- Liver metabolism and gut microbiota in cardiac function
- Role of mitochondrial function in cardiovascular metabolic diseases
Work Experience
- 2015-2023 - Postdoctoral and Assistant Researcher: University of Washington, Yale University, University of California, Los Angeles
- 2023 April - Present: University of Science and Technology of China, Department of Life Sciences and Medicine
Academic Background & Achievements
- 2015 - PhD: University of Science and Technology of China
- Selected for the National Overseas High-Level Talent Program
Publications
- Liver-heart cross-talk mediated by coagulation factor XI protects against heart failure., Cao Y, Wang Y-C, Zhou Z, Pan C, Jiang L, Zhou Z, Meng Y, Charugundla S, Li T, Allayee H, Seldin MM, and Lusis AJ., 2022
- Identification of DNA Damage Repair Enzyme Ascc2 as Causal for Heart Failure with Preserved Ejection Fraction (HFpEF)., Cao Y, Pan C, Wang Y-C, Zhou Z, Jedian V, Meng Y, Campbell G, Guardino K, Li C, Wang J, and Lusis AJ., 2022
- Indole-3-Propionic Acid Protects Against Heart Failure With Preserved Ejection Fraction., Wang YC, Koay YC, Pan C, Zhou Z, Wilson Tang WH, Wilcox J, Li XS, Zagouras A, Marques F, Allayee H, Rey FE, Kaye DM, O'Sullivan JF, Hazen SL, Cao Y*, and Lusis AJ*., 2024
- Sex Differences in Heart Mitochondria Regulate Diastolic Dysfunction., Cao Y, Vergnes L, Wang Y-C, Pan C, Krishnan KC, Moore TM, Rosa-Garrido M, Kimball TH, Zhou Z, Charugundla S, Rau CD, Seldin MM, Wang J, Vondriska TM, Wang Y, Reue K, and Lusis AJ., 2022
- Activation of γ2-AMPK Suppresses Ribosome Biogenesis and Protects Against Myocardial Ischemia/Reperfusion Injury., Cao Y#, Bojjireddy N#, Kim M, Li T, Zhai P, Nagarajan N, Sadoshima J, Palmiter RD, Tian R., 2017
- miR-290/371-Mbd2-Myc circuit regulates glycolytic metabolism to promote pluripotency., Cao Y#, Guo WT#, Tian S, He X, Wang XW, Liu X, Gu KL, Ma X, Huang D, Hu L, Cai Y, Zhang H, Wang Y, Gao P., 2015
- Coagulation factor with potential for the treatment of heart failure., Cao Y*, Lusis AJ., 2022
- Role of gut microbe-derived metabolites in cardiometabolic diseases: Systems based approach., Cao Y#, Aquino-Martinez R#, Hutchison E#, Allayee H, Lusis AJ*, and Rey FE., 2022
- Heterogeneity of small intestinal immune and epithelial cells and their cellular response network to a western diet., Wang YC, Cao Y, Pan C, Zhou ZQ, Yang LL, Lusis AJ., 2023
- Defective Branched-Chain Amino Acid Catabolism Disrupts Glucose Metabolism and Sensitizes the Heart to Ischemia-Reperfusion Injury., Li T, Zhang Z, Kolwicz SC Jr, Abell L, Roe ND, Kim M, Zhou B, Cao Y, Ritterhoff J, Gu H, Raftery D, Sun H, Tian R., 2017
- Parkin Regulates Adiposity by Coordinating Mitophagy with Mitochondrial Biogenesis in White Adipocytes., Moore T, Cheng L, Wolf D, Ngo J, Segawa M, Zhu X, Strumwasser A, Cao Y, Clifford B, Ma A, Scumpia P, Shirihai O, Vallim T, Laakso M, Lusis AJ, Hevener A, Zhenqi Zhou., 2022
- Failed Power Plant Turns into Mass Murder: New Insight on Mitochondrial Cardiomyopathy., Lee CF, Cao Y, Tian R., 2018
- Genetic Architecture of Heart Mitochondrial Proteome influencing Cardiac Hypertrophy., Krishnan KC, Hachem EJ, Keller MP, Patel SG, Carroll L, Vegas AD, Gyuricza IG, Light C, Cao Y, Pan C, Kaczor-Urbanowicz KE, Shravah V, Anum D, Pellegrini M, Lee CF, Seldin MM, Rosenthal NA, Churchill GA, Attie AD, Parker BL, James DE, and Lusis AJ., 2023
Awards
- Selected for the National Overseas High-Level Talent Program
