Professor | Zhigang Tian | Asia Growth Partners

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Name	Zhigang Tian
Contact Information	tzg@ustc.edu.cn
Language ability	Chinese, English
Province	Anhui

Upload Avatar (500 x 500)

Name

Zhigang Tian

Contact Information

tzg@ustc.edu.cn

Language ability

Chinese, English

Province

Anhui

University/Lab Affiliation and Title	University of Science and Technology of China
Faculty	Basic Medical Sciences
Awards	National Natural Science Second Prize: Detail not mentioned National Science and Technology Progress Second Prize: Detail not mentioned Ho Leung Ho Lee Science and Technology Progress Award: Detail not mentioned

University/Lab Affiliation and Title

University of Science and Technology of China

Faculty

Basic Medical Sciences

Awards

National Natural Science Second Prize: Detail not mentioned
National Science and Technology Progress Second Prize: Detail not mentioned
Ho Leung Ho Lee Science and Technology Progress Award: Detail not mentioned

Areas of Focus	Discovery of new NK cell subsets Liver NK cells Novel immunotherapy and product development based on NK cells
Publications	Tumors evade immune cytotoxicity by altering the surface topology of NK cells, Zheng X, Hou Z, Qian Y, Zhang Y, Cui Q, Wang X, Shen Y, Liu Z, Zhou Y, Fu B, Sun R, Tian Z, Huang G, Wei H, 2023 Liver type 1 innate lymphoid cells develop locally via an interferon-γ-dependent loop, Bai L, Vienne M, Tang L, Kerdiles Y, Etiennot M, Escalière B, Galluso J, Wei H, Sun R, Vivier E, Peng H, Tian Z, 2021 PBX1 expression in uterine natural killer cells drives fetal growth, Zhou Y, Fu B, Xu X, Zhang J, Tong X, Wang Y, Dong Z, Zhang X, Shen N, Zhai Y, Kong X, Sun R, Tian Z, Wei H, 2020 Liver-resident NK cells control antiviral activity of hepatic T cells via PD-1/PD-L1 axis, Zhou J, Peng H, Li K, Qu K, Wang B, Wu Y, Ye L, Dong Z, Wei H, Sun R, Tian Z, 2019 Mitochondrial fragmentation limits NK cell-based tumor immunosurveillance, Zheng X, Qian Y, Fu B, Jiao D, Jiang Y, Chen P, Shen Y, Zhang H, Sun R, Tian Z, Wei H, 2019 Blockade of the checkpoint receptor TIGIT prevents NK cell exhaustion and elicits potent anti-tumor immunity, Zhang Q, Bi J, Zheng X, Chen Y, Wang H, Wu W, Wang Z, Wu Q, Peng H, Wei H, Sun R, Tian Z, 2018 Dysfunction of Natural Killer Cells by FBP1-Induced Inhibition of Glycolysis during Lung Cancer Progression, Cong J, Wang X, Zheng X, Wang D, Fu B, Sun R, Tian Z, Wei H, 2018 Natural Killer Cells Promote Fetal Development through the Secretion of Growth-Promoting Factors, Fu B, Zhou Y, Ni X, Tong X, Xu X, Dong Z, Sun R, Tian Z, Wei H, 2017 The Self-Specific Activation Receptor SLAM Family Is Critical for NK Cell Education, Chen S, Yang M, Du J, Li D, Li Z, Cai C, Ma Y, Zhang L, Tian Z, Dong Z, 2016 Dopamine controls systemic inflammation through inhibition of NLRP3 inflammasome, Yan Y, Jiang W, Liu L, Wang X, Ding C, Tian Z, Zhou R, 2015 RNA viruses promote activation of the NLRP3 inflammasome through a RIP1-RIP3-DRP1 signaling pathway, Wang X, Jiang W, Yan Y, Gong T, Han J, Tian Z, Zhou R, 2014 ω-3 fatty acids prevent inflammation and metabolic disorder through inhibition of NLRP3 inflammasome activation, Yan Y, Jang W, Spinetti T, Tardivel A, Castillo R, Guarda G, Tian Z, Tschopp J, Zhou RB, 2013 Blocking the Natural Killer (NK) Cell Inhibitory Receptor NKG2A Increases Activity of Human NK Cells and Clears HBV Infection in Mice, Li F, Wei H, Wei H, Gao Y, Xu L, Yin W, Sun R, Tian Z, 2013 Liver type I regulatory T cells suppress germinal center formation in HBV-tolerant mice, Xu L, Yin WW, Wei HM, Sun R, Tian Z, 2013

