Professor | Run Fang | Asia Growth Partners

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Name	Run Fang
Contact Information	fangrun@xmu.edu.cn
Language ability	English, Chinese
Province	Fujian

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Name

Run Fang

Contact Information

fangrun@xmu.edu.cn

Language ability

English, Chinese

Province

Fujian

University/Lab Affiliation and Title	Xiamen University
Faculty	Medical
Academic Background & Achievements	2012-2018 PhD in Cell Biology: Peking University 2008-2012 Bachelor in Biotechnology: Huazhong University of Science and Technology
Work Experience	2023-present - Xiamen University School of Medicine - Professor 2018-2023 - Peking University School of Life Sciences - Postdoctoral Researcher
Awards	2023-2029: Xiamen University Nanqiang Young Top Talent Support Program

University/Lab Affiliation and Title

Xiamen University

Faculty

Medical

Academic Background & Achievements

2012-2018 PhD in Cell Biology: Peking University
2008-2012 Bachelor in Biotechnology: Huazhong University of Science and Technology

Work Experience

2023-present - Xiamen University School of Medicine - Professor
2018-2023 - Peking University School of Life Sciences - Postdoctoral Researcher

Awards

2023-2029: Xiamen University Nanqiang Young Top Talent Support Program

Areas of Focus	Mechanisms of host recognition and resistance to pathogen invasion Pathogen-host interactions Innate immunity and diseases (autoimmune diseases, tumors)
Publications	ARMH3-mediated recruitment of PI4KB directs Golgi-to-endosome trafficking and activation of the antiviral effector STING, Fang, R#, Jiang, Q#, Jia, X, Jiang, Z, 2023 Recent advances in the activation and regulation of the cGAS-STING pathway, Fang, R, Jiang, Q, Yu, X, Zhao, Z, Jiang, Z, 2022 Golgi apparatus-synthesized sulfated glycosaminoglycans mediate polymerization and activation of the cGAMP sensor STING, Fang, R#, Jiang, Q#, Guan, Y, Gao, P, Zhang, R, Zhao, Z, Jiang, Z, 2021 MAVS activates TBK1 and IKKε through TRAFs in NEMO dependent and independent manner, Fang R, Jiang Q, Zhou X, Wang C, Guan Y, Tao J, Xi J, Feng JM, Jiang Z, 2017 NEMO-IKKβ Are Essential for IRF3 and NF-κB Activation in the cGAS-STING Pathway, Fang R, Wang C, Jiang Q, Lv M, Gao P, Yu X, Mu P, Zhang R, Bi S, Feng JM, Jiang Z, 2017 The STING phase-separator suppresses innate immune signalling, Yu X, Zhang L, Shen J, Zhai Y, Jiang Q, Yi M, Deng X, Ruan Z, Fang R, Chen Z, Ning X, Jiang Z, 2021 Inflammasome Activation Triggers Caspase-1-Mediated Cleavage of cGAS to Regulate Responses to DNA Virus Infection, Wang Y, Ning X, Gao P, Wu S, Sha M, Lv M, Zhou X, Gao J, Fang R, Meng G, Su X, Jiang Z, 2017 The genetics of tiger pelage color variations, Xu X, Dong GX, Schmidt-Küntzel A, Zhang XL, Zhuang Y, Fang R, Sun X, Hu XS, Zhang TY, Yang HD, Zhang DL, Marker L, Jiang ZF, Li R, Luo SJ, 2017 NLRP6 self-assembles into a linear molecular platform following LPS binding and ATP stimulation, Leng F, Yin H, Qin S, Zhang K, Guan Y, Fang R, Wang H, Li G, Jiang Z, Sun F, Wang DC, Xie C, 2020

Areas of Focus

Mechanisms of host recognition and resistance to pathogen invasion
Pathogen-host interactions
Innate immunity and diseases (autoimmune diseases, tumors)

Publications

ARMH3-mediated recruitment of PI4KB directs Golgi-to-endosome trafficking and activation of the antiviral effector STING, Fang, R#, Jiang, Q#, Jia, X, Jiang, Z, 2023
Recent advances in the activation and regulation of the cGAS-STING pathway, Fang, R, Jiang, Q, Yu, X, Zhao, Z, Jiang, Z, 2022
Golgi apparatus-synthesized sulfated glycosaminoglycans mediate polymerization and activation of the cGAMP sensor STING, Fang, R#, Jiang, Q#, Guan, Y, Gao, P, Zhang, R, Zhao, Z, Jiang, Z, 2021
MAVS activates TBK1 and IKKε through TRAFs in NEMO dependent and independent manner, Fang R, Jiang Q, Zhou X, Wang C, Guan Y, Tao J, Xi J, Feng JM, Jiang Z, 2017
NEMO-IKKβ Are Essential for IRF3 and NF-κB Activation in the cGAS-STING Pathway, Fang R, Wang C, Jiang Q, Lv M, Gao P, Yu X, Mu P, Zhang R, Bi S, Feng JM, Jiang Z, 2017
The STING phase-separator suppresses innate immune signalling, Yu X, Zhang L, Shen J, Zhai Y, Jiang Q, Yi M, Deng X, Ruan Z, Fang R, Chen Z, Ning X, Jiang Z, 2021
Inflammasome Activation Triggers Caspase-1-Mediated Cleavage of cGAS to Regulate Responses to DNA Virus Infection, Wang Y, Ning X, Gao P, Wu S, Sha M, Lv M, Zhou X, Gao J, Fang R, Meng G, Su X, Jiang Z, 2017
The genetics of tiger pelage color variations, Xu X, Dong GX, Schmidt-Küntzel A, Zhang XL, Zhuang Y, Fang R, Sun X, Hu XS, Zhang TY, Yang HD, Zhang DL, Marker L, Jiang ZF, Li R, Luo SJ, 2017
NLRP6 self-assembles into a linear molecular platform following LPS binding and ATP stimulation, Leng F, Yin H, Qin S, Zhang K, Guan Y, Fang R, Wang H, Li G, Jiang Z, Sun F, Wang DC, Xie C, 2020

Host Recognition Pathogen Resistance Innate Immunity Autoimmune Diseases Tumors Cgas-Sting Pathway Rlr-Mavs Pathway Ikk Family Kinases Genome-Wide Screening Biochemical Techniques

Xia Meng - Zhejiang University

Yewei Ji - Zhejiang University

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