Professor | 王毅 | 数字化转型顾问

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Name	王毅
Contact Information	wy83@ustc.edu.cn
Language ability	英语, 中文
Province	安徽

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Name

王毅

Contact Information

wy83@ustc.edu.cn

Language ability

英语, 中文

Province

安徽

University/Lab Affiliation and Title	中国科学技术大学
Faculty	Basic Medical Sciences
Academic Background & Achievements	2009 - 学士学位: 中国科学技术大学 2014 - 博士学位: 香港大学李嘉诚医学院成就: 香港特别行政区青年科学家奖博士联合培养于美国康奈尔大学
Work Experience	2014 - 博士后、研究助理教授、高级助理研究员: 香港大学李嘉诚医学院 2019 - 独立PI: 中山大学附属第一医院精准医学研究院 2020 - 研究员: 中国科学技术大学生命科学与医学部
Awards	香港特别行政区青年科学家奖

University/Lab Affiliation and Title

中国科学技术大学

Faculty

Basic Medical Sciences

Academic Background & Achievements

2009 - 学士学位: 中国科学技术大学
2014 - 博士学位: 香港大学李嘉诚医学院
成就: 香港特别行政区青年科学家奖
博士联合培养于美国康奈尔大学

Work Experience

2014 - 博士后、研究助理教授、高级助理研究员: 香港大学李嘉诚医学院
2019 - 独立PI: 中山大学附属第一医院精准医学研究院
2020 - 研究员: 中国科学技术大学生命科学与医学部

Awards

香港特别行政区青年科学家奖

Areas of Focus	NK细胞的肿瘤免疫 NK细胞合成免疫学
Publications	SIRT3-dependent delactylation of cyclin E2 prevents hepatocellular carcinoma growth, Jing Jin, Lin Bai, Dongyao Wang, Wei Ding, Zhuoxian Cao, Peidong Yan, Yunjia Li, Lulu Xi, Yuxin Wang, Xiaohu Zheng, Haiming Wei, Chen Ding, Yi Wang, 2023 SIRT6 Widely Regulates Aging, Immunity, and Cancer, Yunjia Li, Jing Jin, Yi Wang, 2022 SIRT2 reverses 4-oxononanoyl lysine modification on histones, Jing Jin, Bin He, Xiaoyu Zhang, Hening Lin, Yi Wang, 2016 Identification of the YEATS domain of GAS41 as a pH-dependent reader of histone succinylation, Yi Wang, Jing Jin, Matthew Wai Heng Chung, Ling Feng, Hongyan Sun, Quan Hao, 2018 De-acylation Mechanism by SIRT2 Revealed in an Intermediate Structure, Yi Wang, Yi Man Eva Fung, Weizhe Zhang, Bin He, Matthew Wai Heng Chung, Jing Jin, Jing Hu, Hening Lin, Quan Hao, 2017 Identification of ‘erasers’ for lysine crotonylated histone marks using a chemical proteomics approach, Xiucong Bao, Yi Wang, Xin Li, Xiao-Meng Li, Zheng Liu, Tangpo Yang, Chi Fat Wong, Jiangwen Zhang, Quan Hao, Xiang David Li, 2014 SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine, Hong Jiang, Saba Khan, Yi Wang, Guillaume Charron, Bin He, Carlos Sebastian, Jin tang Du, Ray Kim, Eva Ge, Raul Mostoslavsky, Howard C. Hang, Quan Hao, Hening Lin, 2013 Lysine benzoylation is a histone mark regulated by SIRT2, He Huang, Di Zhang, Yi Wang, Mathew Perez-Neut, Zhen Han, Y. George Zheng, Quan Hao, Yingming Zhao, 2018 SIRT7 is an RNA-activated protein lysine deacylase, Zhen Tong, Miao Wang, Yi Wang, David D. Kim, Jennifer K. Grenier, Ji Cao, Sushabhan Sadhukhan, Quan Hao, Hening Lin, 2016 Fluorescent Probes for Single-Step Detection and Proteomic Profiling of Histone Deacetylases, Yusheng Xie, Jingyan Ge, Haipeng Lei, Bo Peng, Huatang Zhang, Danyang Wang, Sijun Pan, Ganchao Chen, Lanfang Chen, Yi Wang, Quan Hao, Shao Q. Yao, Hongyan Sun, 2016 SIRT7 Is Activated by DNA and Deacetylates Histone H3 in the Chromatin Context, Zhen Tong, Yi Wang, Xiaoyu Zhang, David D. Kim, Sushabhan Sadhukhan, Quan Hao, Hening Lin, 2016 Lamin A Is an Endogenous SIRT6 Activator and Promotes SIRT6-Mediated DNA Repair, Shrestha Ghosh, Baohua Liu, Yi Wang, Quan Hao, Zhongjun Zhou, 2015 Cloning, overproduction, purification, crystallization and preliminary X-ray diffraction analysis of yeast glutaredoxin Grx5, Yi Wang, Yong-Xing He, Jiang Yu, Cong-Zhao Zhou, 2009

