Professor | Liang Chen | Asia Growth Partners

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Name	Liang Chen
Contact Information	anqingcl@ustc.edu.cn
Language ability	Chinese, English
Province	Anhui

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Name

Liang Chen

Contact Information

anqingcl@ustc.edu.cn

Language ability

Chinese, English

Province

Anhui

University/Lab Affiliation and Title	University of Science and Technology of China
Faculty	Basic Medical Sciences
Academic Background & Achievements	PhD: University of Science and Technology of China, Biochemistry and Molecular Biology Outstanding Doctoral Dissertation Award from the Chinese Academy of Sciences Reserve candidate for academic and technical leaders in Anhui Province First Prize in Natural Science of Anhui Province (2/4)
Work Experience	Postdoctoral Researcher - School of Basic Medicine, University of Science and Technology of China Special Researcher - School of Basic Medicine, University of Science and Technology of China April 2023 - Present: Dual-appointed at the School of Life Sciences and Medicine and the Cardiovascular Research Institute, First Affiliated Hospital, University of Science and Technology of China
Awards	Outstanding Doctoral Dissertation Award from the Chinese Academy of Sciences First Prize in Natural Science of Anhui Province (2/4) First Outstanding Paper Research Award, School of Life Sciences, University of Science and Technology of China

University/Lab Affiliation and Title

University of Science and Technology of China

Faculty

Basic Medical Sciences

Academic Background & Achievements

PhD: University of Science and Technology of China, Biochemistry and Molecular Biology
Outstanding Doctoral Dissertation Award from the Chinese Academy of Sciences
Reserve candidate for academic and technical leaders in Anhui Province
First Prize in Natural Science of Anhui Province (2/4)

Work Experience

Postdoctoral Researcher - School of Basic Medicine, University of Science and Technology of China
Special Researcher - School of Basic Medicine, University of Science and Technology of China
April 2023 - Present: Dual-appointed at the School of Life Sciences and Medicine and the Cardiovascular Research Institute, First Affiliated Hospital, University of Science and Technology of China

Awards

Outstanding Doctoral Dissertation Award from the Chinese Academy of Sciences
First Prize in Natural Science of Anhui Province (2/4)
First Outstanding Paper Research Award, School of Life Sciences, University of Science and Technology of China

