2009 - Ph.D. in Pharmacology: Oregon State University
2003 - Bachelor's in Bioengineering: Beijing Institute of Technology
Nearly 15 years of study and research in molecular biology and basic medicine in the USA
Published as first author in top international journals like Science, Immunity, and Current Biology
2018-present - Minjiang Scholar Distinguished Professor, Xiamen University
2014-2018 - Project Scientist, University of California, San Diego, Department of Dermatology, School of Medicine
2011-2014 - Postdoctoral Researcher, University of California, San Diego, Department of Dermatology, School of Medicine
2009-2011 - Postdoctoral Researcher, Oregon State University, College of Pharmacy
Research
Molecular Biology Basic Medicine Dermatology Skin Immunity Antimicrobial Peptides
Keratins in Skin Epidermal Development and Diseases, Ling-juan Zhang, 2018
Cathelicidin promotes inflammation by enabling binding of self-RNA to cell surface scavenger receptors, Toshiya Takahashi, Nikhil Nitin Kulkarni, Ernest Y Lee, Ling-juan Zhang, Gerard C.L. Wong, Richard L. Gallo, 2018
Interleukin-1 receptor knockout mice develop epidermal cysts and show an altered innate immune response following exposure to ultraviolet B radiation, Nikhil N Kulkarni, Christopher A Adase, Ling-juan Zhang, Andrew W Borkowski, Fengwu Li, James A Sanford, Daniel J Coleman, Carlos Aguilera, Arup K Indra, Richard L Gallo, 2017
Isolation and culture of primary mouse keratinocytes from neonatal and adult mouse skin, Fengwu Li, Chris Adase and Ling-juan Zhang, 2017
Activation of parathyroid hormone 2 receptor induces decorin expression and promotes wound repair, Emi Sato, Lingjuan Zhang, Robert Dorschner, Chris Adase, Biswa Choudhury, and Richard Gallo, 2017
A Co-drug of Butyric Acid Derived from Fermentation Metabolites of the Human Skin Microbiome Stimulates Adipogenic Differentiation of Adipose-Derived Stem Cells: Implications in Tissue Augmentation, Yanhan Wang, Ling-juan Zhang, Jinghua Yu, Stephen Huang, Zhenping Wang, Kimberly Ann Chun, Tammy Ling Lee, Richard L. Gallo and Chun-Ming Huang, 2017
Inhibition of HDAC8 and HDAC9 by microbial short-chain fatty acids breaks immune tolerance of the epidermis to TLR ligands, James A. Sanford, Ling-juan Zhang, Michael R. Williams, Jon A. Gangoiti, Chun-Ming Huang and Richard L. Gallo, 2016
Antimicrobial Peptide LL37 and MAVS Signaling Drive Interferon-β Production by Epidermal Keratinocytes during Skin Injury, Ling-juan Zhang, George L. Sen, Nicole L. Ward, Andrew Johnston, Kimberly Chun, Yifang Chen, Christopher Adase, James A. Sanford, Nina Gao, Melanie Chensee, Emi Sato, Yi Fritz, Jaymie Baliwag, Michael R. Williams, Tissa Hata, Richard L. Gallo, 2016
Non-coding double-stranded RNA and LL-37 induce growth factor expression from keratinocytes and endothelial cells, Christopher A. Adase, Andrew Borkowski, Ling-juan Zhang, Michael Williams, James A Sanford and Richard L. Gallo, 2016
The parathyroid hormone second receptor PTH2R, and its ligand tuberoinfundibular peptide of 39 residues TIP39, regulate intracellular calcium and influence keratinocyte differentiation, Emi Sato, Jun Muto, Ling-juan Zhang, Chris Adase, James A. Sanford, Toshi Takahashi, Teru Nakatsuji, Robert A. Lee, and Richard L Gallo, 2016
Antimicrobial peptides (Review article), Ling-juan Zhang and Richard Gallo, 2016
Molecular cartography of the human skin surface in 3D, Bouslimani A, Porto C, Rath CM, Berg-Lyon D, Ackermann G, Nakatsuji T, Zhang LJ, Borkowski AW, Meehan MJ, Dorrestein K, Gallo RL, Bandeira N, Knight R, Alexandrov T, Dorrestein PC, 2015
Dermal adipocytes protect against invasive Staphylococcus aureus skin infection, Ling-juan Zhang, Christian F. Guerrero-Juarez, Tissa Hata, Sagar P. Bapat, Raul Ramos, Maksim V. Plikus, Richard L. Gallo, 2015
Selective Ablation of Ctip2/Bcl11b in Epidermal Keratinocytes Triggers Atopic Dermatitis-like Skin Inflammatory Responses in Adult Mice, Ling-juan Zhang, Zhixing Wang, Gunjan Guha, Shan Li, Kateryna Kyrylkova, Chrissa Kioussi, Mark Leid, Gitali Ganguli-Indra, Arup K. Indra, 2012
Ctip2 is a dynamic regulator of epidermal proliferation and differentiation by integrating EGFR and Notch signaling, Zhang LJ, Bhattacharya S, Leid M, Ganguli-Indra G, Indra AK, 2012
Coordinated regulation of transcription factor Bcl11b activity in thymocytes by the mitogen-activated protein kinase (MAPK) pathways and protein sumoylation, Zhang LJ, Vogel WK, Liu X, Topark-Ngarm A, Arbogast BL, Maier CS, Filtz TM, Leid M, 2012
A Chicken Ovalbumin Upstream Promoter Transcription Factor I (COUP-TFI) Complex Represses Expression of the Gene Encoding Tumor Necrosis Factor α-induced Protein 8 (TNFAIP8), Zhang, L. J., Liu, X., Gafken, P. R., Kioussi, C., and Leid, M., 2009
Bcl11b represses a mature T-cell gene expression program in immature CD4(+)CD8(+) thymocytes, Kastner P, Chan S, Vogel WK, Zhang LJ, Topark-Ngarm A, Golonzhka O, Jost B, Le Gras S, Gross MK, Leid M, 2010
Keywords
Molecular BiologyBasic MedicineDermatologySkin ImmunityAntimicrobial PeptidesPreadipocytesKeratinocytesPsoriasisImmune RegulationTranslational Medicine
