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Jian Wang
Basic Medical Sciences
University of Science and Technology of China
Anhui
Language: Chinese, English
T Cells
Antigen Epitopes
Disease Pathogenesis
Tcr
Peptide Vaccines
Mrna Vaccines
Tcr-T
Immune Response
Autoimmunity
Cellular Immunology
Areas of Focus
- Identification of disease-related T cell phenotypes and functions
- Screening of disease-related T cell antigen epitopes and elucidation of T cell-mediated disease pathogenesis
- Disease treatment based on antigen epitopes and T cell receptors (TCR), such as peptide vaccines, mRNA vaccines, and TCR-T
Work Experience
- 2012-2015 - Postdoctoral Research: University of Science and Technology of China
- 2017-2021 - Postdoctoral Research: University Hospital Zurich, Switzerland
- 2021-Present - Specially Appointed Professor: University of Science and Technology of China
Academic Background & Achievements
- 2005 - Bachelor's Degree: Central South University
- 2008 - Master's Degree: Chengdu Institute of Biology, Chinese Academy of Sciences
- 2012 - PhD: University of Science and Technology of China
- 2021 - National Youth Talent Program Awardee
Publications
- HLA-DR15 Molecules Jointly Shape an Autoreactive T Cell Repertoire in Multiple Sclerosis, Wang J, Jelcic I, Mühlenbruch L, Haunerdinger V, Toussaint N, Zhao Y, Cruciani C, Faigle W, Naghavian R, Foege M, Binder T, Eiermann T, Opitz L, Fuentes-Font L, Reynolds R, Kwok W, Nguyen J, Lee J, Lutterotti A, Münz C, Rammensee H, Hauri-Hohl M, Sospedra M, Stevanovic S, and Martin R, 2020
- Memory B Cells Activate Brain-Homing, Autoreactive CD4(+) T Cells in Multiple Sclerosis, Jelcic I*, Al Nimer F*, Wang J, Lentsch V, Planas R, Jelcic I, Madjovski A, Ruhrmann S, Faigle W, Frauenknecht K, Pinilla C, Santos R, Hammer C, Ortiz Y, Opitz L, Grönlund H, Rogler G, Boyman O, Reynolds R, Lutterotti A, Khademi M, Olsson T, Piehl F, Sospedra M, and Martin R, 2018
- Activation of TLR Signaling in Sensitization-Recruited Inflammatory Monocytes Attenuates OVA-Induced Allergic Asthma, Huang C, Wang J*, Zheng X, Chen Y, Wei H, Sun R, and Tian Z*, 2018
- Commensal bacteria aggravate allergic asthma via NLRP3/IL-1beta signaling in post-weaning mice, Huang C, Wang J*, Zheng X, Chen Y, Zhou R, Wei H, Sun R, and Tian Z*, 2018
- Respiratory influenza virus infection induces intestinal immune injury via microbiota-mediated Th17 cell-dependent inflammation, Wang J*, Li F*, Wei H, Lian Z, Sun R, and Tian Z, 2014
- Klebsiella pneumoniae alleviates influenza-induced acute lung injury via limiting NK cell expansion, Wang J, Li F, Sun R, Gao X, Wei H, and Tian Z, 2014
- Bacterial colonization dampens influenza-mediated acute lung injury via induction of M2 alveolar macrophages, Wang J*, Li F*, Sun R, Gao X, Wei H, Li L, and Tian Z, 2013
Awards
- 2021: National Youth Talent Program Awardee
