Professor | Yi Wang | Asia Growth Partners

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Name	Yi Wang
Contact Information	wy83@ustc.edu.cn
Language ability	English, Chinese
Province	Anhui

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Name

Yi Wang

Contact Information

wy83@ustc.edu.cn

Language ability

English, Chinese

Province

Anhui

University/Lab Affiliation and Title	University of Science and Technology of China
Faculty	Basic Medical Sciences
Academic Background & Achievements	2009 - Bachelor's Degree: University of Science and Technology of China 2014 - PhD: Li Ka Shing Faculty of Medicine, University of Hong Kong Achievement: Hong Kong SAR Young Scientist Award Joint PhD training at Cornell University, USA
Work Experience	2014 - Postdoctoral Researcher, Research Assistant Professor, Senior Assistant Researcher: Li Ka Shing Faculty of Medicine, University of Hong Kong 2019 - Independent PI: Precision Medicine Research Institute, First Affiliated Hospital of Sun Yat-sen University 2020 - Researcher: School of Life Sciences and Medicine, University of Science and Technology of China
Awards	Hong Kong SAR Young Scientist Award

University/Lab Affiliation and Title

University of Science and Technology of China

Faculty

Basic Medical Sciences

Academic Background & Achievements

2009 - Bachelor's Degree: University of Science and Technology of China
2014 - PhD: Li Ka Shing Faculty of Medicine, University of Hong Kong
Achievement: Hong Kong SAR Young Scientist Award
Joint PhD training at Cornell University, USA

Work Experience

2014 - Postdoctoral Researcher, Research Assistant Professor, Senior Assistant Researcher: Li Ka Shing Faculty of Medicine, University of Hong Kong
2019 - Independent PI: Precision Medicine Research Institute, First Affiliated Hospital of Sun Yat-sen University
2020 - Researcher: School of Life Sciences and Medicine, University of Science and Technology of China

Awards

Hong Kong SAR Young Scientist Award

Areas of Focus	Tumor Immunity of NK Cells Synthetic Immunology of NK Cells
Publications	SIRT3-dependent delactylation of cyclin E2 prevents hepatocellular carcinoma growth, Jing Jin, Lin Bai, Dongyao Wang, Wei Ding, Zhuoxian Cao, Peidong Yan, Yunjia Li, Lulu Xi, Yuxin Wang, Xiaohu Zheng, Haiming Wei, Chen Ding, Yi Wang, 2023 SIRT6 Widely Regulates Aging, Immunity, and Cancer, Yunjia Li, Jing Jin, Yi Wang, 2022 SIRT2 reverses 4-oxononanoyl lysine modification on histones, Jing Jin, Bin He, Xiaoyu Zhang, Hening Lin, Yi Wang, 2016 Identification of the YEATS domain of GAS41 as a pH-dependent reader of histone succinylation, Yi Wang, Jing Jin, Matthew Wai Heng Chung, Ling Feng, Hongyan Sun, Quan Hao, 2018 De-acylation Mechanism by SIRT2 Revealed in an Intermediate Structure, Yi Wang, Yi Man Eva Fung, Weizhe Zhang, Bin He, Matthew Wai Heng Chung, Jing Jin, Jing Hu, Hening Lin, Quan Hao, 2017 Identification of ‘erasers’ for lysine crotonylated histone marks using a chemical proteomics approach, Xiucong Bao, Yi Wang, Xin Li, Xiao-Meng Li, Zheng Liu, Tangpo Yang, Chi Fat Wong, Jiangwen Zhang, Quan Hao, Xiang David Li, 2014 SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine, Hong Jiang, Saba Khan, Yi Wang, Guillaume Charron, Bin He, Carlos Sebastian, Jin tang Du, Ray Kim, Eva Ge, Raul Mostoslavsky, Howard C. Hang, Quan Hao, Hening Lin, 2013 Lysine benzoylation is a histone mark regulated by SIRT2, He Huang, Di Zhang, Yi Wang, Mathew Perez-Neut, Zhen Han, Y. George Zheng, Quan Hao, Yingming Zhao, 2018 SIRT7 is an RNA-activated protein lysine deacylase, Zhen Tong, Miao Wang, Yi Wang, David D. Kim, Jennifer K. Grenier, Ji Cao, Sushabhan Sadhukhan, Quan Hao, Hening Lin, 2016 Fluorescent Probes for Single-Step Detection and Proteomic Profiling of Histone Deacetylases, Yusheng Xie, Jingyan Ge, Haipeng Lei, Bo Peng, Huatang Zhang, Danyang Wang, Sijun Pan, Ganchao Chen, Lanfang Chen, Yi Wang, Quan Hao, Shao Q. Yao, Hongyan Sun, 2016 SIRT7 Is Activated by DNA and Deacetylates Histone H3 in the Chromatin Context, Zhen Tong, Yi Wang, Xiaoyu Zhang, David D. Kim, Sushabhan Sadhukhan, Quan Hao, Hening Lin, 2016 Lamin A Is an Endogenous SIRT6 Activator and Promotes SIRT6-Mediated DNA Repair, Shrestha Ghosh, Baohua Liu, Yi Wang, Quan Hao, Zhongjun Zhou, 2015 Cloning, overproduction, purification, crystallization and preliminary X-ray diffraction analysis of yeast glutaredoxin Grx5, Yi Wang, Yong-Xing He, Jiang Yu, Cong-Zhao Zhou, 2009

