Professor | Chuang Guo | Asia Growth Partners

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Name	Chuang Guo
Contact Information	gchuang@ustc.edu.cn
Language ability	Chinese, English
Province	Anhui

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Name

Chuang Guo

Contact Information

gchuang@ustc.edu.cn

Language ability

Chinese, English

Province

Anhui

University/Lab Affiliation and Title	University of Science and Technology of China
Faculty	Basic Medical Sciences
Academic Background & Achievements	2009-2016 PhD in Immunology: University of Science and Technology of China 2005-2009 Bachelor's in Biological Sciences: University of Science and Technology of China
Work Experience	2023.04 - Present - University of Science and Technology of China - Associate Professor 2022.01 - Present - The First Affiliated Hospital of USTC - Distinguished Expert 2019.02 - 2023.03 - University of Science and Technology of China - Special Associate Researcher 2016.10 - 2019.01 - University of Science and Technology of China - Postdoctoral Researcher in Bioinformatics

University/Lab Affiliation and Title

University of Science and Technology of China

Faculty

Basic Medical Sciences

Academic Background & Achievements

2009-2016 PhD in Immunology: University of Science and Technology of China
2005-2009 Bachelor's in Biological Sciences: University of Science and Technology of China

Work Experience

2023.04 - Present - University of Science and Technology of China - Associate Professor
2022.01 - Present - The First Affiliated Hospital of USTC - Distinguished Expert
2019.02 - 2023.03 - University of Science and Technology of China - Special Associate Researcher
2016.10 - 2019.01 - University of Science and Technology of China - Postdoctoral Researcher in Bioinformatics

Areas of Focus	Application of single-cell omics and bioinformatics analysis algorithms Functional characteristics and pathogenic mechanisms of immune cell subsets in autoimmune diseases Potential targets for clinical diagnosis and treatment based on circular DNA
Publications	Benchmarking spatial and single-cell transcriptomics integration methods for transcript distribution prediction and cell type deconvolution., Bin Li, Wen Zhang, Chuang Guo, Hao Xu, Longfei Li, Minghao Fang, Yinlei Hu, Xinye Zhang, Xinfeng Yao, Meifang Tang, Ke Liu, Xuetong Zhao, Jun Lin, Linzhao Cheng, Falai Chen, Tian Xue, Kun Qu, 2022 Single-cell transcriptomics reveal a unique memory-like NK cell subset that accumulates with ageing and correlates with disease severity in COVID-19., Chuang Guo, Mingming Wu, Beibei Huang, Rui Zhao, Linlin Jin, Binqing Fu, Ping Wang, Dongyao Wang, Meijuan Zheng, Jingwen Fang, Haiming Wei, Kun Qu, Fang Ni, 2022 Single-cell transcriptome and chromatin accessibility profiling reveal an exhausted regulatory CD4+ T cell subset in systemic lupus erythematosus., Chuang Guo, Qian Liu, Dandan Zong, Wen Zhang, Zuqi Zuo, Qiaoni Yu, Qing Sha, Lin Zhu, Xuyuan Gao, Jingwen Fang, Jinhui Tao, Quan Wu, Xiaomei Li, Kun Qu, 2022 A transcriptome atlas and interactive analysis platform for autoimmune disease., Zhuoqiao Shen, Minghao Fang, Wujianan Sun, Meifang Tang, Nianping Liu, Lin Zhu, Qian Liu, Bin Li, Ruoming Sun, Yu Shi, Chuang Guo, Jun Lin, Kun Qu, 2022 Single-cell profiling of the human decidual immune microenvironment in patients with recurrent pregnancy loss., Chuang Guo, Pengfei Cai, Liying Jin, Qing Sha, Qiaoni Yu, Wen Zhang, Chen Jiang, Qian Liu, Dandan Zong, Kun Li, Jingwen Fang, Fangting Lu, Yanshi Wang, Daojing Li, Jun Lin, Lu Li, Zhutian Zeng, Xianhong Tong, Haiming Wei, Kun Qu, 2021 Single-cell analysis of COVID-19, sepsis, and HIV infection reveals hyperinflammatory and immunosuppressive signatures in monocytes., Nianping Liu, Chen Jiang, Pengfei Cai, Zhuoqiao Shen, Wujianan Sun, Hao Xu, Minghao Fang, Xinfeng Yao, Lin Zhu, Xuyuan Gao, Jingwen Fang, Jun Lin, Chuang Guo, Kun Qu, 2021 Single-cell analysis of two severe COVID-19 patients reveals a monocyte-associated and tocilizumab-responding cytokine storm., Chuang Guo, Bin Li, Huan Ma, Xiaofang Wang, Pengfei Cai, Qiaoni Yu, Lin Zhu, Liying Jin, Chen Jiang, Jingwen Fang, Qian Liu, Dandan Zong, Wen Zhang, Yichen Lu, Kun Li, Xuyuan Gao, Binqing Fu, Lianxin Liu, Xiaoling Ma, Jianping Weng, Haiming Wei, Tengchuan Jin, Jun Lin, Kun Qu, 2020

