Professor | Zhigang Tian | Asia Growth Partners

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Name	Zhigang Tian
Contact Information	tzg@ustc.edu.cn
Language ability	Chinese, English
Province	Anhui

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Name

Zhigang Tian

Contact Information

tzg@ustc.edu.cn

Language ability

Chinese, English

Province

Anhui

University/Lab Affiliation and Title	University of Science and Technology of China
Faculty	Basic Medical Sciences
Academic Background & Achievements	National Outstanding Youth Science Fund Recipient Leader of the National Natural Science Foundation of China Innovation Research Group 28 National Invention Patents Second Prize of National Natural Science Award Second Prize of National Science and Technology Progress Award Ho Leung Ho Lee Foundation Science and Technology Progress Award
Work Experience	Current - University of Science and Technology of China - Professor, Dean of the School of Basic Medicine, Director of the Institute of Immunology Past - University of Science and Technology of China - Director of the Medical Center, Dean of the School of Life Sciences
Awards	Second Prize of National Natural Science Award Second Prize of National Science and Technology Progress Award Ho Leung Ho Lee Foundation Science and Technology Progress Award

University/Lab Affiliation and Title

University of Science and Technology of China

Faculty

Basic Medical Sciences

Academic Background & Achievements

National Outstanding Youth Science Fund Recipient
Leader of the National Natural Science Foundation of China Innovation Research Group
28 National Invention Patents
Second Prize of National Natural Science Award
Second Prize of National Science and Technology Progress Award
Ho Leung Ho Lee Foundation Science and Technology Progress Award

Work Experience

Current - University of Science and Technology of China - Professor, Dean of the School of Basic Medicine, Director of the Institute of Immunology
Past - University of Science and Technology of China - Director of the Medical Center, Dean of the School of Life Sciences

Awards

Second Prize of National Natural Science Award
Second Prize of National Science and Technology Progress Award
Ho Leung Ho Lee Foundation Science and Technology Progress Award

Areas of Focus	Discovery of new NK cell subgroups Liver NK cells Development of new immunotherapies and products based on NK cells
Publications	Liver type 1 innate lymphoid cells develop locally via an interferon-γ-dependent loop., Bai L, Vienne M, Tang L, Kerdiles Y, Etiennot M, Escalière B, Galluso J, Wei H, Sun R, Vivier E, Peng H, Tian Z., 2021 PBX1 expression in uterine natural killer cells drives fetal growth., Zhou Y, Fu B, Xu X, Zhang J, Tong X, Wang Y, Dong Z, Zhang X, Shen N, Zhai Y, Kong X, Sun R, Tian Z, Wei H., 2020 Liver-resident NK cells control antiviral activity of hepatic T cells via PD-1/PD-L1 axis., Zhou J, Peng H, Li K, Qu K, Wang B, Wu Y, Ye L, Dong Z, Wei H, Sun R, Tian Z., 2019 Mitochondrial fragmentation limits NK cell-based tumor immunosurveillance., Zheng X, Qian Y, Fu B, Jiao D, Jiang Y, Chen P, Shen Y, Zhang H, Sun R, Tian Z, Wei H., 2019 Blockade of the checkpoint receptor TIGIT prevents NK cell exhaustion and elicits potent anti-tumor immunity., Zhang Q, Bi J, Zheng X, Chen Y, Wang H, Wu W, Wang Z, Wu Q, Peng H, Wei H, Sun R, Tian Z., 2018 Dysfunction of Natural Killer Cells by FBP1-Induced Inhibition of Glycolysis during Lung Cancer Progression., Cong J, Wang X, Zheng X, Wang D, Fu B, Sun R, Tian Z, Wei H., 2018 Natural Killer Cells Promote Fetal Development through the Secretion of Growth-Promoting Factors., Fu B, Zhou Y, Ni X, Tong X, Xu X, Dong Z, Sun R, Tian Z, Wei H., 2017 The Self-Specific Activation Receptor SLAM Family Is Critical for NK Cell Education., Chen S, Yang M, Du J, Li D, Li Z, Cai C, Ma Y, Zhang L, Tian Z, Dong Z., 2016 Dopamine controls systemic inflammation through inhibition of NLRP3 inflammasome., Yan Y, Jiang W, Liu L, Wang X, Ding C, Tian Z, Zhou R., 2015 RNA viruses promote activation of the NLRP3 inflammasome through a RIP1-RIP3-DRP1 signaling pathway., Wang X, Jiang W, Yan Y, Gong T, Han J, Tian Z, Zhou R., 2014 ω-3 fatty acids prevent inflammation and metabolic disorder through inhibition of NLRP3 inflammasome activation., Yan Y, Jang W, Spinetti T, Tardivel A, Castillo R, Guarda G, Tian Z, Tschopp J, Zhou RB., 2013