Areas of Focus

NK细胞的肿瘤免疫
NK细胞合成免疫学

Publications

SIRT3-dependent delactylation of cyclin E2 prevents hepatocellular carcinoma growth, Jing Jin, Lin Bai, Dongyao Wang, Wei Ding, Zhuoxian Cao, Peidong Yan, Yunjia Li, Lulu Xi, Yuxin Wang, Xiaohu Zheng, Haiming Wei, Chen Ding, Yi Wang, 2023
SIRT6 Widely Regulates Aging, Immunity, and Cancer, Yunjia Li, Jing Jin, Yi Wang, 2022
SIRT2 reverses 4-oxononanoyl lysine modification on histones, Jing Jin, Bin He, Xiaoyu Zhang, Hening Lin, Yi Wang, 2016
Identification of the YEATS domain of GAS41 as a pH-dependent reader of histone succinylation, Yi Wang, Jing Jin, Matthew Wai Heng Chung, Ling Feng, Hongyan Sun, Quan Hao, 2018
De-acylation Mechanism by SIRT2 Revealed in an Intermediate Structure, Yi Wang, Yi Man Eva Fung, Weizhe Zhang, Bin He, Matthew Wai Heng Chung, Jing Jin, Jing Hu, Hening Lin, Quan Hao, 2017
Identification of ‘erasers’ for lysine crotonylated histone marks using a chemical proteomics approach, Xiucong Bao, Yi Wang, Xin Li, Xiao-Meng Li, Zheng Liu, Tangpo Yang, Chi Fat Wong, Jiangwen Zhang, Quan Hao, Xiang David Li, 2014
SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine, Hong Jiang, Saba Khan, Yi Wang, Guillaume Charron, Bin He, Carlos Sebastian, Jin tang Du, Ray Kim, Eva Ge, Raul Mostoslavsky, Howard C. Hang, Quan Hao, Hening Lin, 2013
Lysine benzoylation is a histone mark regulated by SIRT2, He Huang, Di Zhang, Yi Wang, Mathew Perez-Neut, Zhen Han, Y. George Zheng, Quan Hao, Yingming Zhao, 2018
SIRT7 is an RNA-activated protein lysine deacylase, Zhen Tong, Miao Wang, Yi Wang, David D. Kim, Jennifer K. Grenier, Ji Cao, Sushabhan Sadhukhan, Quan Hao, Hening Lin, 2016
Fluorescent Probes for Single-Step Detection and Proteomic Profiling of Histone Deacetylases, Yusheng Xie, Jingyan Ge, Haipeng Lei, Bo Peng, Huatang Zhang, Danyang Wang, Sijun Pan, Ganchao Chen, Lanfang Chen, Yi Wang, Quan Hao, Shao Q. Yao, Hongyan Sun, 2016
SIRT7 Is Activated by DNA and Deacetylates Histone H3 in the Chromatin Context, Zhen Tong, Yi Wang, Xiaoyu Zhang, David D. Kim, Sushabhan Sadhukhan, Quan Hao, Hening Lin, 2016
Lamin A Is an Endogenous SIRT6 Activator and Promotes SIRT6-Mediated DNA Repair, Shrestha Ghosh, Baohua Liu, Yi Wang, Quan Hao, Zhongjun Zhou, 2015
Cloning, overproduction, purification, crystallization and preliminary X-ray diffraction analysis of yeast glutaredoxin Grx5, Yi Wang, Yong-Xing He, Jiang Yu, Cong-Zhao Zhou, 2009

Nk细胞肿瘤免疫肿瘤微环境新机制新靶点药物研发抗肿瘤效应合成生物学临床免疫治疗精准靶向

郑小虎 - 中国科学技术大学

卢颖 - 复旦大学

赵亮 - 南方医科大学

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