Professor | Shu Zhu | Asia Growth Partners

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Name	Shu Zhu
Contact Information	zhushu@ustc.edu.cn
Language ability	Chinese, English
Province	Anhui

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Name

Shu Zhu

Contact Information

zhushu@ustc.edu.cn

Language ability

Chinese, English

Province

Anhui

University/Lab Affiliation and Title	University of Science and Technology of China
Faculty	Basic Medical Sciences
Academic Background & Achievements	2002-2006 Bachelor: University of Science and Technology of China 2006-2012 PhD in Cell Biology: Shanghai Institute of Health Sciences Postdoctoral Research: Yale University School of Medicine, Department of Immunology
Work Experience	2017-present - University of Science and Technology of China - Professor and Doctoral Supervisor
Awards	2006: Guo Moruo Scholarship 2011: CAS President's Excellence Award 2011: Johnson & Johnson Asia Outstanding Graduate Thesis Award 2012: CAS President's Special Award 2012: Wu Rui Scholarship 2012: CAS 100 Excellent Doctoral Dissertations 2014: Helen-Hay Whitney-HHMI Fellowship 2017: Central Organization Department Innovation Talent Program 2018: MIT Technology Review 35 Innovators Under 35 China 2018: Qiu Shi Outstanding Young Scholar 2018: NSFC Excellent Young Scholar 2022: Zhongyuan Concord Innovation Breakthrough Award 2023: NSFC Distinguished Young Scholar

University/Lab Affiliation and Title

University of Science and Technology of China

Faculty

Basic Medical Sciences

Academic Background & Achievements

2002-2006 Bachelor: University of Science and Technology of China
2006-2012 PhD in Cell Biology: Shanghai Institute of Health Sciences
Postdoctoral Research: Yale University School of Medicine, Department of Immunology

Work Experience

2017-present - University of Science and Technology of China - Professor and Doctoral Supervisor

Awards

2006: Guo Moruo Scholarship
2011: CAS President's Excellence Award
2011: Johnson & Johnson Asia Outstanding Graduate Thesis Award
2012: CAS President's Special Award
2012: Wu Rui Scholarship
2012: CAS 100 Excellent Doctoral Dissertations
2014: Helen-Hay Whitney-HHMI Fellowship
2017: Central Organization Department Innovation Talent Program
2018: MIT Technology Review 35 Innovators Under 35 China
2018: Qiu Shi Outstanding Young Scholar
2018: NSFC Excellent Young Scholar
2022: Zhongyuan Concord Innovation Breakthrough Award
2023: NSFC Distinguished Young Scholar

Areas of Focus	Immune recognition and regulation of gut microbiota New therapies in microbiology and immunology
Publications	Bile acids modified by the microbiota suppress gut anti-tumor immune responses., Cong J, Liu P, Han Z, Ying W, Li C, Yang J, Song X, Dai L, Sun L, Kasper D, Pan W, Zhu S., 2024 DHX9 maintains epithelial homeostasis by restraining R-loop-mediated genomic instability in intestinal stem cells., Ren X, Liu Q, Zhou P, Zhou T, Wang D, Mei Q, Flavell RA, Liu Z, Li M, Pan W, Zhu S., 2024 Amino-acid formula induces microbiota dysbiosis and contributes to depressive-like behavior., Hu J, He K, Yang Y, Huang C, Dou Y, Wang H, Zhang G, Wang J, Niu C, Bi G, Zhang L, Zhu S., 2024 A mouse model to distinguish NLRP6-mediated inflammasome-dependent and independent functions., Li R, Zan Y, Wang D, Chen X, Wang A, Tan H, Zhang G, Ding S, Shen C, Wu H, Zhu S., 2024 Gut microbial metabolite facilitates colorectal cancer development via ferroptosis inhibition., Cui W, Guo M, Liu D, Zhang Y, Cong J, Han Z, Yang Y, Liu J, Liang C, Shi S, Xiao P, Yang C, Huang H, Fu X, Xu Y, Du L, Yin C, Zhang Y, Sun J, Chai R, Gu W, Zhu S, Chu B., 2024 Gasdermin D licenses MHCII induction to maintain food tolerance in small intestine., He K, Wan T, Wang D, Hu J, Zhou T, Tao W, Wei Z, Lu Q, Zhou R, Tian Z, Flavell R, Zhu S., 2023 Microbial sensing in the intestine., Wan T, Wang Y, He K, Zhu S., 2023 A lncRNA from an inflammatory bowel disease risk locus maintains intestinal host-commensal homeostasis., Ma H, Hu T, Tao W, Tong J, Han Z, Herndler-Brandstetter D, Wei Z, Xu X, Zhang K, Liu R, Zhou T, Liu Q, Cho J, Li HB, Huang H, Flavell R, Zhu S., 2023 Nucleic DHX9 Cooperates with STAT1 to Transcribe Interferon-Stimulated Genes., Ren X, Wang D, Zhang G, Zhou T, Wei Z, Yang Y, Zheng Y, Lei X, Tao W, Wang A, Li M, Flavell R, Zhu S., 2023 m6A mRNA modification potentiates Th17 functions to inflame autoimmunity., Wang X, Chen C, Sun H, Mao K, Yao J, Zhang W, Zhan M, Li HB, Zhang Z, Zhu S, Lu L., 2023