Areas of Focus

Discovery of new NK cell subsets
Liver NK cells
Novel immunotherapy and product development based on NK cells

Publications

Tumors evade immune cytotoxicity by altering the surface topology of NK cells, Zheng X, Hou Z, Qian Y, Zhang Y, Cui Q, Wang X, Shen Y, Liu Z, Zhou Y, Fu B, Sun R, Tian Z, Huang G, Wei H, 2023
Liver type 1 innate lymphoid cells develop locally via an interferon-γ-dependent loop, Bai L, Vienne M, Tang L, Kerdiles Y, Etiennot M, Escalière B, Galluso J, Wei H, Sun R, Vivier E, Peng H, Tian Z, 2021
PBX1 expression in uterine natural killer cells drives fetal growth, Zhou Y, Fu B, Xu X, Zhang J, Tong X, Wang Y, Dong Z, Zhang X, Shen N, Zhai Y, Kong X, Sun R, Tian Z, Wei H, 2020
Liver-resident NK cells control antiviral activity of hepatic T cells via PD-1/PD-L1 axis, Zhou J, Peng H, Li K, Qu K, Wang B, Wu Y, Ye L, Dong Z, Wei H, Sun R, Tian Z, 2019
Mitochondrial fragmentation limits NK cell-based tumor immunosurveillance, Zheng X, Qian Y, Fu B, Jiao D, Jiang Y, Chen P, Shen Y, Zhang H, Sun R, Tian Z, Wei H, 2019
Blockade of the checkpoint receptor TIGIT prevents NK cell exhaustion and elicits potent anti-tumor immunity, Zhang Q, Bi J, Zheng X, Chen Y, Wang H, Wu W, Wang Z, Wu Q, Peng H, Wei H, Sun R, Tian Z, 2018
Dysfunction of Natural Killer Cells by FBP1-Induced Inhibition of Glycolysis during Lung Cancer Progression, Cong J, Wang X, Zheng X, Wang D, Fu B, Sun R, Tian Z, Wei H, 2018
Natural Killer Cells Promote Fetal Development through the Secretion of Growth-Promoting Factors, Fu B, Zhou Y, Ni X, Tong X, Xu X, Dong Z, Sun R, Tian Z, Wei H, 2017
The Self-Specific Activation Receptor SLAM Family Is Critical for NK Cell Education, Chen S, Yang M, Du J, Li D, Li Z, Cai C, Ma Y, Zhang L, Tian Z, Dong Z, 2016
Dopamine controls systemic inflammation through inhibition of NLRP3 inflammasome, Yan Y, Jiang W, Liu L, Wang X, Ding C, Tian Z, Zhou R, 2015
RNA viruses promote activation of the NLRP3 inflammasome through a RIP1-RIP3-DRP1 signaling pathway, Wang X, Jiang W, Yan Y, Gong T, Han J, Tian Z, Zhou R, 2014
ω-3 fatty acids prevent inflammation and metabolic disorder through inhibition of NLRP3 inflammasome activation, Yan Y, Jang W, Spinetti T, Tardivel A, Castillo R, Guarda G, Tian Z, Tschopp J, Zhou RB, 2013
Blocking the Natural Killer (NK) Cell Inhibitory Receptor NKG2A Increases Activity of Human NK Cells and Clears HBV Infection in Mice, Li F, Wei H, Wei H, Gao Y, Xu L, Yin W, Sun R, Tian Z, 2013
Liver type I regulatory T cells suppress germinal center formation in HBV-tolerant mice, Xu L, Yin WW, Wei HM, Sun R, Tian Z, 2013

Nk Cells Subsets Immunotherapy Liver Product Development Immune System Cancer Chronic Diseases Patents Research

Yang Li - Peking University

Xiaowei Zhang - Peking University

Yanhui Yin - Peking University

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