Areas of Focus

Application of single-cell omics and bioinformatics analysis algorithms
Functional characteristics and pathogenic mechanisms of immune cell subsets in autoimmune diseases
Potential targets for clinical diagnosis and treatment based on circular DNA

Publications

Benchmarking spatial and single-cell transcriptomics integration methods for transcript distribution prediction and cell type deconvolution., Bin Li, Wen Zhang, Chuang Guo, Hao Xu, Longfei Li, Minghao Fang, Yinlei Hu, Xinye Zhang, Xinfeng Yao, Meifang Tang, Ke Liu, Xuetong Zhao, Jun Lin, Linzhao Cheng, Falai Chen, Tian Xue, Kun Qu, 2022
Single-cell transcriptomics reveal a unique memory-like NK cell subset that accumulates with ageing and correlates with disease severity in COVID-19., Chuang Guo, Mingming Wu, Beibei Huang, Rui Zhao, Linlin Jin, Binqing Fu, Ping Wang, Dongyao Wang, Meijuan Zheng, Jingwen Fang, Haiming Wei, Kun Qu, Fang Ni, 2022
Single-cell transcriptome and chromatin accessibility profiling reveal an exhausted regulatory CD4+ T cell subset in systemic lupus erythematosus., Chuang Guo, Qian Liu, Dandan Zong, Wen Zhang, Zuqi Zuo, Qiaoni Yu, Qing Sha, Lin Zhu, Xuyuan Gao, Jingwen Fang, Jinhui Tao, Quan Wu, Xiaomei Li, Kun Qu, 2022
A transcriptome atlas and interactive analysis platform for autoimmune disease., Zhuoqiao Shen, Minghao Fang, Wujianan Sun, Meifang Tang, Nianping Liu, Lin Zhu, Qian Liu, Bin Li, Ruoming Sun, Yu Shi, Chuang Guo, Jun Lin, Kun Qu, 2022
Single-cell profiling of the human decidual immune microenvironment in patients with recurrent pregnancy loss., Chuang Guo, Pengfei Cai, Liying Jin, Qing Sha, Qiaoni Yu, Wen Zhang, Chen Jiang, Qian Liu, Dandan Zong, Kun Li, Jingwen Fang, Fangting Lu, Yanshi Wang, Daojing Li, Jun Lin, Lu Li, Zhutian Zeng, Xianhong Tong, Haiming Wei, Kun Qu, 2021
Single-cell analysis of COVID-19, sepsis, and HIV infection reveals hyperinflammatory and immunosuppressive signatures in monocytes., Nianping Liu, Chen Jiang, Pengfei Cai, Zhuoqiao Shen, Wujianan Sun, Hao Xu, Minghao Fang, Xinfeng Yao, Lin Zhu, Xuyuan Gao, Jingwen Fang, Jun Lin, Chuang Guo, Kun Qu, 2021
Single-cell analysis of two severe COVID-19 patients reveals a monocyte-associated and tocilizumab-responding cytokine storm., Chuang Guo, Bin Li, Huan Ma, Xiaofang Wang, Pengfei Cai, Qiaoni Yu, Lin Zhu, Liying Jin, Chen Jiang, Jingwen Fang, Qian Liu, Dandan Zong, Wen Zhang, Yichen Lu, Kun Li, Xuyuan Gao, Binqing Fu, Lianxin Liu, Xiaoling Ma, Jianping Weng, Haiming Wei, Tengchuan Jin, Jun Lin, Kun Qu, 2020

Single-Cell Omics Bioinformatics Immune Cell Subsets Autoimmune Diseases Pathogenic Mechanisms Circular Dna Clinical Diagnosis Treatment Targets Data Analysis Immunology

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