Areas of Focus

Discovery of new NK cell subgroups
Liver NK cells
Development of new immunotherapies and products based on NK cells

Publications

Liver type 1 innate lymphoid cells develop locally via an interferon-γ-dependent loop., Bai L, Vienne M, Tang L, Kerdiles Y, Etiennot M, Escalière B, Galluso J, Wei H, Sun R, Vivier E, Peng H, Tian Z., 2021
PBX1 expression in uterine natural killer cells drives fetal growth., Zhou Y, Fu B, Xu X, Zhang J, Tong X, Wang Y, Dong Z, Zhang X, Shen N, Zhai Y, Kong X, Sun R, Tian Z, Wei H., 2020
Liver-resident NK cells control antiviral activity of hepatic T cells via PD-1/PD-L1 axis., Zhou J, Peng H, Li K, Qu K, Wang B, Wu Y, Ye L, Dong Z, Wei H, Sun R, Tian Z., 2019
Mitochondrial fragmentation limits NK cell-based tumor immunosurveillance., Zheng X, Qian Y, Fu B, Jiao D, Jiang Y, Chen P, Shen Y, Zhang H, Sun R, Tian Z, Wei H., 2019
Blockade of the checkpoint receptor TIGIT prevents NK cell exhaustion and elicits potent anti-tumor immunity., Zhang Q, Bi J, Zheng X, Chen Y, Wang H, Wu W, Wang Z, Wu Q, Peng H, Wei H, Sun R, Tian Z., 2018
Dysfunction of Natural Killer Cells by FBP1-Induced Inhibition of Glycolysis during Lung Cancer Progression., Cong J, Wang X, Zheng X, Wang D, Fu B, Sun R, Tian Z, Wei H., 2018
Natural Killer Cells Promote Fetal Development through the Secretion of Growth-Promoting Factors., Fu B, Zhou Y, Ni X, Tong X, Xu X, Dong Z, Sun R, Tian Z, Wei H., 2017
The Self-Specific Activation Receptor SLAM Family Is Critical for NK Cell Education., Chen S, Yang M, Du J, Li D, Li Z, Cai C, Ma Y, Zhang L, Tian Z, Dong Z., 2016
Dopamine controls systemic inflammation through inhibition of NLRP3 inflammasome., Yan Y, Jiang W, Liu L, Wang X, Ding C, Tian Z, Zhou R., 2015
RNA viruses promote activation of the NLRP3 inflammasome through a RIP1-RIP3-DRP1 signaling pathway., Wang X, Jiang W, Yan Y, Gong T, Han J, Tian Z, Zhou R., 2014
ω-3 fatty acids prevent inflammation and metabolic disorder through inhibition of NLRP3 inflammasome activation., Yan Y, Jang W, Spinetti T, Tardivel A, Castillo R, Guarda G, Tian Z, Tschopp J, Zhou RB., 2013

Nk Cells Immunotherapy Liver Subgroups Discovery Development Products Immune System Chronic Diseases Natural Killer Cells

Zhigang Tian - University of Science and Technology of China

Zhigang Tian - University of Science and Technology of China

Cheng-Ran Xu - Peking University

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