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Xiangying Li
Life Science
Peking University
Beijing
Language: English, Chinese
Stem Cells
Self-Renewal
Differentiation
Molecular Mechanisms
Cell Signaling
Environmental Factors
Cell Fate
Erythropoiesis
Gene Regulation
Tissue Regeneration
Areas of Focus
- Stem cell self-renewal and differentiation
- Molecular mechanisms of stem cell fate influenced by intracellular signaling pathways and external environmental factors
Work Experience
- 2017-present Researcher, Peking University College of Life Sciences
- 2017-present Researcher, Peking University-Tsinghua University Center for Life Sciences
- 2011-2017 Postdoctoral Fellow, Whitehead Institute for Biomedical Research, MIT
Academic Background & Achievements
- 2005-2011 PhD, University of Wisconsin-Madison
- 2003-2005 Master's, Boston University
- 1999-2003 Bachelor's, National Cheng Kung University
Publications
- Multidimensional profiling reveals GATA1-modulated stage-specific chromatin states and functional associations during human erythropoiesis, Li, D., Zhao, X.Y., Zhou, S., Hu, Q., Wu, F. and Lee H.Y., 2023
- Heterochromatin rewiring and domain disruption-mediated chromatin compaction during erythropoiesis, Li, D., Wu, F., Zhou, S., Huang, X.J. and Lee H.Y., 2023
- Thyroid hormone receptor beta and NCOA4 regulate terminal erythrocyte differentiation, Gao, X., Lee, H.Y., Li, W., Platt, R.J., Barrasa, M.I., Ma, Q., Elmes, R.R., Rosenfeld, M.G. and Lodish, H.F., 2017
- TGF-β inhibitors stimulate red cell production by enhancing self-renewal of BFU-E erythroid progenitors, Gao, X., Lee, H.Y., da Rocha, E.L., Zhang, C., Lu, Y.F., Li, D., Feng, Y., Ezike, J., Elmes, R.R., Barrasa, M.I., Cahan, P., Li, H., Daley, G.Q. and Lodish, H.F., 2016
- PPAR-α and glucocorticoid receptor synergize to promote erythroid progenitor self-renewal, Lee, H.Y., Gao, X., Barrasa, M.I., Li, H., Elmes, R.R., Peters, L.L. and Lodish, H.F., 2015
- Relocalizing genetic loci into specific subnuclear neighborhoods, Lee, H.Y., Johnson, K.D., Boyer, M. E. and Bresnick, E. H., 2011
- Building multifunctionality into a complex containing master regulators of hematopoiesis, Fujiwara, T., Lee, H.Y., Sanalkumar, R. and Bresnick, E. H., 2010
- Controlling hematopoiesis through sumoylation-dependent regulation of a GATA factor, Lee, H.Y., Johnson, K. D., Fujiwara, T., Boyer, M. E., Kim, S.-I. and Bresnick, E. H., 2009
Awards
- Charles H. Hood Foundation Postdoctoral Fellowship, 2015
- American Heart Association Graduate Student Scholarship, 2009
