Professor | 郭闯 | 数字化转型顾问

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Name	郭闯
Contact Information	gchuang@ustc.edu.cn
Language ability	中文, 英语
Province	安徽

Upload Avatar (500 x 500)

Name

郭闯

Contact Information

gchuang@ustc.edu.cn

Language ability

中文, 英语

Province

安徽

University/Lab Affiliation and Title	中国科学技术大学
Faculty	Basic Medical Sciences
Academic Background & Achievements	2009-2016 博士学位，免疫学方向：中国科学技术大学 2005-2009 学士学位，生物科学：中国科学技术大学
Work Experience	2023.04 - 至今 - 中国科学技术大学 - 副教授 2022.01 - 至今 - 中国科学技术大学附属第一医院 - 特聘专家 2019.02 - 2023.03 - 中国科学技术大学 - 特任副研究员 2016.10 - 2019.01 - 中国科学技术大学 - 博士后，生物信息学

University/Lab Affiliation and Title

中国科学技术大学

Faculty

Basic Medical Sciences

Academic Background & Achievements

2009-2016 博士学位，免疫学方向：中国科学技术大学
2005-2009 学士学位，生物科学：中国科学技术大学

Work Experience

2023.04 - 至今 - 中国科学技术大学 - 副教授
2022.01 - 至今 - 中国科学技术大学附属第一医院 - 特聘专家
2019.02 - 2023.03 - 中国科学技术大学 - 特任副研究员
2016.10 - 2019.01 - 中国科学技术大学 - 博士后，生物信息学

Areas of Focus	单细胞组学前沿技术及生物信息学分析算法应用自身免疫病等重要疾病免疫细胞亚群功能特征及致病机制基于环状DNA临床诊疗的潜在靶点研究
Publications	Benchmarking spatial and single-cell transcriptomics integration methods for transcript distribution prediction and cell type deconvolution., Bin Li, Wen Zhang, Chuang Guo, Hao Xu, Longfei Li, Minghao Fang, Yinlei Hu, Xinye Zhang, Xinfeng Yao, Meifang Tang, Ke Liu, Xuetong Zhao, Jun Lin, Linzhao Cheng, Falai Chen, Tian Xue, Kun Qu, 2022 Single-cell transcriptomics reveal a unique memory-like NK cell subset that accumulates with ageing and correlates with disease severity in COVID-19., Chuang Guo, Mingming Wu, Beibei Huang, Rui Zhao, Linlin Jin, Binqing Fu, Ping Wang, Dongyao Wang, Meijuan Zheng, Jingwen Fang, Haiming Wei, Kun Qu, Fang Ni, 2022 Single-cell transcriptome and chromatin accessibility profiling reveal an exhausted regulatory CD4+ T cell subset in systemic lupus erythematosus., Chuang Guo, Qian Liu, Dandan Zong, Wen Zhang, Zuqi Zuo, Qiaoni Yu, Qing Sha, Lin Zhu, Xuyuan Gao, Jingwen Fang, Jinhui Tao, Quan Wu, Xiaomei Li, Kun Qu, 2022 A transcriptome atlas and interactive analysis platform for autoimmune disease., Zhuoqiao Shen, Minghao Fang, Wujianan Sun, Meifang Tang, Nianping Liu, Lin Zhu, Qian Liu, Bin Li, Ruoming Sun, Yu Shi, Chuang Guo, Jun Lin, Kun Qu, 2022 Single-cell profiling of the human decidual immune microenvironment in patients with recurrent pregnancy loss., Chuang Guo, Pengfei Cai, Liying Jin, Qing Sha, Qiaoni Yu, Wen Zhang, Chen Jiang, Qian Liu, Dandan Zong, Kun Li, Jingwen Fang, Fangting Lu, Yanshi Wang, Daojing Li, Jun Lin, Lu Li, Zhutian Zeng, Xianhong Tong, Haiming Wei, Kun Qu, 2021 Single-cell analysis of COVID-19, sepsis, and HIV infection reveals hyperinflammatory and immunosuppressive signatures in monocytes., Nianping Liu, Chen Jiang, Pengfei Cai, Zhuoqiao Shen, Wujianan Sun, Hao Xu, Minghao Fang, Xinfeng Yao, Lin Zhu, Xuyuan Gao, Jingwen Fang, Jun Lin, Chuang Guo, Kun Qu, 2021 Single-cell analysis of two severe COVID-19 patients reveals a monocyte-associated and tocilizumab-responding cytokine storm., Chuang Guo, Bin Li, Huan Ma, Xiaofang Wang, Pengfei Cai, Qiaoni Yu, Lin Zhu, Liying Jin, Chen Jiang, Jingwen Fang, Qian Liu, Dandan Zong, Wen Zhang, Yichen Lu, Kun Li, Xuyuan Gao, Binqing Fu, Lianxin Liu, Xiaoling Ma, Jianping Weng, Haiming Wei, Tengchuan Jin, Jun Lin, Kun Qu, 2020

