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Chen Yongyan
Basic Medical Sciences
University of Science and Technology of China
Anhui
Language: Chinese, English
Hbv
Hepatocellular Carcinoma
Immune Exhaustion
Reversal Mechanisms
Liver
Immune Tolerance
Microenvironment
Metastases
Cancer
Immunology
Areas of Focus
- Immune exhaustion and reversal mechanisms in HBV-related hepatocellular carcinoma
- Role and mechanisms of liver immune tolerance microenvironment in the development of liver metastases
Work Experience
- 2013-2017 - Vice Chairman of the Youth Working Committee, Chinese Society of Immunology
- 2015-present - Corresponding Editor, Chinese Journal of Clinical Rheumatology and Immunology
- 2015.9-present - Vice Chairman (part-time), Science and Technology Association of Shushan District, Hefei
- Review Editor, Front Immunol
Academic Background & Achievements
- 2001 - Bachelor of Medicine: Shandong University
- 2007 - Doctor of Science: University of Science and Technology of China
- Published over 50 SCI-indexed papers
Publications
- UGRP1-Modulated MARCO + Alveolar Macrophages Contribute to Age-Related Lung Fibrosis, Chen Y*, Hao X, Li M, Tian Z, Cheng M*, 2023
- Blockade of T-cell receptor with Ig and ITIM domains elicits potent antitumor immunity in naturally occurring HBV-related HCC in mice, Wu Y, Hao X, Wei H, Sun R*, Chen Y*, Tian Z*, 2023
- CD11b+ CD43hi Ly6Clo splenocyte-derived macrophages exacerbate liver fibrosis via spleen-liver axis, Zhang S, Wan D, Zhu M, Wang G, Zhang X, Huang N, Zhang J, Zhang C, Shang Q, Zhang C, Liu X, Liang F, Zhang C, Kong G, Geng J, Yao L, Lu S*, Chen Y*, Li Z*, 2023
- HBV immune tolerance of HBs-transgenic mice observed through parabiosis with WT mice, Zhang W, Sun H, Sun R, Lian Z, Wei H, Tian Z*, Chen Y*, 2022
- Natural Killer Cell-Derived Interferon-Gamma Promotes Hepatocellular Carcinoma Through the Epithelial Cell Adhesion Molecule-Epithelial-to-Mesenchymal Transition Axis in Hepatitis B Virus Transgenic Mice, Chen Y*, Hao X, Sun R, Wei H, Tian Z*, 2019
Awards
- 2008: First 'China Immunology Young Scholar Award'
- 2018: Second Prize, Anhui Province Undergraduate Teaching Achievement Award
- 2019: Anhui Provincial Teaching Rookie
- 2022: First Prize, Anhui Province Graduate Teaching Achievement Award
