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Bin Cao
Medical School
Xiamen University
Fujian
Language: Chinese, English
Placental Development
Molecular Mechanisms
Function Regulation
Pathogenic Microorganisms
Maternal-Fetal Interface
Preeclampsia
Fetal Growth Restriction
Pregnancy Diseases
Host Interaction
Disease Pathogenesis
Areas of Focus
- Molecular mechanisms of placental development and function regulation
- Interaction between pathogenic microorganisms and host at the maternal-fetal interface
- Pathogenesis of major pregnancy diseases such as preeclampsia and fetal growth restriction
Work Experience
- 2011-2018 - Washington University in St. Louis - Postdoctoral Researcher
- 2018-present - Xiamen University School of Medicine - Professor
Academic Background & Achievements
- 2000-2004 Bachelor of Science in Biological Sciences: Shanxi University
- 2005-2011 Doctor of Science in Developmental Biology: Institute of Zoology, Chinese Academy of Sciences
Publications
- Endogenous retrovirus-derived enhancers confer the transcriptional regulation of human trophoblast syncytialization., Miao Y, Hu X, Pan Z, Du C, Jiang J, Zheng W, Cai H, Wang Y, Deng W, Wang H, Lu J, Sun MA, Cao B, 2023
- Trophoblast PR-SET7 dysfunction induces viral mimicry response and necroptosis associated with recurrent miscarriage., Zhou X, Xu Y, Ren S, Yang N, Sun Y, Yang Q, Yue Zhang, Han Cai, Wenbo Deng, Jingsi Chen, Dunjin Chen, Bin Cao, Hongbo Qi, Haibin Wang, Jinhua Lu, 2023
- Regulation of endogenous retrovirus–derived regulatory elements by GATA2/3 and MSX2 in human trophoblast stem cells., Du C, Jiang J, Li Y, Yu M, Jin J, Chen Shuai, Fan H, Macfarlan T, Cao B, Sun MA, 2023
- Placental trophoblast syncytialization potentiates macropinocytosis via mTOR signaling to adapt to reduced amino acid supply., Shao X, Cao G, Chen D, Liu J, Yu B, Liu M, Li YX, Cao B, Sadovsky Y, Wang YL, 2021
- Zika virus infection during pregnancy in mice causes placental damage and fetal demise., Miner JJ, Cao B, Govero J, Smith AM, Fernandez E, Cabrera OH, Garber C, Noll M, Klein RS, Noguchi KK, Mysorekar IU, Diamond MS, 2016
- Inhibition of autophagy limits vertical transmission of Zika virus in pregnant mice., Cao B, Parnell LA, Diamond MS, Mysorekar IU, 2017
- ATG16L1 governs the placental syncytial barrier to infection and risk of premature birth in pregnant mice and women., Cao B, Macones C, Mysorekar IU, 2016
- Identification of desoxyrhapontigenin as a novel antiviral agent against congenital Zika virus infection., Yu W, Zhang B, Hong X, Cai H, Wang Y, Lu J, Hu X, Cao B, 2023
- Cellular and molecular atlas of the placenta from a COVID-19 pregnant woman infected at midgestation highlights the defective impacts on foetal health., Chen J, Du L, Wang F, Shao X, Wang X, Yu W, Bi S, Chen D, Pan X, Zeng S, Huang L, Liang Y, Li Y, Chen R, Xue F, Li X, Wang S, Zhuang M, Liu M, Lin L, Yan H, He F, Yu L, Jiang Q, Xiong Z, Zhang L, Cao B, Wang YL, Chen D, 2022
Awards
- 2018: National High-Level Young Talent
- 2018: Minjiang Scholar of Fujian Province
- 2018: High-Level Entrepreneurial and Innovative Talent of Fujian Province
- 2019: Xiamen City 'Double Hundred Plan' Talent
- 2020: Fujian Province Natural Science Foundation Outstanding Youth Project Recipient
- 2022: Chinese Zoological Society Youth Science and Technology Award
- 2017: STAT Wunderkinds Awards
- 2016: Laxmi Baxi Award, Society for Reproductive Investigation (SRI)
