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Yang Li
Basic Medical Sciences
Peking University
Beijing
Language: Chinese, English
Pluripotent Stem Cells
Rare Diseases
Cell Differentiation
Molecular Regulation
Nk Cells
T Cells
Cancer
Immunotherapy
Stem Cell Therapy
Cellular Models
Areas of Focus
- Construction of rare disease models using human pluripotent stem cells (ES, iPS)
- Molecular regulation mechanisms of human pluripotent stem cell differentiation
- Application of directed NK and T cell differentiation from human pluripotent stem cells in cancer immunotherapy
Work Experience
- 2007 - Present - Peking University, Associate Professor
Academic Background & Achievements
- 2000 - Bachelor's Degree in Bioengineering from Inner Mongolia Agricultural University
- 2003 - Master's Degree in Reproductive Biology from Inner Mongolia University, studied under Academician Xuri Gan
- 2007 - PhD in Stem Cell Biology from Peking University, studied under Professor Lingsong Li
- Postdoctoral training at Sunnybrook Research Institute, University of Toronto, under Professor Juan Carlos Zuniga-Pflucker
Publications
- NAT10-mediated N4-acetylcytidine mRNA modification regulates self-renewal in human embryonic stem cells, Liu R, Wubulikasimu Z, Cai R, Meng F, Cui Q, Zhou Y, Li Y, 2023
- Leveraging CD16 fusion receptors to remodel the immune response for enhancing anti-tumor immunotherapy in iPSC-derived NK cells, Meng F, Zhang S, Xie J, Zhou Y, Wu Q, Lu B, Zhou S, Zhao X, Li Y, 2023
- MFN2 knockdown promotes osteogenic differentiation of iPSC-MSCs through aerobic glycolysis mediated by the Wnt/β-catenin signaling pathway, Deng L, Yi S, Yin X, Li Y, Luan Q, 2022
- T-cell receptor β-selection is required at the CD4+CD8+ stage of human T cell development, Chen E, Brauer P, Martinez E, Huang X, Yu Y, Anderson M, Li Y, Juan Carlos Zuniga-Pflucker JC, 2021
- Cellular uptake of a cationic amphiphilic fluorophore in the form of assemblies via Clathrin-dependent endocytosis, Zhou S, Wu J, Huang X, Yu N, Zou X, Singh J, Bo Song B, Li Y, 2021
- E2A regulates neural ectoderm fate specification in human embryonic stem cells, Yi S, Huang X, Zhou Y, Zhou S, Anderson M, Juan Carlos Zuniga-Pflucker JC, Luan Q, Li Y, 2020
- Application of amphiphilic fluorophore-derived nanoparticles to provide contrast to human embryonic stem cells without affecting their pluripotency and to monitor their differentiation into neuron-like cells, Zhou S, Zhao H, Feng R, Ding L, Li Z, Deng C, He Q, Liu Y, Song B, Li Y, 2018
- Targeted disruption in TCF12 reveals HEB as an essential for human mesodermal specification and hematopoiesis, Li Y, Brauer P, Jastaranpreet S, Xhiku S, Yoganathan K, Juan Carlos Zuniga-Pflucker JC, Anderson M, 2017
- HMDD v2.0: a database for experimentally supported human microRNA and disease association, Li Y, Qiu C, Tu J, Geng B, Yang J, Jiang T, Cui Q, 2014
- Efficient induction of pluripotent stem cells from menstrual blood, Li Y, Li X, Zhao H, Feng R, Zhang X, Tan J, 2013
- Comparison of three methods for cryopreservation of human embryonic stem cells, Li Y, Tan J, Li L, 2010
Awards
- 2022: Second place in the project 'Autologous menstrual blood-derived mesenchymal stem cell therapy for uterine adhesions' which won the Third Prize of the China Medical Science and Technology Award