Areas of Focus

单细胞组学前沿技术及生物信息学分析算法应用
自身免疫病等重要疾病免疫细胞亚群功能特征及致病机制
基于环状DNA临床诊疗的潜在靶点研究

Publications

Benchmarking spatial and single-cell transcriptomics integration methods for transcript distribution prediction and cell type deconvolution., Bin Li, Wen Zhang, Chuang Guo, Hao Xu, Longfei Li, Minghao Fang, Yinlei Hu, Xinye Zhang, Xinfeng Yao, Meifang Tang, Ke Liu, Xuetong Zhao, Jun Lin, Linzhao Cheng, Falai Chen, Tian Xue, Kun Qu, 2022
Single-cell transcriptomics reveal a unique memory-like NK cell subset that accumulates with ageing and correlates with disease severity in COVID-19., Chuang Guo, Mingming Wu, Beibei Huang, Rui Zhao, Linlin Jin, Binqing Fu, Ping Wang, Dongyao Wang, Meijuan Zheng, Jingwen Fang, Haiming Wei, Kun Qu, Fang Ni, 2022
Single-cell transcriptome and chromatin accessibility profiling reveal an exhausted regulatory CD4+ T cell subset in systemic lupus erythematosus., Chuang Guo, Qian Liu, Dandan Zong, Wen Zhang, Zuqi Zuo, Qiaoni Yu, Qing Sha, Lin Zhu, Xuyuan Gao, Jingwen Fang, Jinhui Tao, Quan Wu, Xiaomei Li, Kun Qu, 2022
A transcriptome atlas and interactive analysis platform for autoimmune disease., Zhuoqiao Shen, Minghao Fang, Wujianan Sun, Meifang Tang, Nianping Liu, Lin Zhu, Qian Liu, Bin Li, Ruoming Sun, Yu Shi, Chuang Guo, Jun Lin, Kun Qu, 2022
Single-cell profiling of the human decidual immune microenvironment in patients with recurrent pregnancy loss., Chuang Guo, Pengfei Cai, Liying Jin, Qing Sha, Qiaoni Yu, Wen Zhang, Chen Jiang, Qian Liu, Dandan Zong, Kun Li, Jingwen Fang, Fangting Lu, Yanshi Wang, Daojing Li, Jun Lin, Lu Li, Zhutian Zeng, Xianhong Tong, Haiming Wei, Kun Qu, 2021
Single-cell analysis of COVID-19, sepsis, and HIV infection reveals hyperinflammatory and immunosuppressive signatures in monocytes., Nianping Liu, Chen Jiang, Pengfei Cai, Zhuoqiao Shen, Wujianan Sun, Hao Xu, Minghao Fang, Xinfeng Yao, Lin Zhu, Xuyuan Gao, Jingwen Fang, Jun Lin, Chuang Guo, Kun Qu, 2021
Single-cell analysis of two severe COVID-19 patients reveals a monocyte-associated and tocilizumab-responding cytokine storm., Chuang Guo, Bin Li, Huan Ma, Xiaofang Wang, Pengfei Cai, Qiaoni Yu, Lin Zhu, Liying Jin, Chen Jiang, Jingwen Fang, Qian Liu, Dandan Zong, Wen Zhang, Yichen Lu, Kun Li, Xuyuan Gao, Binqing Fu, Lianxin Liu, Xiaoling Ma, Jianping Weng, Haiming Wei, Tengchuan Jin, Jun Lin, Kun Qu, 2020

单细胞组学生物信息学免疫细胞亚群自身免疫病致病机制环状Dna 临床诊断治疗靶点数据分析免疫学

王洁 - 中南大学

霍治 - 中南大学

王芙艳 - 中南大学

Area of Focus
免疫学 | 感染 | 免疫 | 衣原体 | 致病机制 | 疫苗 | 流感 | 研究 | 病毒学 | 微生物学

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