Areas of Focus	Functions and mechanisms of non-coding RNA in tumors and cardiovascular diseases Molecular mechanisms of non-coding RNA in tumor metastasis and drug resistance regulation Non-coding RNA and external stress regulation Physiological and pathological associations of circular RNA generation and nuclear export regulation
Publications	Systematic identification and characterization of Exon-intron circRNAs, Yinchun Zhong, Yan Yang, Xiaolin Wang, Bingbing Ren, Xueren Wang, Ge Shan, Liang Chen, 2024 Ascites exosomal lncRNA PLADE enhances platinum sensitivity by inducing R-loops in ovarian cancer, Hanyuan Liu, Sisi Deng, Xuelin Yao, Yi Liu, Lili Qian, Yingying Wang, Tianjiao Zhang, Ge Shan, Liang Chen, Ying Zhou, 2024 LncRNA RGMB-AS1 inhibits HMOX1 ubiquitination and NAA10 activation to induce ferroptosis in non-small cell lung cancer, Gui-Bin Gao, Liang Chen, Jia-Feng Pan, Tao Lei, Xin Cai, Zhexue Hao, Qi Wang, Ge Shan, Jin Li, 2024 HNRNPD regulates the biogenesis of circRNAs and the ratio of mRNAs to circRNAs for a set of genes, Shuhui Chang, Yucong Wang, Xiaolin Wang, Hanyuan Liu, Tao Zhang, Yangge Zheng, Xueren Wang, Ge Shan, Liang Chen, 2024 Expanding roles of circRNAs in cardiovascular disease, Xu Liu, Xuelin Yao, Liang Chen, 2024 Circular RNA EIF3I promotes papillary thyroid cancer progression by interacting with AUF1 to increase Cyclin D1 production, Xuelin Yao, Hanyuan Liu, Zhen Wang, Fangting Lu, Wenying Chen, Qing Feng, Yahu Miao, Jie Zhang, Yanlei Wang, Ye Chen, Liping Xue, Yehai Liu, Liang Chen, Qiu Zhang, 2023 Circular RNA ARHGAP5 inhibits cisplatin resistance in cervical squamous cell carcinoma by interacting with AUF1, Sisi Deng, Lili Qian, Luwen Liu, Hanyuan Liu, Zhihao Xu, Yujie Liu, Yingying Wang, Liang Chen, Ying Zhou, 2023 Exportin 4 depletion leads to nuclear accumulation of a subset of circular RNAs, Liang Chen, Yucong Wang, Jiamei Lin, Zhenxing Song, Qinwei Wang, Wenfang Zhao, Yan Wang, Xiaoyu Xiu, Yuqi Deng, Xiuzhi Li, Qiqi Li, Xiaolin Wang, Jingxin Li, Xu Liu, Kunpeng Liu, Jincong Zhou, Kuan Li, Yuchan Liu, Shanhui Liao, Qin Deng, Chao Xu, Qianwen Sun, Shengzhou Wu, Kaiming Zhang, Min-Xin Guan, Tianhua Zhou, Fei Sun, Xiujun Cai, Chuan Huang, Ge Shan, 2022 Circular RNAs in physiology and non-immunological diseases, Liang Chen, Chuan Huang, Ge Shan, 2022 Comprehensive identification of RNA transcripts and construction of RNA network in chronic obstructive pulmonary disease, Pengcheng Liu, Yucong Wang, Ningning Zhang, Xiaomin Zhao, Renming Li, Yu Wang, Chen Chen, Dandan Wang, Xiaoming Zhang, Liang Chen, Dahai Zhao, 2022 CircRNA in cancer: Fundamental mechanism and clinical potential, Liang Chen, Ge Shan, 2021 lncRNA PART1 and MIR17HG as δNp63 alpha direct targets regulate tumor progression of cervical squamous cell carcinoma, Hanyuan Liu, Chenchen Zhu, Zhihao Xu, Juan Wang, Lili Qian, Qingqing Zhou, Zhen Shen, Weidong Zhao, Weihua Xiao, Liang Chen, Ying Zhou, 2020 ΔNp63α exerts antitumor functions in cervical squamous cell carcinoma, Ying Zhou, Hanyuan Liu, Juan Wang, Xiaolin Wang, Lili Qian, Fei Xu, Weiguo Song, Dabao Wu, Zhen Shen, Dingqing Feng, Bin Ling, Weihua Xiao, Ge Shan, Liang Chen, 2019 Analyses of a panel of transcripts identified from a small sample size and construction of RNA networks in hepatocellular carcinoma, Zhiyong Sheng, Xiaolin Wang, Geliang Xu, Ge Shan, Liang Chen, 2019 Targetable long non-coding RNAs in cancer treatments, Liang Chen, Emmanuel Enoch Dzakah, Ge Shan, 2018 Comparing two approaches of miR-34a target identification, biotinylated-miRNA pulldown vs miRNA overexpression, Hassaan M Awan, Abdullah Shah, Farooq Rashid, Shuai Wei, Liang Chen, Ge Shan, 2018 The DEAD-Box RNA Helicase DDX3 Interacts with m(6)A RNA Demethylase ALKBH5, Abdullah Shah, Farooq Rashid, Hassaan M Awan, Shanshan Hu, Xiaolin Wang, Liang Chen, Ge Shan, 2017 The isolation of an RNA aptamer targeting to p53 protein with single amino acid mutation, Liang Chen, Farooq Rashid, Abdullah Shah, Hassaan M Awan, Mingming Wu, An Liu, Jun Wang, Tao Zhu, Zhaofeng Luo, Ge Shan, 2015 Circular RNAs remain peculiarly unclear in biogenesis and function, Liang Chen, Ge Shan, 2015 Circular RNAs in Eukaryotic Cells, Liang Chen, Chuan Huang, Xiaolin Wang, Ge Shan, 2015

Areas of Focus

Functions and mechanisms of non-coding RNA in tumors and cardiovascular diseases
Molecular mechanisms of non-coding RNA in tumor metastasis and drug resistance regulation
Non-coding RNA and external stress regulation
Physiological and pathological associations of circular RNA generation and nuclear export regulation