Areas of Focus

Tumor Immunity of NK Cells
Synthetic Immunology of NK Cells

Publications

SIRT3-dependent delactylation of cyclin E2 prevents hepatocellular carcinoma growth, Jing Jin, Lin Bai, Dongyao Wang, Wei Ding, Zhuoxian Cao, Peidong Yan, Yunjia Li, Lulu Xi, Yuxin Wang, Xiaohu Zheng, Haiming Wei, Chen Ding, Yi Wang, 2023
SIRT6 Widely Regulates Aging, Immunity, and Cancer, Yunjia Li, Jing Jin, Yi Wang, 2022
SIRT2 reverses 4-oxononanoyl lysine modification on histones, Jing Jin, Bin He, Xiaoyu Zhang, Hening Lin, Yi Wang, 2016
Identification of the YEATS domain of GAS41 as a pH-dependent reader of histone succinylation, Yi Wang, Jing Jin, Matthew Wai Heng Chung, Ling Feng, Hongyan Sun, Quan Hao, 2018
De-acylation Mechanism by SIRT2 Revealed in an Intermediate Structure, Yi Wang, Yi Man Eva Fung, Weizhe Zhang, Bin He, Matthew Wai Heng Chung, Jing Jin, Jing Hu, Hening Lin, Quan Hao, 2017
Identification of ‘erasers’ for lysine crotonylated histone marks using a chemical proteomics approach, Xiucong Bao, Yi Wang, Xin Li, Xiao-Meng Li, Zheng Liu, Tangpo Yang, Chi Fat Wong, Jiangwen Zhang, Quan Hao, Xiang David Li, 2014
SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine, Hong Jiang, Saba Khan, Yi Wang, Guillaume Charron, Bin He, Carlos Sebastian, Jin tang Du, Ray Kim, Eva Ge, Raul Mostoslavsky, Howard C. Hang, Quan Hao, Hening Lin, 2013
Lysine benzoylation is a histone mark regulated by SIRT2, He Huang, Di Zhang, Yi Wang, Mathew Perez-Neut, Zhen Han, Y. George Zheng, Quan Hao, Yingming Zhao, 2018
SIRT7 is an RNA-activated protein lysine deacylase, Zhen Tong, Miao Wang, Yi Wang, David D. Kim, Jennifer K. Grenier, Ji Cao, Sushabhan Sadhukhan, Quan Hao, Hening Lin, 2016
Fluorescent Probes for Single-Step Detection and Proteomic Profiling of Histone Deacetylases, Yusheng Xie, Jingyan Ge, Haipeng Lei, Bo Peng, Huatang Zhang, Danyang Wang, Sijun Pan, Ganchao Chen, Lanfang Chen, Yi Wang, Quan Hao, Shao Q. Yao, Hongyan Sun, 2016
SIRT7 Is Activated by DNA and Deacetylates Histone H3 in the Chromatin Context, Zhen Tong, Yi Wang, Xiaoyu Zhang, David D. Kim, Sushabhan Sadhukhan, Quan Hao, Hening Lin, 2016
Lamin A Is an Endogenous SIRT6 Activator and Promotes SIRT6-Mediated DNA Repair, Shrestha Ghosh, Baohua Liu, Yi Wang, Quan Hao, Zhongjun Zhou, 2015
Cloning, overproduction, purification, crystallization and preliminary X-ray diffraction analysis of yeast glutaredoxin Grx5, Yi Wang, Yong-Xing He, Jiang Yu, Cong-Zhao Zhou, 2009

Nk Cells Tumor Immunity Tumor Microenvironment New Mechanisms New Targets Drug Development Anti-Tumor Effects Synthetic Biology Clinical Immunotherapy Precision Targeting

Wenling Han - Peking University

Wenjun Guan - Zhejiang University

Lan Wang - Fudan University

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