Areas of Focus
- 肿瘤的免疫细胞治疗
- 肿瘤抗原在肿瘤微环境形成中的作用及其机制
Work Experience
- 1999-2001年 - 日本德岛大学访问学者
- 现任 - 北京大学医学部免疫学系副教授
Academic Background & Achievements
- 1993年 - 白求恩医科大学英语医学专业获医学学士学位
- 1996年 - 白求恩医科大学免疫教研室获硕士学位
- 2001年 - 吉林大学免疫教研室获博士学位
- 2005年 - 北京大学医学部免疫学系博士后
Publications
- Post-transcriptional regulation of cancer/testis antigen MAGEC2 expression by TRIM28 in tumor cells, 尹艳慧*, 2018
- Cancer-testis antigen HCA587/MAGEC2 interacts with the general transcription coactivator TAF9 in cancer cells, 尹艳慧*, 2018
- The cancer/testis antigen MAGEC2 promotes amoeboid invasion of tumor cells by enhancing STAT3 signaling, 尹艳慧*, 2017
- Establishment of MAGEC2-knockout cells and functional investigation of MAGEC2 in tumor cells, 尹艳慧*, 2016
- MicroRNA-874 functions as a tumor suppressor by targeting cancer/testis antigen HCA587/MAGE-C2, 尹艳慧*, 2016
- Cancer-testis antigen MAGE-C2 binds Rbx1 and inhibits ubiquitin ligase-mediated turnover of cyclin E, 尹艳慧*, 2015
- Identification of a FOXP3(+)CD3(+)CD56(+) population with immunosuppressive function in cancer tissues of human hepatocellular carcinoma, 尹艳慧*, 2015
- Evaluation of KF23 variant 1 expression and relevance as a novel prognostic factor in patients with hepatocellular carcinoma, 尹艳慧*, 2015
- Cancer-testis antigen HCA587/MAGE-C2 interacts with BS69 and promotes its degradation in the ubiquitin-proteasome pathway, 尹艳慧*, 2014
- Cancer/Testis antigen HCA587-derived long peptide vaccine generates potent immunologic responses and antitumor effects in mouse model, 尹艳慧*, 2014
Awards
- 2008年 - 北京大学医学部优秀青年学者
- 国家教育部自然科学奖一等奖
- 中华医学科技奖二等奖
- 北京市科学技术奖二等奖