Professor | Hao Guo | Asia Growth Partners

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Name	Hao Guo
Contact Information	guohao@xmu.edu.cn
Language ability	English, Chinese
Province	Fujian

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Name

Hao Guo

Contact Information

guohao@xmu.edu.cn

Language ability

English, Chinese

Province

Fujian

University/Lab Affiliation and Title	Xiamen University
Faculty	Life Sciences
Academic Background & Achievements	2009 - Bachelor's Degree in Biotechnology: Shandong University 2015 - Ph.D. in Cell Biology: Institute of Biophysics, Chinese Academy of Science 2021 - National High-Level Young Talent 2022 - Xiamen University Nanqiang Young Top Talent A-Class
Work Experience	2016-2021 - University of North Carolina at Chapel Hill - Postdoctoral Fellow 2021-2022 - University of North Carolina at Chapel Hill - Research Assistant Professor 2022 - Xiamen University, School of Life Sciences - Professor
Awards	2020: Joseph S. Pagano Award 2018-2019: Layton family grant for microbiome research 2017-2018: Layton family grant for microbiome research 2013-2014: “Triple-A” Outstanding Student, Chinese Academy of Science 2006-2007: National Base of Life Science and Technology Education Merit Scholarship, Shandong University 2005-2006: Shandong University Merit Scholarship

University/Lab Affiliation and Title

Xiamen University

Faculty

Life Sciences

Academic Background & Achievements

2009 - Bachelor's Degree in Biotechnology: Shandong University
2015 - Ph.D. in Cell Biology: Institute of Biophysics, Chinese Academy of Science
2021 - National High-Level Young Talent
2022 - Xiamen University Nanqiang Young Top Talent A-Class

Work Experience

2016-2021 - University of North Carolina at Chapel Hill - Postdoctoral Fellow
2021-2022 - University of North Carolina at Chapel Hill - Research Assistant Professor
2022 - Xiamen University, School of Life Sciences - Professor

Awards

2020: Joseph S. Pagano Award
2018-2019: Layton family grant for microbiome research
2017-2018: Layton family grant for microbiome research
2013-2014: “Triple-A” Outstanding Student, Chinese Academy of Science
2006-2007: National Base of Life Science and Technology Education Merit Scholarship, Shandong University
2005-2006: Shandong University Merit Scholarship

