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Shu Zhu
Basic Medical Sciences
University of Science and Technology of China
Anhui
Language: Chinese, English
Gut Microbiota
Immune Recognition
Immune Regulation
Microbial Therapy
Immunotherapy
Nlrp6
Gsdmd
Intestinal Health
Microbial Metabolites
Immune Homeostasis
Areas of Focus
- Immune recognition and regulation of gut microbiota
- New therapies in microbiology and immunology
Work Experience
- 2017-present - University of Science and Technology of China - Professor and Doctoral Supervisor
Academic Background & Achievements
- 2002-2006 Bachelor: University of Science and Technology of China
- 2006-2012 PhD in Cell Biology: Shanghai Institute of Health Sciences
- Postdoctoral Research: Yale University School of Medicine, Department of Immunology
Publications
- Bile acids modified by the microbiota suppress gut anti-tumor immune responses., Cong J, Liu P, Han Z, Ying W, Li C, Yang J, Song X, Dai L, Sun L, Kasper D, Pan W, Zhu S., 2024
- DHX9 maintains epithelial homeostasis by restraining R-loop-mediated genomic instability in intestinal stem cells., Ren X, Liu Q, Zhou P, Zhou T, Wang D, Mei Q, Flavell RA, Liu Z, Li M, Pan W, Zhu S., 2024
- Amino-acid formula induces microbiota dysbiosis and contributes to depressive-like behavior., Hu J, He K, Yang Y, Huang C, Dou Y, Wang H, Zhang G, Wang J, Niu C, Bi G, Zhang L, Zhu S., 2024
- A mouse model to distinguish NLRP6-mediated inflammasome-dependent and independent functions., Li R, Zan Y, Wang D, Chen X, Wang A, Tan H, Zhang G, Ding S, Shen C, Wu H, Zhu S., 2024
- Gut microbial metabolite facilitates colorectal cancer development via ferroptosis inhibition., Cui W, Guo M, Liu D, Zhang Y, Cong J, Han Z, Yang Y, Liu J, Liang C, Shi S, Xiao P, Yang C, Huang H, Fu X, Xu Y, Du L, Yin C, Zhang Y, Sun J, Chai R, Gu W, Zhu S, Chu B., 2024
- Gasdermin D licenses MHCII induction to maintain food tolerance in small intestine., He K, Wan T, Wang D, Hu J, Zhou T, Tao W, Wei Z, Lu Q, Zhou R, Tian Z, Flavell R, Zhu S., 2023
- Microbial sensing in the intestine., Wan T, Wang Y, He K, Zhu S., 2023
- A lncRNA from an inflammatory bowel disease risk locus maintains intestinal host-commensal homeostasis., Ma H, Hu T, Tao W, Tong J, Han Z, Herndler-Brandstetter D, Wei Z, Xu X, Zhang K, Liu R, Zhou T, Liu Q, Cho J, Li HB, Huang H, Flavell R, Zhu S., 2023
- Nucleic DHX9 Cooperates with STAT1 to Transcribe Interferon-Stimulated Genes., Ren X, Wang D, Zhang G, Zhou T, Wei Z, Yang Y, Zheng Y, Lei X, Tao W, Wang A, Li M, Flavell R, Zhu S., 2023
- m6A mRNA modification potentiates Th17 functions to inflame autoimmunity., Wang X, Chen C, Sun H, Mao K, Yao J, Zhang W, Zhan M, Li HB, Zhang Z, Zhu S, Lu L., 2023
Awards
- 2006: Guo Moruo Scholarship
- 2011: CAS President's Excellence Award
- 2011: Johnson & Johnson Asia Outstanding Graduate Thesis Award
- 2012: CAS President's Special Award
- 2012: Wu Rui Scholarship
- 2012: CAS 100 Excellent Doctoral Dissertations
- 2014: Helen-Hay Whitney-HHMI Fellowship
- 2017: Central Organization Department Innovation Talent Program
- 2018: MIT Technology Review 35 Innovators Under 35 China
- 2018: Qiu Shi Outstanding Young Scholar
- 2018: NSFC Excellent Young Scholar
- 2022: Zhongyuan Concord Innovation Breakthrough Award
- 2023: NSFC Distinguished Young Scholar