Publications

Systematic identification and characterization of Exon-intron circRNAs, Yinchun Zhong, Yan Yang, Xiaolin Wang, Bingbing Ren, Xueren Wang, Ge Shan, Liang Chen, 2024
Ascites exosomal lncRNA PLADE enhances platinum sensitivity by inducing R-loops in ovarian cancer, Hanyuan Liu, Sisi Deng, Xuelin Yao, Yi Liu, Lili Qian, Yingying Wang, Tianjiao Zhang, Ge Shan, Liang Chen, Ying Zhou, 2024
LncRNA RGMB-AS1 inhibits HMOX1 ubiquitination and NAA10 activation to induce ferroptosis in non-small cell lung cancer, Gui-Bin Gao, Liang Chen, Jia-Feng Pan, Tao Lei, Xin Cai, Zhexue Hao, Qi Wang, Ge Shan, Jin Li, 2024
HNRNPD regulates the biogenesis of circRNAs and the ratio of mRNAs to circRNAs for a set of genes, Shuhui Chang, Yucong Wang, Xiaolin Wang, Hanyuan Liu, Tao Zhang, Yangge Zheng, Xueren Wang, Ge Shan, Liang Chen, 2024
Expanding roles of circRNAs in cardiovascular disease, Xu Liu, Xuelin Yao, Liang Chen, 2024
Circular RNA EIF3I promotes papillary thyroid cancer progression by interacting with AUF1 to increase Cyclin D1 production, Xuelin Yao, Hanyuan Liu, Zhen Wang, Fangting Lu, Wenying Chen, Qing Feng, Yahu Miao, Jie Zhang, Yanlei Wang, Ye Chen, Liping Xue, Yehai Liu, Liang Chen, Qiu Zhang, 2023
Circular RNA ARHGAP5 inhibits cisplatin resistance in cervical squamous cell carcinoma by interacting with AUF1, Sisi Deng, Lili Qian, Luwen Liu, Hanyuan Liu, Zhihao Xu, Yujie Liu, Yingying Wang, Liang Chen, Ying Zhou, 2023
Exportin 4 depletion leads to nuclear accumulation of a subset of circular RNAs, Liang Chen, Yucong Wang, Jiamei Lin, Zhenxing Song, Qinwei Wang, Wenfang Zhao, Yan Wang, Xiaoyu Xiu, Yuqi Deng, Xiuzhi Li, Qiqi Li, Xiaolin Wang, Jingxin Li, Xu Liu, Kunpeng Liu, Jincong Zhou, Kuan Li, Yuchan Liu, Shanhui Liao, Qin Deng, Chao Xu, Qianwen Sun, Shengzhou Wu, Kaiming Zhang, Min-Xin Guan, Tianhua Zhou, Fei Sun, Xiujun Cai, Chuan Huang, Ge Shan, 2022
Circular RNAs in physiology and non-immunological diseases, Liang Chen, Chuan Huang, Ge Shan, 2022
Comprehensive identification of RNA transcripts and construction of RNA network in chronic obstructive pulmonary disease, Pengcheng Liu, Yucong Wang, Ningning Zhang, Xiaomin Zhao, Renming Li, Yu Wang, Chen Chen, Dandan Wang, Xiaoming Zhang, Liang Chen, Dahai Zhao, 2022
CircRNA in cancer: Fundamental mechanism and clinical potential, Liang Chen, Ge Shan, 2021
lncRNA PART1 and MIR17HG as δNp63 alpha direct targets regulate tumor progression of cervical squamous cell carcinoma, Hanyuan Liu, Chenchen Zhu, Zhihao Xu, Juan Wang, Lili Qian, Qingqing Zhou, Zhen Shen, Weidong Zhao, Weihua Xiao, Liang Chen, Ying Zhou, 2020
ΔNp63α exerts antitumor functions in cervical squamous cell carcinoma, Ying Zhou, Hanyuan Liu, Juan Wang, Xiaolin Wang, Lili Qian, Fei Xu, Weiguo Song, Dabao Wu, Zhen Shen, Dingqing Feng, Bin Ling, Weihua Xiao, Ge Shan, Liang Chen, 2019
Analyses of a panel of transcripts identified from a small sample size and construction of RNA networks in hepatocellular carcinoma, Zhiyong Sheng, Xiaolin Wang, Geliang Xu, Ge Shan, Liang Chen, 2019
Targetable long non-coding RNAs in cancer treatments, Liang Chen, Emmanuel Enoch Dzakah, Ge Shan, 2018
Comparing two approaches of miR-34a target identification, biotinylated-miRNA pulldown vs miRNA overexpression, Hassaan M Awan, Abdullah Shah, Farooq Rashid, Shuai Wei, Liang Chen, Ge Shan, 2018
The DEAD-Box RNA Helicase DDX3 Interacts with m(6)A RNA Demethylase ALKBH5, Abdullah Shah, Farooq Rashid, Hassaan M Awan, Shanshan Hu, Xiaolin Wang, Liang Chen, Ge Shan, 2017
The isolation of an RNA aptamer targeting to p53 protein with single amino acid mutation, Liang Chen, Farooq Rashid, Abdullah Shah, Hassaan M Awan, Mingming Wu, An Liu, Jun Wang, Tao Zhu, Zhaofeng Luo, Ge Shan, 2015
Circular RNAs remain peculiarly unclear in biogenesis and function, Liang Chen, Ge Shan, 2015
Circular RNAs in Eukaryotic Cells, Liang Chen, Chuan Huang, Xiaolin Wang, Ge Shan, 2015

Non-Coding Rna Tumors Cardiovascular Diseases Mechanisms Metastasis Drug Resistance External Stress Circular Rna Nuclear Export Physiological Associations

Dongyu Zhao - Peking University

Dan Meng - Fudan University

Yuanyuan Wei - Fudan University

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