Areas of Focus

Immune recognition and regulation of gut microbiota
New therapies in microbiology and immunology

Publications

Bile acids modified by the microbiota suppress gut anti-tumor immune responses., Cong J, Liu P, Han Z, Ying W, Li C, Yang J, Song X, Dai L, Sun L, Kasper D, Pan W, Zhu S., 2024
DHX9 maintains epithelial homeostasis by restraining R-loop-mediated genomic instability in intestinal stem cells., Ren X, Liu Q, Zhou P, Zhou T, Wang D, Mei Q, Flavell RA, Liu Z, Li M, Pan W, Zhu S., 2024
Amino-acid formula induces microbiota dysbiosis and contributes to depressive-like behavior., Hu J, He K, Yang Y, Huang C, Dou Y, Wang H, Zhang G, Wang J, Niu C, Bi G, Zhang L, Zhu S., 2024
A mouse model to distinguish NLRP6-mediated inflammasome-dependent and independent functions., Li R, Zan Y, Wang D, Chen X, Wang A, Tan H, Zhang G, Ding S, Shen C, Wu H, Zhu S., 2024
Gut microbial metabolite facilitates colorectal cancer development via ferroptosis inhibition., Cui W, Guo M, Liu D, Zhang Y, Cong J, Han Z, Yang Y, Liu J, Liang C, Shi S, Xiao P, Yang C, Huang H, Fu X, Xu Y, Du L, Yin C, Zhang Y, Sun J, Chai R, Gu W, Zhu S, Chu B., 2024
Gasdermin D licenses MHCII induction to maintain food tolerance in small intestine., He K, Wan T, Wang D, Hu J, Zhou T, Tao W, Wei Z, Lu Q, Zhou R, Tian Z, Flavell R, Zhu S., 2023
Microbial sensing in the intestine., Wan T, Wang Y, He K, Zhu S., 2023
A lncRNA from an inflammatory bowel disease risk locus maintains intestinal host-commensal homeostasis., Ma H, Hu T, Tao W, Tong J, Han Z, Herndler-Brandstetter D, Wei Z, Xu X, Zhang K, Liu R, Zhou T, Liu Q, Cho J, Li HB, Huang H, Flavell R, Zhu S., 2023
Nucleic DHX9 Cooperates with STAT1 to Transcribe Interferon-Stimulated Genes., Ren X, Wang D, Zhang G, Zhou T, Wei Z, Yang Y, Zheng Y, Lei X, Tao W, Wang A, Li M, Flavell R, Zhu S., 2023
m6A mRNA modification potentiates Th17 functions to inflame autoimmunity., Wang X, Chen C, Sun H, Mao K, Yao J, Zhang W, Zhan M, Li HB, Zhang Z, Zhu S, Lu L., 2023

Gut Microbiota Immune Recognition Immune Regulation Microbial Therapy Immunotherapy Nlrp6 Gsdmd Intestinal Health Microbial Metabolites Immune Homeostasis

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