Areas of Focus	Gut microbiota and its role in diseases
Publications	Conversation between host and gut microbiota unveils a “silver bullet” therapeutic option for chemotherapy., Zhang MD, Guo H., 2024 Enterovirus 71 Activates Plasmacytoid Dendritic Cell-Dependent PSGL-1 Binding Independent of Productive Infection., Zhang X, Yin Z, Zhang J, Guo H, Li J, Nie X, Wang S, Zhang L., 2024 The TLR2/TLR6 ligand FSL-1 mitigates radiation-induced hematopoietic injury in mice and nonhuman primates., Brickey WJ, Caudell DL, Macintyre AN, Olson JD, Dai Y, Li S, Dugan GO, Bourland JD, O'Donnell LM, Tooze JA, Huang G, Yang S, Guo H, French MN, Schorzman AN, Zamboni WC, Sempowski GD, Li Z, Owzar K, Chao NJ, Cline JM, Ting JPY., 2023 Gut microbiota signatures and fecal metabolites in postmenopausal women with osteoporosis., Wang H, Liu J, Wu Z, Zhao Y, Cao M, Shi B, Chen B, Chen N, Guo H, Li N, Chen J, Xu R., 2023 Hypertension promotes microbial translocation and dysbiotic shifts in the fecal microbiome of nonhuman primates., Ravichandra Vemuri, Alistaire Ruggiero, Jordyn M Whitfield, Greg O Dugan, J Mark Cline, Masha R Block, Hao Guo, Kylie Kavanagh., 2022 Multi-omics analyses of radiation survivors identify radioprotective microbes and metabolites., Hao Guo, Wei-Chun Chou, Yunjia Lai, Kaixin Liang, Jason W Tam, W. June Brickey, Liang Chen, Nathan D. Montgomery, Xin Li, Lauren M. Bohannon, Anthony D. Sung, Nelson J. Chao, Jonathan U. Peled, Antonio L.C. Gomes, Marcel R.M. van den Brink, Matthew J. French, Andrew N. Macintyre, Gregory D. Sempowski, Xianming Tan, R. Balfour Sartor, Kun Lu and Jenny P.Y. Ting., 2020 AIM2 in regulatory T (Treg) cells restrains autoimmune diseases., Wei-Chun Chou, Zengli Guo, Hao Guo, Liang Chen, Ge Zhang, Ling Xie, Xianming Tan, Sara A. Gibson, Elena Rampanelli, Yan Wang, Stephanie A. Montgomery, W. June Brickey, Meng Deng, Leslie Freeman, Song Zhang, Maureen A Su, Xian Chen, Yisong Y. Wan, Jenny P.-Y. Ting., 2021 Gut Microbiota, NLR Proteins and Intestinal Homeostasis., Hao Guo, Sara A. Gibson, Jenny P.-Y. Ting., 2020 The Inhibitory Innate Immune Sensor NLRP12 Maintains a Threshold against Obesity by Regulating Gut Microbiota Homeostasis., Agnieszka D. Truax, Liang Chen, Jason W. Tam, Ning Cheng, Hao Guo, A. Alicia Koblansky, Wei-Chun Chou, Justin E. Wilson, W. June Brickey, Alex Petrucelli, Rongrong Liu, Daniel E. Cooper, Mark J. Koenigsknecht, Vincent B. Young, Mihai G. Netea, Rinke Stienstra, R. Balfour Sartor, Stephanie A. Montgomery, Rosalind A. Coleman, and Jenny P.-Y. Ting., 2018 The Toll–Like Receptor 2 agonist, FSL-1 lipopeptide, therapeutically mitigates acute radiation syndrome., Cathryn J. Kurkjian, Hao Guo, Nathan D. Montgomery, Ning Cheng, Hong Yuan, Joseph R. Merrill, Gregory D. Sempowski, W. June Brickey, and Jenny P.-Y. Ting., 2017 The binding of a monoclonal antibody to the apical region of SCARB2 blocks EV71 infection., Xuyuan Zhang, Pan Yang, Nan Wang, Jialong Zhang, Jingyun Li, Hao Guo, Xiangyun Yin, Zihe Rao, Xiangxi Wang, and Liguo Zhang., 2017 Human Blood CD1c+ Dendritic Cells Encompass CD5 high and CD5low Subsets That Differ Significantly in Phenotype, Gene Expression, and Functions., Xiangyun Yin, Haisheng Yu, Xiaoyang Jin, Jingyun Li, Hao Guo, Quanxing Shi, Zhao Yin, Yong Xu, Xuefei Wang, Rong Liu, Shouli Wang, and Liguo Zhang., 2017 SCARB2/LIMP-2 Regulates Interferon Production of Plasmacytoid Dendritic Cells by Mediating Endosomal Translocation of TLR9 and Nuclear Translocation of IRF7., Hao Guo, Jialong Zhang, Xuyuan Zhang, Yanbing Wang, Haisheng Yu, Xiangyun Yin, Jingyun Li, Peishuang Du, Joel Plumas, Laurence Chaperot, Jianzhu Chen, Lishan Su, Yongjun Liu, and Liguo Zhang., 2015

