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Run Fang
Medical School
Xiamen University
Fujian
Language: English, Chinese
Host Recognition
Pathogen Resistance
Innate Immunity
Autoimmune Diseases
Tumors
Cgas-Sting Pathway
Rlr-Mavs Pathway
Ikk Family Kinases
Genome-Wide Screening
Biochemical Techniques
Areas of Focus
- Mechanisms of host recognition and resistance to pathogen invasion
- Pathogen-host interactions
- Innate immunity and diseases (autoimmune diseases, tumors)
Work Experience
- 2023-present - Xiamen University School of Medicine - Professor
- 2018-2023 - Peking University School of Life Sciences - Postdoctoral Researcher
Academic Background & Achievements
- 2012-2018 PhD in Cell Biology: Peking University
- 2008-2012 Bachelor in Biotechnology: Huazhong University of Science and Technology
Publications
- ARMH3-mediated recruitment of PI4KB directs Golgi-to-endosome trafficking and activation of the antiviral effector STING, Fang, R#, Jiang, Q#, Jia, X, Jiang, Z, 2023
- Recent advances in the activation and regulation of the cGAS-STING pathway, Fang, R, Jiang, Q, Yu, X, Zhao, Z, Jiang, Z, 2022
- Golgi apparatus-synthesized sulfated glycosaminoglycans mediate polymerization and activation of the cGAMP sensor STING, Fang, R#, Jiang, Q#, Guan, Y, Gao, P, Zhang, R, Zhao, Z, Jiang, Z, 2021
- MAVS activates TBK1 and IKKε through TRAFs in NEMO dependent and independent manner, Fang R, Jiang Q, Zhou X, Wang C, Guan Y, Tao J, Xi J, Feng JM, Jiang Z, 2017
- NEMO-IKKβ Are Essential for IRF3 and NF-κB Activation in the cGAS-STING Pathway, Fang R, Wang C, Jiang Q, Lv M, Gao P, Yu X, Mu P, Zhang R, Bi S, Feng JM, Jiang Z, 2017
- The STING phase-separator suppresses innate immune signalling, Yu X, Zhang L, Shen J, Zhai Y, Jiang Q, Yi M, Deng X, Ruan Z, Fang R, Chen Z, Ning X, Jiang Z, 2021
- Inflammasome Activation Triggers Caspase-1-Mediated Cleavage of cGAS to Regulate Responses to DNA Virus Infection, Wang Y, Ning X, Gao P, Wu S, Sha M, Lv M, Zhou X, Gao J, Fang R, Meng G, Su X, Jiang Z, 2017
- The genetics of tiger pelage color variations, Xu X, Dong GX, Schmidt-Küntzel A, Zhang XL, Zhuang Y, Fang R, Sun X, Hu XS, Zhang TY, Yang HD, Zhang DL, Marker L, Jiang ZF, Li R, Luo SJ, 2017
- NLRP6 self-assembles into a linear molecular platform following LPS binding and ATP stimulation, Leng F, Yin H, Qin S, Zhang K, Guan Y, Fang R, Wang H, Li G, Jiang Z, Sun F, Wang DC, Xie C, 2020
Awards
- 2023-2029: Xiamen University Nanqiang Young Top Talent Support Program
