Professor | Hongbin He | Asia Growth Partners

Upload Avatar (500 x 500)

Name

Hongbin He

Contact Information

hhb123@ustc.edu.cn

Language ability

Chinese, English

Province

Anhui

University/Lab Affiliation and Title	University of Science and Technology of China
Faculty	Basic Medical Sciences
Academic Background & Achievements	2013 - Bachelor's degree in Agronomy: Jilin University 2018 - Doctorate in Science: University of Science and Technology of China 2018 - Excellent Doctoral Dissertation: University of Science and Technology of China 2018 - President's Award for Excellence: Chinese Academy of Sciences
Work Experience	2018-2021 - Postdoctoral Research: University of Science and Technology of China 2021-Present - Special Associate Researcher: University of Science and Technology of China
Awards	2018: Excellent Doctoral Dissertation, University of Science and Technology of China 2018: President's Award for Excellence, Chinese Academy of Sciences

University/Lab Affiliation and Title

University of Science and Technology of China

Faculty

Basic Medical Sciences

Academic Background & Achievements

2013 - Bachelor's degree in Agronomy: Jilin University
2018 - Doctorate in Science: University of Science and Technology of China
2018 - Excellent Doctoral Dissertation: University of Science and Technology of China
2018 - President's Award for Excellence: Chinese Academy of Sciences

Work Experience

2018-2021 - Postdoctoral Research: University of Science and Technology of China
2021-Present - Special Associate Researcher: University of Science and Technology of China

Awards

2018: Excellent Doctoral Dissertation, University of Science and Technology of China
2018: President's Award for Excellence, Chinese Academy of Sciences

Areas of Focus	Exploration of NLRP3 inflammasome activation mechanisms Development of therapeutic strategies targeting NLRP3-related diseases
Publications	Oridonin is a covalent NLRP3 inhibitor with strong anti-inflammasome activity, He H, Jiang H, Chen Y, Ye J, Wang A, Wang C, Liu Q, Liang G, Deng X#, Jiang W#, Zhou R#, 2018 Identification of a selective and direct NLRP3 inhibitor to treat inflammatory disorders, Jiang H, He H, Chen Y, Huang W, Cheng J, Ye J, Wang A, Tao J, Wang C, Liu Q, Jin T, Jiang W#, Deng X#, Zhou R#, 2017 RRx-001 ameliorates inflammatory diseases by acting as a potent covalent NLRP3 inhibitor, Chen Y, He H, Lin B, Chen Y, Deng X, Jiang W#, Zhou R#, 2021 Discovery and optimization of 4-oxo-2-thioxo-thiazolidinones as NOD-like receptor (NLR) family, pyrin domain-containing protein 3 (NLRP3) inhibitors, Chen Y, He H, Jiang H*, Li L, Hu Z, Huang H, Xu Q, Zhou R#, Deng X#, 2020

Areas of Focus

Exploration of NLRP3 inflammasome activation mechanisms
Development of therapeutic strategies targeting NLRP3-related diseases

Publications

Oridonin is a covalent NLRP3 inhibitor with strong anti-inflammasome activity, He H*, Jiang H*, Chen Y*, Ye J, Wang A, Wang C, Liu Q, Liang G, Deng X#, Jiang W#, Zhou R#, 2018
Identification of a selective and direct NLRP3 inhibitor to treat inflammatory disorders, Jiang H*, He H*, Chen Y*, Huang W, Cheng J, Ye J, Wang A, Tao J, Wang C, Liu Q, Jin T, Jiang W#, Deng X#, Zhou R#, 2017
RRx-001 ameliorates inflammatory diseases by acting as a potent covalent NLRP3 inhibitor, Chen Y*, He H*, Lin B, Chen Y, Deng X, Jiang W#, Zhou R#, 2021
Discovery and optimization of 4-oxo-2-thioxo-thiazolidinones as NOD-like receptor (NLR) family, pyrin domain-containing protein 3 (NLRP3) inhibitors, Chen Y*, He H*, Jiang H*, Li L, Hu Z, Huang H, Xu Q, Zhou R#, Deng X#, 2020

Nlrp3 Inflammasome Activation Mechanisms Therapeutic Strategies Diseases Targeting Research Development

Yang Liu - Fudan University

Qing Lu - Fudan University

Qi-Qun Tang - Fudan University

View All

Personal Information