Areas of Focus

Gut microbiota and its role in diseases

Publications

Conversation between host and gut microbiota unveils a “silver bullet” therapeutic option for chemotherapy., Zhang MD, Guo H., 2024
Enterovirus 71 Activates Plasmacytoid Dendritic Cell-Dependent PSGL-1 Binding Independent of Productive Infection., Zhang X, Yin Z, Zhang J, Guo H, Li J, Nie X, Wang S, Zhang L., 2024
The TLR2/TLR6 ligand FSL-1 mitigates radiation-induced hematopoietic injury in mice and nonhuman primates., Brickey WJ, Caudell DL, Macintyre AN, Olson JD, Dai Y, Li S, Dugan GO, Bourland JD, O'Donnell LM, Tooze JA, Huang G, Yang S, Guo H, French MN, Schorzman AN, Zamboni WC, Sempowski GD, Li Z, Owzar K, Chao NJ, Cline JM, Ting JPY., 2023
Gut microbiota signatures and fecal metabolites in postmenopausal women with osteoporosis., Wang H, Liu J, Wu Z, Zhao Y, Cao M, Shi B, Chen B, Chen N, Guo H, Li N, Chen J, Xu R., 2023
Hypertension promotes microbial translocation and dysbiotic shifts in the fecal microbiome of nonhuman primates., Ravichandra Vemuri, Alistaire Ruggiero, Jordyn M Whitfield, Greg O Dugan, J Mark Cline, Masha R Block, Hao Guo, Kylie Kavanagh., 2022
Multi-omics analyses of radiation survivors identify radioprotective microbes and metabolites., Hao Guo, Wei-Chun Chou, Yunjia Lai, Kaixin Liang, Jason W Tam, W. June Brickey, Liang Chen, Nathan D. Montgomery, Xin Li, Lauren M. Bohannon, Anthony D. Sung, Nelson J. Chao, Jonathan U. Peled, Antonio L.C. Gomes, Marcel R.M. van den Brink, Matthew J. French, Andrew N. Macintyre, Gregory D. Sempowski, Xianming Tan, R. Balfour Sartor, Kun Lu and Jenny P.Y. Ting., 2020
AIM2 in regulatory T (Treg) cells restrains autoimmune diseases., Wei-Chun Chou, Zengli Guo, Hao Guo, Liang Chen, Ge Zhang, Ling Xie, Xianming Tan, Sara A. Gibson, Elena Rampanelli, Yan Wang, Stephanie A. Montgomery, W. June Brickey, Meng Deng, Leslie Freeman, Song Zhang, Maureen A Su, Xian Chen, Yisong Y. Wan, Jenny P.-Y. Ting., 2021
Gut Microbiota, NLR Proteins and Intestinal Homeostasis., Hao Guo, Sara A. Gibson, Jenny P.-Y. Ting., 2020
The Inhibitory Innate Immune Sensor NLRP12 Maintains a Threshold against Obesity by Regulating Gut Microbiota Homeostasis., Agnieszka D. Truax, Liang Chen, Jason W. Tam, Ning Cheng, Hao Guo, A. Alicia Koblansky, Wei-Chun Chou, Justin E. Wilson, W. June Brickey, Alex Petrucelli, Rongrong Liu, Daniel E. Cooper, Mark J. Koenigsknecht, Vincent B. Young, Mihai G. Netea, Rinke Stienstra, R. Balfour Sartor, Stephanie A. Montgomery, Rosalind A. Coleman, and Jenny P.-Y. Ting., 2018
The Toll–Like Receptor 2 agonist, FSL-1 lipopeptide, therapeutically mitigates acute radiation syndrome., Cathryn J. Kurkjian, Hao Guo, Nathan D. Montgomery, Ning Cheng, Hong Yuan, Joseph R. Merrill, Gregory D. Sempowski, W. June Brickey, and Jenny P.-Y. Ting., 2017
The binding of a monoclonal antibody to the apical region of SCARB2 blocks EV71 infection., Xuyuan Zhang, Pan Yang, Nan Wang, Jialong Zhang, Jingyun Li, Hao Guo, Xiangyun Yin, Zihe Rao, Xiangxi Wang, and Liguo Zhang., 2017
Human Blood CD1c+ Dendritic Cells Encompass CD5 high and CD5low Subsets That Differ Significantly in Phenotype, Gene Expression, and Functions., Xiangyun Yin, Haisheng Yu, Xiaoyang Jin, Jingyun Li, Hao Guo, Quanxing Shi, Zhao Yin, Yong Xu, Xuefei Wang, Rong Liu, Shouli Wang, and Liguo Zhang., 2017
SCARB2/LIMP-2 Regulates Interferon Production of Plasmacytoid Dendritic Cells by Mediating Endosomal Translocation of TLR9 and Nuclear Translocation of IRF7., Hao Guo, Jialong Zhang, Xuyuan Zhang, Yanbing Wang, Haisheng Yu, Xiangyun Yin, Jingyun Li, Peishuang Du, Joel Plumas, Laurence Chaperot, Jianzhu Chen, Lishan Su, Yongjun Liu, and Liguo Zhang., 2015

Microbiota Gut Microbial Community Bacteria Fungus Virus Immune System Diseases Diagnostic Methods Treatments

Jiang Weibin - Shanghai Normal University

Xiaoyan Pang - Shanghai Jiao Tong University

Xianen Zhang - University of Chinese Academy of Sciences

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