Professor | Jian Wang | Asia Growth Partners

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Name	Jian Wang
Contact Information	ustcwj@ustc.edu.cn
Language ability	Chinese, English
Province	Anhui

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Name

Jian Wang

Contact Information

ustcwj@ustc.edu.cn

Language ability

Chinese, English

Province

Anhui

University/Lab Affiliation and Title	University of Science and Technology of China
Faculty	Basic Medical Sciences
Academic Background & Achievements	2005 - Bachelor's Degree: Central South University 2008 - Master's Degree: Chengdu Institute of Biology, Chinese Academy of Sciences 2012 - PhD: University of Science and Technology of China 2021 - National Youth Talent Program Awardee
Work Experience	2012-2015 - Postdoctoral Research: University of Science and Technology of China 2017-2021 - Postdoctoral Research: University Hospital Zurich, Switzerland 2021-Present - Specially Appointed Professor: University of Science and Technology of China
Awards	2021: National Youth Talent Program Awardee

University/Lab Affiliation and Title

University of Science and Technology of China

Faculty

Basic Medical Sciences

Academic Background & Achievements

2005 - Bachelor's Degree: Central South University
2008 - Master's Degree: Chengdu Institute of Biology, Chinese Academy of Sciences
2012 - PhD: University of Science and Technology of China
2021 - National Youth Talent Program Awardee

Work Experience

2012-2015 - Postdoctoral Research: University of Science and Technology of China
2017-2021 - Postdoctoral Research: University Hospital Zurich, Switzerland
2021-Present - Specially Appointed Professor: University of Science and Technology of China

Awards

2021: National Youth Talent Program Awardee

Areas of Focus	Identification of disease-related T cell phenotypes and functions Screening of disease-related T cell antigen epitopes and elucidation of T cell-mediated disease pathogenesis Disease treatment based on antigen epitopes and T cell receptors (TCR), such as peptide vaccines, mRNA vaccines, and TCR-T
Publications	HLA-DR15 Molecules Jointly Shape an Autoreactive T Cell Repertoire in Multiple Sclerosis, Wang J, Jelcic I, Mühlenbruch L, Haunerdinger V, Toussaint N, Zhao Y, Cruciani C, Faigle W, Naghavian R, Foege M, Binder T, Eiermann T, Opitz L, Fuentes-Font L, Reynolds R, Kwok W, Nguyen J, Lee J, Lutterotti A, Münz C, Rammensee H, Hauri-Hohl M, Sospedra M, Stevanovic S, and Martin R, 2020 Memory B Cells Activate Brain-Homing, Autoreactive CD4(+) T Cells in Multiple Sclerosis, Jelcic I, Al Nimer F, Wang J, Lentsch V, Planas R, Jelcic I, Madjovski A, Ruhrmann S, Faigle W, Frauenknecht K, Pinilla C, Santos R, Hammer C, Ortiz Y, Opitz L, Grönlund H, Rogler G, Boyman O, Reynolds R, Lutterotti A, Khademi M, Olsson T, Piehl F, Sospedra M, and Martin R, 2018 Activation of TLR Signaling in Sensitization-Recruited Inflammatory Monocytes Attenuates OVA-Induced Allergic Asthma, Huang C, Wang J, Zheng X, Chen Y, Wei H, Sun R, and Tian Z, 2018 Commensal bacteria aggravate allergic asthma via NLRP3/IL-1beta signaling in post-weaning mice, Huang C, Wang J, Zheng X, Chen Y, Zhou R, Wei H, Sun R, and Tian Z, 2018 Respiratory influenza virus infection induces intestinal immune injury via microbiota-mediated Th17 cell-dependent inflammation, Wang J, Li F, Wei H, Lian Z, Sun R, and Tian Z, 2014 Klebsiella pneumoniae alleviates influenza-induced acute lung injury via limiting NK cell expansion, Wang J, Li F, Sun R, Gao X, Wei H, and Tian Z, 2014 Bacterial colonization dampens influenza-mediated acute lung injury via induction of M2 alveolar macrophages, Wang J, Li F, Sun R, Gao X, Wei H, Li L, and Tian Z, 2013

Areas of Focus

Identification of disease-related T cell phenotypes and functions
Screening of disease-related T cell antigen epitopes and elucidation of T cell-mediated disease pathogenesis
Disease treatment based on antigen epitopes and T cell receptors (TCR), such as peptide vaccines, mRNA vaccines, and TCR-T

Publications

HLA-DR15 Molecules Jointly Shape an Autoreactive T Cell Repertoire in Multiple Sclerosis, Wang J, Jelcic I, Mühlenbruch L, Haunerdinger V, Toussaint N, Zhao Y, Cruciani C, Faigle W, Naghavian R, Foege M, Binder T, Eiermann T, Opitz L, Fuentes-Font L, Reynolds R, Kwok W, Nguyen J, Lee J, Lutterotti A, Münz C, Rammensee H, Hauri-Hohl M, Sospedra M, Stevanovic S, and Martin R, 2020
Memory B Cells Activate Brain-Homing, Autoreactive CD4(+) T Cells in Multiple Sclerosis, Jelcic I*, Al Nimer F*, Wang J, Lentsch V, Planas R, Jelcic I, Madjovski A, Ruhrmann S, Faigle W, Frauenknecht K, Pinilla C, Santos R, Hammer C, Ortiz Y, Opitz L, Grönlund H, Rogler G, Boyman O, Reynolds R, Lutterotti A, Khademi M, Olsson T, Piehl F, Sospedra M, and Martin R, 2018
Activation of TLR Signaling in Sensitization-Recruited Inflammatory Monocytes Attenuates OVA-Induced Allergic Asthma, Huang C, Wang J*, Zheng X, Chen Y, Wei H, Sun R, and Tian Z*, 2018
Commensal bacteria aggravate allergic asthma via NLRP3/IL-1beta signaling in post-weaning mice, Huang C, Wang J*, Zheng X, Chen Y, Zhou R, Wei H, Sun R, and Tian Z*, 2018
Respiratory influenza virus infection induces intestinal immune injury via microbiota-mediated Th17 cell-dependent inflammation, Wang J*, Li F*, Wei H, Lian Z, Sun R, and Tian Z, 2014
Klebsiella pneumoniae alleviates influenza-induced acute lung injury via limiting NK cell expansion, Wang J, Li F, Sun R, Gao X, Wei H, and Tian Z, 2014
Bacterial colonization dampens influenza-mediated acute lung injury via induction of M2 alveolar macrophages, Wang J*, Li F*, Sun R, Gao X, Wei H, Li L, and Tian Z, 2013

T Cells Antigen Epitopes Disease Pathogenesis Tcr Peptide Vaccines Mrna Vaccines Tcr-T Immune Response Autoimmunity Cellular Immunology

Wei Mo - Zhejiang University

Li-Xia Weng - Zhejiang University

Yanchuan Li - Nanjing Medical University

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