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Yanhui Yin
Basic Medical Sciences
Peking University
Beijing
Language: English, Chinese
Immunotherapy
Cancer
Tumor Antigens
Microenvironment
Mechanisms
Cell Therapy
Antigen Roles
Tumor Environment
Cancer Research
Clinical Trials
Areas of Focus
- Immunotherapy for cancer
- Role and mechanisms of tumor antigens in tumor microenvironment
Work Experience
- 1999-2001 - Visiting Scholar, Tokushima University, Japan
- Current - Associate Professor, Department of Immunology, Peking University Medical School
Academic Background & Achievements
- 1993 - Bachelor of Medicine in English Medical Program, Norman Bethune College of Medicine
- 1996 - Master's Degree in Immunology, Norman Bethune College of Medicine
- 2001 - PhD in Immunology, Jilin University
- 2005 - Postdoctoral Research, Department of Immunology, Peking University Medical School
Publications
- Post-transcriptional regulation of cancer/testis antigen MAGEC2 expression by TRIM28 in tumor cells, Yanhui Yin*, 2018
- Cancer-testis antigen HCA587/MAGEC2 interacts with the general transcription coactivator TAF9 in cancer cells, Yanhui Yin*, 2018
- The cancer/testis antigen MAGEC2 promotes amoeboid invasion of tumor cells by enhancing STAT3 signaling, Yanhui Yin*, 2017
- Establishment of MAGEC2-knockout cells and functional investigation of MAGEC2 in tumor cells, Yanhui Yin*, 2016
- MicroRNA-874 functions as a tumor suppressor by targeting cancer/testis antigen HCA587/MAGE-C2, Yanhui Yin*, 2016
- Cancer-testis antigen MAGE-C2 binds Rbx1 and inhibits ubiquitin ligase-mediated turnover of cyclin E, Yanhui Yin*, 2015
- Identification of a FOXP3(+)CD3(+)CD56(+) population with immunosuppressive function in cancer tissues of human hepatocellular carcinoma, Yanhui Yin*, 2015
- Evaluation of KF23 variant 1 expression and relevance as a novel prognostic factor in patients with hepatocellular carcinoma, Yanhui Yin*, 2015
- Cancer-testis antigen HCA587/MAGE-C2 interacts with BS69 and promotes its degradation in the ubiquitin-proteasome pathway, Yanhui Yin*, 2014
- Cancer/Testis antigen HCA587-derived long peptide vaccine generates potent immunologic responses and antitumor effects in mouse model, Yanhui Yin*, 2014
Awards
- 2008 - Outstanding Young Scholar, Peking University Medical School
- National Education Ministry Natural Science Award, First Prize
- Chinese Medical Science and Technology Award, Second Prize
- Beijing Science and Technology Award, Second Prize
