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Bo Liu
Life Science
Xiamen University
Fujian
Language: English, Chinese
Hippo Signaling
Organ Size
Tumorigenesis
Stem Cell
Differentiation
Tissue Regeneration
Innate Immunity
Drosophila
Genetic Screens
Comparative Genomics
Areas of Focus
- Hippo signaling pathway in organ size control, tumorigenesis, stem cell differentiation, tissue regeneration, and innate immunity
Work Experience
- 2013-2016 - Postdoc Fellow: Johns Hopkins University, HHMI
- 2016-2018 - Postdoc Fellow: UT Southwestern Medical Center, HHMI
- 2018-Present - Professor: Xiamen University
Academic Background & Achievements
- 2004 - B.S. in Biological Sciences: Xiamen University
- 2008 - M.S. in Cell Biology: Xiamen University
- 2012 - Ph.D. in Molecular Genetics and Microbiology: University of Florida
- 2018 - Nanqiang Young Top-notch Talent (Class A): Xiamen University
Publications
- Innate immune and proinflammatory signals activate the Hippo pathway via a Tak1-STRIPAK-Tao axis., Yang Y, Zhou H, Huang X, Wu C, Zheng K, Deng J, Zheng Y, Wang J, Chi X, Ma X, Pan H, Shen, R, Pan D, Liu B, 2024
- A dRASSF-STRIPAK-Imd-JAK/STAT axis controls antiviral immune response in Drosophila., Shen R, Zheng K, Zhou Y, Chi X, Pan H, Wu C, Yang Y, Zheng Y, Pan D, Liu B, 2022
- Homeostatic control of Hpo/MST kinase activity through autophosphorylation-dependent recruitment of the STRIPAK PP2A phosphatase complex., Zheng Y, Liu B, Wang L, Lei H, Pulgar Prieto KD, Pan D, 2017
- Toll receptor-mediated Hippo signaling controls innate immunity in Drosophila., Liu B, Zheng Y, Yin F, Yu J, Silverman N, Pan D, 2016
- Identification of Happyhour/MAP4K as alternative Hpo/Mst-like kinases in the Hippo kinase cascade., Zheng Y, Wang W, Liu B, Deng H, Uster E, Pan D, 2015
- P53-mediated rapid induction of apoptosis conveys resistance to viral infection in Drosophila melanogaster., Liu B, Behura SK, Clem RJ, Schneemann A, Becnel J, Severson DW, Zhou L, 2013
- Induction of reaper Ortholog mx in Mosquito midgut cells following baculovirus infection., Bo Liu, James Becnel, Yanping Zhang, Lei Zhou, 2011
- A barrier-only boundary element delimits the formation of facultative heterochromatin in Drosophila melanogaster and vertebrates., Lin N, Li X, Cui K, Chepelev I, Tie F, Liu B, Li G, Harte P, Zhao K, Huang S, Zhou L, 2011
- Regulation of the orphan receptor TR3 nuclear functions by c-Jun N terminal kinase phosphorylation., Bo Liu, Jia-fa Wu, Yan-yan Zhan, Hang-zi Chen, Xiao-yan Zhang and Qiao Wu, 2007
- p53 mediates the negative regulation of MDM2 by orphan receptor TR3., Zhao BX, Chen HZ, Lei NZ, Li GD, Zhao WX, Zhan YY, Liu B, Lin SC, Wu Q, 2006
Awards
- 2018 - National High-level Young Talent
- 2016 - Invited Speaker at 'Future of Cancer Research' Symposium, UT MD Anderson Cancer Center
- 2012 - Outstanding International Student Award, University of Florida
- 2011 - Research Incentive Fund, University of Florida
- 2011 - Chinese Government Award for Outstanding Self-financed Students Abroad
