Professor | Yingying Zhang | Asia Growth Partners

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Name	Yingying Zhang
Contact Information	y.zhang@xmu.edu.cn
Language ability	English, Chinese
Province	Fujian

Upload Avatar (500 x 500)

Name

Yingying Zhang

Contact Information

y.zhang@xmu.edu.cn

Language ability

English, Chinese

Province

Fujian

University/Lab Affiliation and Title	Xiamen University
Faculty	Life Sciences
Academic Background & Achievements	2006-2010 B.S.: School of Life Sciences, Xiamen University 2010-2016 Ph.D.: School of Life Sciences, Xiamen University
Work Experience	2017-present - Xiamen University - Assistant Professor 2020-2022 - University of California, Berkeley - Postdoc

University/Lab Affiliation and Title

Xiamen University

Faculty

Life Sciences

Academic Background & Achievements

2006-2010 B.S.: School of Life Sciences, Xiamen University
2010-2016 Ph.D.: School of Life Sciences, Xiamen University

Work Experience

2017-present - Xiamen University - Assistant Professor
2020-2022 - University of California, Berkeley - Postdoc

Areas of Focus	Intracellular signaling transduction Molecular mechanisms of programmed necrosis Immune responses to invasive viruses and tumor cells
Publications	RIP1 autophosphorylation is promoted by mitochondrial ROS and is essential for RIP3 recruitment into necrosome, Zhang Y#, Su SS#, Zhao S, Yang Z, Zhong CQ, Chen X, Cai Q, Yang ZH, Huang D, Wu R, Han J, 2017 Electrophysiologist shows a cation channel function of MLKL, Zhang Y, Han J, 2016 The RIP3-RIP1-NF-κB signaling axis is dispensable for necroptotic cells to elicit cross-priming of CD8+ T cells, Ren J#, Jia X, Zhao Y, Shi W, Lu J, Zhang Y, Wu J, Liang B, Wu R, Fu G, Han J, 2017 MLKL channel in necroptosis is octamer formed by tetramers in a dyadic process, Huang D#, Zheng X#, Wang ZA#, Chen X, He WT, Zhang Y, Xu JG, Zhao H, Shi W, Wang X, Zhu Y, Han J, 2017 Group-DIA: analyzing multiple data-independent acquisition mass spectrometry data files, Li, Y. #, Zhong, C.Q. #, Xu, X., Cai, S., Wu, X., Zhang, Y., Chen, J., Shi, J., Lin, S., and Han, J, 2015 Distinct roles of RIP1-RIP3 hetero- and RIP3-RIP3 homo-interaction in mediating necroptosis, Wu XN#, Yang ZH#, Wang XK, Zhang Y, Wan H, Song Y, Chen X, Shao J, Han J, 2014 Regulator of G-Protein Signaling 19 (RGS19) and Its Partner Gα-Inhibiting Activity Polypeptide 3 (GNAI3) Are Required for zVAD-Induced Autophagy and Cell Death in L929 Cells, Wu T, Li Y, Huang D, Han F, Zhang YY, Zhang DW, Han J, 2014 Mlkl knockout mice demonstrate the indispensable role of Mlkl in necroptosis, Wu J#, Huang Z#, Ren J#, Zhang Z, He P, Li Y, Ma J, Chen W, Zhang Y, Zhou X, Yang Z, Wu SQ, Chen L, Han J, 2013 Diverse Sequence Determinants Control Human and Mouse Receptor Interacting Protein 3 (RIP3) and Mixed Lineage Kinase domain-Like (MLKL) Interaction in Necroptotic Signaling, Chen W#, Zhou Z#, Li L#, Zhong CQ, Zheng X, Wu X, Zhang Y, Ma H, Huang D, Li W, Xia Z, Han J, 2013 Investigation of RIP3-dependent protein phosphorylation by quantitative phosphoproteomics, Wu X#, Tian L#, Li J, Zhang Y, Han V, Li Y, Xu X, Li H, Chen X, Chen J, Jin W, Xie Y, Han J, Zhong CQ*, 2012

Areas of Focus

Intracellular signaling transduction
Molecular mechanisms of programmed necrosis
Immune responses to invasive viruses and tumor cells

Publications

RIP1 autophosphorylation is promoted by mitochondrial ROS and is essential for RIP3 recruitment into necrosome, Zhang Y#, Su SS#, Zhao S, Yang Z, Zhong CQ, Chen X, Cai Q, Yang ZH, Huang D, Wu R, Han J*, 2017
Electrophysiologist shows a cation channel function of MLKL, Zhang Y, Han J*, 2016
The RIP3-RIP1-NF-κB signaling axis is dispensable for necroptotic cells to elicit cross-priming of CD8+ T cells, Ren J#, Jia X, Zhao Y, Shi W, Lu J, Zhang Y, Wu J, Liang B, Wu R, Fu G, Han J*, 2017
MLKL channel in necroptosis is octamer formed by tetramers in a dyadic process, Huang D#, Zheng X#, Wang ZA#, Chen X, He WT, Zhang Y, Xu JG, Zhao H, Shi W, Wang X, Zhu Y, Han J*, 2017
Group-DIA: analyzing multiple data-independent acquisition mass spectrometry data files, Li, Y. #, Zhong, C.Q. #, Xu, X., Cai, S., Wu, X., Zhang, Y., Chen, J., Shi, J., Lin, S., and Han, J*, 2015
Distinct roles of RIP1-RIP3 hetero- and RIP3-RIP3 homo-interaction in mediating necroptosis, Wu XN#, Yang ZH#, Wang XK, Zhang Y, Wan H, Song Y, Chen X, Shao J, Han J*, 2014
Regulator of G-Protein Signaling 19 (RGS19) and Its Partner Gα-Inhibiting Activity Polypeptide 3 (GNAI3) Are Required for zVAD-Induced Autophagy and Cell Death in L929 Cells, Wu T, Li Y, Huang D, Han F, Zhang YY, Zhang DW, Han J*, 2014
Mlkl knockout mice demonstrate the indispensable role of Mlkl in necroptosis, Wu J#, Huang Z#, Ren J#, Zhang Z, He P, Li Y, Ma J, Chen W, Zhang Y, Zhou X, Yang Z, Wu SQ, Chen L, Han J*, 2013
Diverse Sequence Determinants Control Human and Mouse Receptor Interacting Protein 3 (RIP3) and Mixed Lineage Kinase domain-Like (MLKL) Interaction in Necroptotic Signaling, Chen W#, Zhou Z#, Li L#, Zhong CQ, Zheng X, Wu X, Zhang Y, Ma H, Huang D, Li W, Xia Z, Han J*, 2013
Investigation of RIP3-dependent protein phosphorylation by quantitative phosphoproteomics, Wu X#, Tian L#, Li J, Zhang Y, Han V, Li Y, Xu X, Li H, Chen X, Chen J, Jin W, Xie Y, Han J*, Zhong CQ*, 2012

P38 Signaling Pathway Cell Cycle Regulation Cell Proliferation Cell Differentiation Senescence Immunity Development Tumorigenesis Rip3 Gsdmd

Yue Lou - Shanghai Normal University

Huiwen Yan - Central South University

Yefang Zhou - Central South University

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